IMAMURA TAKUYA

イマムラタクヤ | IMAMURA TAKUYA

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://sites.google.com/view/imamuralabhiroshima/home

Research field (5)： Zoological sciences , Genetics , Laboratory animal science , Animals: biochemistry, physiology, behavioral science , Neuroscience - general

Research keywords (19)： ncRNA , lncRNA , pancRNA , 神経幹細胞 , ノンコーディングRNA , 進化 , 生物多様性 , 非コードRNA , エピジェネティクス , DNAメチル化 , 性分化 , 脳 , evolution , biodiversity , non-coding RNA , epigenetics , DNA methylation , sexual differentiation , brain

Research theme for competitive and other funds (17)：

2022 - 2025 ノンコーディングRNA獲得効果の定量化によるほ乳類大脳機能変遷の理解
2021 - 2023 福島第一原子力発電所周辺の潮間帯で見られた巻貝の生殖の季節性喪失の分子基盤
2019 - 2022 Experimental approach to understand the mechanism mediating epigenome formation in the primate brain by the evolutionary acquisition of non-coding RNAs
2019 - 2021 Regulation of retrotransposable elements in the mammalian neuron by Interleukin family members
2018 - 2021 Establishment of a novel CAR-T therapy for canine melanoma

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Papers (63)：

Dewi Yuliani, Fumihiro Morishita, Takuya Imamura, Tatsuya Ueki. Vanadium Accumulation and Reduction by Vanadium-Accumulating Bacteria Isolated from the Intestinal Contents of Ciona robusta. Marine Biotechnology. 2024. Epub ahead of print
飽田寛人、今村拓也. 種差と"個性". 生体の科学. 2024. 75. 40-44
Keitaro Yamanouchi, Shizuka Kato, Yukie Tanaka, Masanari Ikeda, Yukina Oshimo, Takanori Shiga, Kei Hatamoto, James Chambers, Takuya Imamura, Ryuji Hiramatsu, Kazuyuki Uchida, Fuko Matsuda, Takashi Matsuwaki, Tetsuya Kohsaka. Identification and characterization of dystrophin-locus-derived testis-specific protein: a testis-specific gene within the intronic region of the rat dystrophin gene. Journal of Reproduction and Development. 2024. Epub ahead of print
Boyang An, Akari Ando, Hiroto Akuta, Fumihiro Morishita, Takuya Imamura. Human-biased TMEM25 expression promotes expansion of neural progenitor cells to alter cortical structure in the developing brain. FEBS Letters. 2023. 597. 21. 2611-2625
Fumihiro Morishita, Toshihiro Horiguchi, Hiroto Akuta, Tatsuya Ueki, Takuya Imamura. Concomitant downregulation of neuropeptide genes in a marine snail with consecutive sexual maturation after a nuclear disaster in Japan. Frontiers in Endocrinology. 2023. 14. 1129666

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MISC (23)：

亀田朋典, 今村拓也, 滝沢琢己, 三浦史仁, 伊藤隆司, 中島欽一. ニューロンは神経活性化により新規DNAメチル化を介してエンハンサー活性を調節し,興奮性シナプス形成に影響する. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
今村拓也, 亀田朋典, 松田泰斗, 土井浩義, 古川佑介, 種村健太郎, 中島欽一. 子どもへの低用量化学物質暴露が誘発する情動認知行動影響とその評価系の開発幼若期ネオニコチノイド投与が成体マウス脳トランスクリプトームに及ぼす影響. The Journal of Toxicological Sciences. 2018. 43. Suppl. S26-S26
IMAMURA Takuya, KAMEDA Tomonori, MATSUDA Taito, DOI Hiroyoshi, FURUKAWA Yusuke, TANEMURA Kentaro, NAKASHIMA Kinichi. Detection of transcriptome-level alteration in the adult mouse brain following postnatal neonicotinoid administration. Annual Meeting of the Japanese Society of Toxicology. 2018. 45. 0. S2-4
亀田朋典, 今村拓也, 滝沢琢己, 三浦史仁, 伊藤隆司, 中島欽一. マウス海馬ニューロンは神経活動依存的にDNAメチロームを変動し,脱メチル化を介して遺伝子発現応答を高速化する. エピゲノムはどこまで操れるようになったか第11回日本エピジェネティクス研究会年会プログラム集理研シンポジウム平成29年. 2017
山本直樹, 山本直樹, 阿形清和, 中島欽一, 今村拓也. 長鎖ノンコーディングRNAはほ乳類ニューロンの完全増殖停止に必須である. Journal of Reproduction and Development. 2016. 62. Suppl Japanese Issue

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Patents (1)：

ゲノムDNAの標的メチル化領域の脱メチル化法

Books (1)：

Roles of epigenetics in the neural stem cell and neuron. In: Jacob Peedicayil, Dennis Grayson, Dimitri Avramopoulos (eds) Epigenetics in Psychiatry
Academic Press 2021 ISBN:9780128235775

Lectures and oral presentations (35)：

Evolutionary Acquisition of a Promoter-associated Non-coding RNA for MEIS1 Transcription Factor Contributes to Expansion of Human Neural Stem Cells
(57th Annual Meeting of the Japanese Society of Developmental Biologists 2024)
NRSN2 contributes to human neural stem cell proliferation through species-specific regulation of gene expression
(57th Annual Meeting of the Japanese Society of Developmental Biologists 2024)
Identification of species differences in structure and function of Commd3-Bmi1 loci in human/mouse neural stem cells
(The 17th Annual Meeting of the Japanese Society for Epigenetics 2024)
動物の種差をどのように理解し、そしてどう乗り越えていくのか
(第6回日本獣医薬理学・毒性学会春季研究会 2024)
Neural Stem Cell Dynamics Regulated by the Reduction of Reactive Oxygen Species through Human-specific Low-energy Metabolism
(Annual Meeting for Japanese Developmental Neuroscientists 2024)

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Education (3)：

1997 - 2001 東京大学大学院農学生命科学研究科獣医学専攻
1993 - 1997 The University of Tokyo
1991 - 1993 The University of Tokyo College of Arts and Sciences

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (10)：

2020/04 - 現在 Hiroshima University Graduate School of Integrated Sciences for Life Professor
2015/07 - 2020/03 Kyushu University
2013/04 - 2015/06 Kyushu University
2012/04 - 2013/03 Kyoto University
2008/03 - 2012/03 Kyoto University

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Committee career (4)：

2023/09 - 現在日本繁殖生物学会評議委員
2022/04 - 現在日本生殖内分泌学会理事
2018/04 - 現在 BMC Genomics Associate Editor
2016/04 - 現在日本繁殖生物学会編集委員

Association Membership(s) (7)：

THE JAPANESE SOCIETY OF VETERINARY SCIENCE , JAPANESE SOCIETY OF ANIMAL SCIENCE , 日本エピジェネティクス研究会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 日本発生生物学会 , 日本繁殖生物学会 , THE JAPAN NEUROSCIENCE SOCIETY

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