Rchr

J-GLOBAL ID：200901031928205534 Update date: Sep. 30, 2022

Nishie Wataru

ニシエワタル | Nishie Wataru

Affiliation and department：
Job title： Research Assistant
Homepage URL (1)： http://www.derm-hokudai.jp/

Research field (1)： Dermatology

Research keywords (4)： Pattern formation in skin , Biological function of basement membrane proteins , 水疱性皮膚疾患 , Blistering skin disease

Research theme for competitive and other funds (7)：

2016 - 2019 免疫寛容が破綻し発症する画期的水疱性類天疱瘡モデルの作成と応用
2016 - 2018 17型コラーゲン発現制御による画期的水疱症モデルの作成と応用
2016 - 2017 クラススイッチ導入モノクローナル抗体を用いた水疱性類天疱瘡の病態機序の解明
2015 - 2016 経口免疫寛容を応用した水疱性類天疱瘡自己抗体の産生抑制
2012 - 2016 17型コラーゲン発現制御による画期的水疱症モデルの作成と応用

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Papers (40)：

Ken Natsuga, Mika Watanabe, Wataru Nishie, Hiroshi Shimizu. Life before and beyond blistering: The role of collagen XVII in epidermal physiology. Experimental dermatology. 2019. 28. 10. 1135-1141
Mayumi Kamaguchi, Hiroaki Iwata, Wataru Nishie, Ellen Toyonaga, Hideyuki Ujiie, Ken Natsuga, Yoshimasa Kitagawa, Hiroshi Shimizu. The direct binding of collagen XVII and collagen IV is disrupted by pemphigoid autoantibodies. Laboratory investigation; a journal of technical methods and pathology. 2019. 99. 1. 48-57
Ken Muramatsu, Hideyuki Ujiie, Ichiro Kobayashi, Wataru Nishie, Kentaro Izumi, Takamasa Ito, Norihiro Yoshimoto, Ken Natsuga, Hiroaki Iwata, Hiroshi Shimizu. Regulatory T-cell dysfunction induces autoantibodies to bullous pemphigoid antigens in mice and human subjects. The Journal of allergy and clinical immunology. 2018. 142. 6. 1818-1830
Tuusa J, Lindgren O, Tertsunen HM, Nishie W, Kokkonen N, Huilaja L, Izumi K, Herukka SK, Miettunen J, Shimizu H, et al. BP180 Autoantibodies Target Different Epitopes in Multiple Sclerosis or Alzheimer's Disease than in Bullous Pemphigoid. The Journal of investigative dermatology. 2018. 139. 2. 293-299
Mai Y, Nishie W, Izumi K, Yoshimoto N, Morita Y, Watanabe M, Toyonaga E, Ujiie H, Iwata H, Fujita Y, et al. Detection of anti-BP180 NC16A autoantibodies after the onset of dipeptidyl peptidase-IV inhibitor-associated bullous pemphigoid: a report of three patients. The British journal of dermatology. 2018. 179. 3. 790-791

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Education (2)：

- 1995 Hirosaki University School of Medicine
- 1995 Hirosaki University Faculty of Medicine

Professional career (1)：

博士(医学) (北海道大学)

Awards (1)：

2007 - 北海道大学大学院医学研究科平成19年度北海道大学医学部医学研究科優秀論文賞

Association Membership(s) (5)：

THE HOKKAIDO MEDICAL SOCIETY , 日本臨床皮膚科医会 , THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY , 日本皮膚科学会 , Japanese Dermatological Association

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