Rchr
J-GLOBAL ID:200901034013234450
Update date: Oct. 16, 2024
Sawa Hirofumi
サワ ヒロフミ | Sawa Hirofumi
Affiliation and department:
Job title:
Professor
Other affiliations (1):
-
University of Zambia
School of Veterinary Medicine
Visiting Professor
Homepage URL (1):
http://www.czc.hokudai.ac.jp/pathobiol/
Research field (4):
Molecular biology
, Experimental pathology
, Cell biology
, Virology
Research keywords (10):
Vaccinology
, 感染症疫学
, モデルマウス
, 細胞内輸送
, ウイルス学
, animal model
, trafficking
, Cellular Biology
, Molecular Pathology
, Virology
Research theme for competitive and other funds (24):
- 2022 - 2025 The role of MHC class I transactivator NLRC5 in COVID-19
- 2021 - 2024 VIrome analysis of bats in Indonesia
- 2016 - 2023 「ネオウイルス学」の国際活動支援
- 2021 - 2022 ネオウイルス学:生命の源流から超個体、そしてエコ・スフィアーへ
- 2016 - 2021 Comprehensive investigation and functional analysis of endogenous viruses and endogenous viral elements in hematophagous arthropods and their host animals
- 2016 - 2021 Neo-virology: the raison d'etre of viruses
- 2016 - 2020 Investigation of latent pathogenic viruses in Latin America and South-eastern Asia by virome analysis
- 2008 - 2011 Functional analysis of equine herpesvirus-1 receptor and its application for infection prevention
- 2007 - 2008 ウイルスを鋳型とした金属微粒子3次元規則配列構造の構築
- 2007 - 2008 Investigations for new pathogeneses of sudden deafness and Bell's palsy
- 2006 - 2007 Analysis of West Nile virus neuroinvasion using in vitro blood-brain barrier models
- 2004 - 2006 Investigation on the pathogenesis of herpetic facial nerve paralysis
- 2004 - 2006 Analysis of human synovial sarcoma oncoprotein SYT-SSX and its therapeutic application.
- 2003 - 2004 DNA damage checkpoint mechanism and its relation to aging
- 2002 - 2003 Molecular investigation on prognostic factors and development of an tailor-made therapy for Hunt syndrome.
- 1999 - 2003 女性性殖器官に特異的な新規マトリックスメタロプロテアーゼMIFRの機能解析
- 2001 - 2002 Analysis of transforming mechanism of human synovial sarcoma oncogene SYT-SSX
- 2000 - 2001 Investigation on the pathogenesis of acute peripheral facial palsy caused by herpes simplex virus reactivation.
- 2000 - 2001 The preventive effects of angiotensin II receptor blocker on lethal ventricular arrhythmias, a leading cause of sudden cardiac death, in experimental failing animal hearts
- 1999 - 2000 Investigation on CDDP resistance of Head and Neck Cancer.
- 1998 - 2000 Analysis of mechanisms of demyelination in progressive multifocal leukoencephalopathy
- 1997 - 1999 血管内皮成長因子(VEGF)を併用した虚血心筋再潅流の研究
- 1997 - 1999 Analysis of apoptotic mechanism of cerebellar granular cells
- 1996 - 1997 Yeast One Hybrid法によるJC virus複製機構の検討
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Papers (523):
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Hisano Yajima, Yuki Anraku, Yu Kaku, Kanako Terakado Kimura, Arnon Plianchaisuk, Kaho Okumura, Yoshiko Nakada-Nakura, Yusuke Atarashi, Takuya Hemmi, Daisuke Kuroda, et al. Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nature Communications. 2024. 15. 1
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Kittiya Intaruck, Koshiro Tabata, Yukari Itakura, Nijiho Kawaguchi, Mai Kishimoto, Agus Setiyono, Ekowati Handharyani, Hayato Harima, Takashi Kimura, William W Hall, et al. Characterization of a mammalian orthoreovirus isolated from the large flying fox, Pteropus vampyrus, in Indonesia. The Journal of general virology. 2024. 105. 9
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Kei Konishi, Shinji Kusakabe, Nijiho Kawaguchi, Takao Shishido, Naoto Ito, Michiko Harada, Satoshi Inoue, Ken Maeda, William W Hall, Yasuko Orba, et al. β-d-N4-hydroxycytidine, a metabolite of molnupiravir, exhibits in vitro antiviral activity against rabies virus. Antiviral research. 2024. 229. 105977-105977
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Koshiro Tabata, Shintaro Kobayashi, Yukari Itakura, Gabriel Gonzalez, Chilekwa F. Kabamba, Shinji Saito, Michihito Sasaki, William W. Hall, Hirofumi Sawa, Yasuko Orba. Increased production of orthoflavivirus single-round infectious particles produced in mammalian cells at a suboptimal culture temperature of 28°C. Journal of Virological Methods. 2024. 329. 115007-115007
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Nijiho Kawaguchi, Yukari Itakura, Kittiya Intaruck, Takuma Ariizumi, Michiko Harada, Satoshi Inoue, Ken Maeda, Naoto Ito, William W Hall, Hirofumi Sawa, et al. Reverse genetic approaches allowing the characterization of the rabies virus street strain belonging to the SEA4 subclade. Scientific reports. 2024. 14. 1. 18509-18509
more...
MISC (225):
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伊東詩織, 喜多俊介, 上村健太朗, 上村健太朗, 上村健太朗, 上村健太朗, 岩間湧希, 田所高志, 澤洋文, 澤洋文, et al. Structural basis for antiviral activity of a nucleoside analogue targeting dengue virus RNA-dependent RNA polymerase. 日本薬学会年会要旨集(Web). 2024. 144th
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田畑耕史郎, 田畑耕史郎, 田畑耕史郎, 安楽佑樹, 多賀祐喜, 佐々木道仁, 佐々木道仁, 板倉友香里, 板倉友香里, 後藤希代子, et al. IgA抗体の自己重合反応による四量体形成とその応用. 日本抗体学会学術大会プログラム・抄録集(Web). 2023. 2nd
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日下部伸治, 日下部伸治, 鳥羽晋輔, 鳥羽晋輔, 井澤政明, 丸山優樹, 丸山優樹, 上村健太朗, 上村健太朗, 上村健太朗, et al. Generation of severe COVID-19 mouse model by treatment with Cyclophosphamide. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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播磨勇人, 邱永晋, 山岸潤也, 梶原将大, CHANGULA Katendi, 佐々木道仁, MWEENE Aaron S, 澤洋文, 石原加奈子, HANG’OMBE Bernard M, et al. Genetic characterization of various herpesviruses in bats in Zambia. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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板倉友香里, 板倉友香里, 田畑耕史郎, 田畑耕史郎, 大場靖子, 大場靖子, 大場靖子, 澤洋文, 澤洋文, 澤洋文, et al. Establishment of antiviral neutralizing antibody targeting intracellular process of viral replication. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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Patents (2):
-
JCウイルスのVP-1に対するsiRNA、およびそれを含有してなる医薬組成物
-
JCウイルスagnoを対象としたPMLの治療
Books (6):
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プリオン病と遅発性ウイルス感染症
金原出版 2010
-
Molecular Biology of Tumor Virus Gene Products.
Research Signpost 2009
-
DNA viruses, Methods and Protocols.
Humana Press 2005
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Understanding of Minamata disease. Methylmercury poisoning in Minamata and Niigata, Japan
Japan Public Health Association 2001
-
Endokrine und zellbiologische aspekte der arteriosklerose 10
Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung 1996
more...
Professional career (1):
Work history (3):
- 2023/04 - 現在 Hokkaido University Institute for Vaccine Research and Development: HU-IVReD Professor
- 2021/04 - 2023/03 international institute for Zoonosis Control, Hokkaido University Division of Molecular pathobiology professor
- 2005/04 - 2021/03 Research center for Zoonosis Control, Hokkaido University Division of Molecular Pathobiology Profesor
Awards (2):
- 2024/02 - Hokkaido University Hokkaido University Presidential Commendation for Education and Research Excellence Award
- 2016/02 - Hokkaido University Hokkaido University Presidential Commendation for Education and Research Excellence Award
Association Membership(s) (9):
Global Virus network
, 分子生物学会
, 日本病理学会
, 日本内科学会
, 日本生化学会
, 日本神経病理学会
, 日本循環器学会
, 日本ウイルス学会
, American Society of MicrobiologyAmerican Society for Biochemistry and Molecular BiologyInternational Society for Neurovirology
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