Rchr
J-GLOBAL ID:200901034013234450   Update date: Oct. 16, 2024

Sawa Hirofumi

サワ ヒロフミ | Sawa Hirofumi
Affiliation and department:
Job title: Professor
Other affiliations (1):
  • University of Zambia  School of Veterinary Medicine   Visiting Professor
Homepage URL  (1): http://www.czc.hokudai.ac.jp/pathobiol/
Research field  (4): Molecular biology ,  Experimental pathology ,  Cell biology ,  Virology
Research keywords  (10): Vaccinology ,  感染症疫学 ,  モデルマウス ,  細胞内輸送 ,  ウイルス学 ,  animal model ,  trafficking ,  Cellular Biology ,  Molecular Pathology ,  Virology
Research theme for competitive and other funds  (24):
  • 2022 - 2025 The role of MHC class I transactivator NLRC5 in COVID-19
  • 2021 - 2024 VIrome analysis of bats in Indonesia
  • 2016 - 2023 「ネオウイルス学」の国際活動支援
  • 2021 - 2022 ネオウイルス学:生命の源流から超個体、そしてエコ・スフィアーへ
  • 2016 - 2021 Comprehensive investigation and functional analysis of endogenous viruses and endogenous viral elements in hematophagous arthropods and their host animals
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Papers (523):
  • Hisano Yajima, Yuki Anraku, Yu Kaku, Kanako Terakado Kimura, Arnon Plianchaisuk, Kaho Okumura, Yoshiko Nakada-Nakura, Yusuke Atarashi, Takuya Hemmi, Daisuke Kuroda, et al. Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nature Communications. 2024. 15. 1
  • Kittiya Intaruck, Koshiro Tabata, Yukari Itakura, Nijiho Kawaguchi, Mai Kishimoto, Agus Setiyono, Ekowati Handharyani, Hayato Harima, Takashi Kimura, William W Hall, et al. Characterization of a mammalian orthoreovirus isolated from the large flying fox, Pteropus vampyrus, in Indonesia. The Journal of general virology. 2024. 105. 9
  • Kei Konishi, Shinji Kusakabe, Nijiho Kawaguchi, Takao Shishido, Naoto Ito, Michiko Harada, Satoshi Inoue, Ken Maeda, William W Hall, Yasuko Orba, et al. β-d-N4-hydroxycytidine, a metabolite of molnupiravir, exhibits in vitro antiviral activity against rabies virus. Antiviral research. 2024. 229. 105977-105977
  • Koshiro Tabata, Shintaro Kobayashi, Yukari Itakura, Gabriel Gonzalez, Chilekwa F. Kabamba, Shinji Saito, Michihito Sasaki, William W. Hall, Hirofumi Sawa, Yasuko Orba. Increased production of orthoflavivirus single-round infectious particles produced in mammalian cells at a suboptimal culture temperature of 28°C. Journal of Virological Methods. 2024. 329. 115007-115007
  • Nijiho Kawaguchi, Yukari Itakura, Kittiya Intaruck, Takuma Ariizumi, Michiko Harada, Satoshi Inoue, Ken Maeda, Naoto Ito, William W Hall, Hirofumi Sawa, et al. Reverse genetic approaches allowing the characterization of the rabies virus street strain belonging to the SEA4 subclade. Scientific reports. 2024. 14. 1. 18509-18509
more...
MISC (225):
  • 伊東詩織, 喜多俊介, 上村健太朗, 上村健太朗, 上村健太朗, 上村健太朗, 岩間湧希, 田所高志, 澤洋文, 澤洋文, et al. Structural basis for antiviral activity of a nucleoside analogue targeting dengue virus RNA-dependent RNA polymerase. 日本薬学会年会要旨集(Web). 2024. 144th
  • 田畑耕史郎, 田畑耕史郎, 田畑耕史郎, 安楽佑樹, 多賀祐喜, 佐々木道仁, 佐々木道仁, 板倉友香里, 板倉友香里, 後藤希代子, et al. IgA抗体の自己重合反応による四量体形成とその応用. 日本抗体学会学術大会プログラム・抄録集(Web). 2023. 2nd
  • 日下部伸治, 日下部伸治, 鳥羽晋輔, 鳥羽晋輔, 井澤政明, 丸山優樹, 丸山優樹, 上村健太朗, 上村健太朗, 上村健太朗, et al. Generation of severe COVID-19 mouse model by treatment with Cyclophosphamide. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
  • 播磨勇人, 邱永晋, 山岸潤也, 梶原将大, CHANGULA Katendi, 佐々木道仁, MWEENE Aaron S, 澤洋文, 石原加奈子, HANG’OMBE Bernard M, et al. Genetic characterization of various herpesviruses in bats in Zambia. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
  • 板倉友香里, 板倉友香里, 田畑耕史郎, 田畑耕史郎, 大場靖子, 大場靖子, 大場靖子, 澤洋文, 澤洋文, 澤洋文, et al. Establishment of antiviral neutralizing antibody targeting intracellular process of viral replication. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
more...
Patents (2):
  • JCウイルスのVP-1に対するsiRNA、およびそれを含有してなる医薬組成物
  • JCウイルスagnoを対象としたPMLの治療
Books (6):
  • プリオン病と遅発性ウイルス感染症
    金原出版 2010
  • Molecular Biology of Tumor Virus Gene Products.
    Research Signpost 2009
  • DNA viruses, Methods and Protocols.
    Humana Press 2005
  • Understanding of Minamata disease. Methylmercury poisoning in Minamata and Niigata, Japan
    Japan Public Health Association 2001
  • Endokrine und zellbiologische aspekte der arteriosklerose 10
    Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung 1996
more...
Professional career (1):
  • 医学博士 (北海道大学大学院医学研究科)
Work history (3):
  • 2023/04 - 現在 Hokkaido University Institute for Vaccine Research and Development: HU-IVReD Professor
  • 2021/04 - 2023/03 international institute for Zoonosis Control, Hokkaido University Division of Molecular pathobiology professor
  • 2005/04 - 2021/03 Research center for Zoonosis Control, Hokkaido University Division of Molecular Pathobiology Profesor
Awards (2):
  • 2024/02 - Hokkaido University Hokkaido University Presidential Commendation for Education and Research Excellence Award
  • 2016/02 - Hokkaido University Hokkaido University Presidential Commendation for Education and Research Excellence Award
Association Membership(s) (9):
Global Virus network ,  分子生物学会 ,  日本病理学会 ,  日本内科学会 ,  日本生化学会 ,  日本神経病理学会 ,  日本循環器学会 ,  日本ウイルス学会 ,  American Society of MicrobiologyAmerican Society for Biochemistry and Molecular BiologyInternational Society for Neurovirology
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