Tanaka Yoshihiko

Affiliation and department：
Other affiliations (2)：

Fukuoka Dental College Oral Medicine Research Center
Fukuoka Dental College Animal Center Director

Homepage URL (1)： https://rd.fdcnet.ac.jp/search/detail.html?systemId=2512129703d13a74f96f7227eaa32594&lang=ja

Research keywords (5)：口腔感染症 , 歯周病 , カンジダ症 , 自閉症 , 免疫応答

Research theme for competitive and other funds (11)：

2023 - 2026 Immunological study of the gut-mouth organ interaction as a link between human periodontal disease and the intestine microbiome
2023 - 2026 Investigation of periodontal immune regulation based on microbiome and development of new treatment methods
2020 - 2023 Basic research for new immunological therapies based on a pathological mechanism of periodontal disease
2019 - 2021 口腔感染症において病原微生物がネオ・セルフとしてはたす役割の解明
2018 - 2020 歯周病原細菌がもたらす脳神経系と免疫系のクロストーク

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Papers (33)：

主な研究業績. 2024
Masashi Shin, Aya Matsushima, Jun-Ichi Nagao, Yoshihiko Tanaka, Hidemitsu Harada, Koji Okabe, John D Bartlett. Mobility gene expression differences among wild-type, Mmp20 null and Mmp20 over-expresser mice plus visualization of 3D mouse ameloblast directional movement. Scientific Reports. 2023. 13. 1. 18829-18829
Ryuichiro Miyazawa, Jun-Ichi Nagao, Ken-Ichi Arita-Morioka, Minoru Matsumoto, Junko Morimoto, Masaki Yoshida, Takeshi Oya, Koichi Tsuneyama, Hideyuki Yoshida, Yoshihiko Tanaka, et al. Dispensable Role of Aire in CD11c+ Conventional Dendritic Cells for Antigen Presentation and Shaping the Transcriptome. ImmunoHorizons. 2023. 7. 1. 140-158
Jun-ichi Nagao, Sari Kishikawa, Honami Tanaka, Kenji Toyonaga, Yuka Narita, Kanae Negoro-Yasumatsu, Sonoko Tasaki, Ken-ichi Arita-Morioka, Jiro Nakayama, Yoshihiko Tanaka. Pathobiont-responsive Th17 cells in gut-mouth axis provoke inflammatory oral disease and are modulated by intestinal microbiome. Cell Reports. 2022. 40. 10. 111314-111314
Yasumatsu, K, Nagao, J, Arita-Morioka, K, Narita, Y, Tasaki, S, Toyoda, K, Kido, H, Tanaka, Y. Bacterial-induced maternal interleukin-17A pathway promotes autistic-like behaviors in mouse offspring. Exp. Anim. 2020. 69. 250-260

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MISC (3)：

田中芳彦. 腸内細菌叢と免疫細胞による歯周病の増悪化. 歯界展望. 2024. 144. 4. 684-689
田中芳彦. 腸でおこる歯周病の発症と重症化の仕組み-腸内細菌叢をターゲットとした歯周病の予防と治療への応用-. 全国大学歯科衛生士教育協議会雑誌. 2024. 13. 7-12
田中芳彦. Pathobiont-responsive Th17 cells in gut-mouth axis provoke periodontitis-Role of oral bacteria and intestinal microbiome-. 月刊臨床免疫・アレルギー科. 2023. 79. 5

Books (4)：

口腔微生物学-感染と免疫- 第8版
学建書院 2024 ISBN:9784762476549
口腔微生物学・免疫学第5版
医歯薬出版 2021 ISBN:9784263458662
Janeway's Immunobiology
2019
The immune system 4th edition
2016

Lectures and oral presentations (10)：

歯周病と腸内細菌の関係〜腸の免疫応答が歯周病の重症化をおこす仕組み〜
(【特別講演】一般社団法人佐賀県歯科医師会令和6年度佐賀県医科・歯科連携による糖尿病等対策事業 2024)
腸内環境がおこす歯周病の免疫応答の仕組み
(【特別講演】日本病巣疾患研究会 2024)
腸でおこる歯周病の免疫応答の仕組み
(【特別講演】令和5年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会 2023)
腸内細菌叢による歯周病の重症化の仕組み
(【シンポジウム】第66回日本脳循環代謝学会学術集会 2023)
腸内細菌叢と免疫細胞による歯周病の増悪化
(【シンポジウム】第316回東京歯科大学学会、東京歯科大学研究プロジェクト(ウェルビーイングプロジェクト)共催 2023)

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Education (3)：

MBA Kyushu University
Ph.D. Kumamoto University
M.D. Kumamoto University

Professional career (1)：

M.D., Ph.D., MBA

Work history (7)：

2019/10 - 現在 Fukuoka Dental College
2019/04 - 現在 Fukuoka Dental College Animal Center
2013/09 - 現在 Fukuoka Dental College
2008/01 - 2013/08 Kyushu University Medical Institute of Bioregulation
2004/09 - 2007/12 Kyushu University Medical Institute of Bioregulation

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Awards (1)：

2004 - 米国免疫学会米国免疫学会研究奨励賞

Association Membership(s) (6)：

JAPANESE SOCIETY FOR BACTERIOLOGY , THE JAPANESE SOCIETY FOR MEDICAL MYCOLOGY , The American Association of Immunologists , JAPANESE SOCIETY OF PERIODONTOLOGY , THE JAPANESE SOCIETY FOR IMMUNOLOGY , JAPANESE ASSOCIATION FOR ORAL BIOLOGY

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