Research theme for competitive and other funds (6):
2022 - 2025 Identification of the two-component sensor mutations which suppress fimbriation of a periodontopathogenic bacteria
2019 - 2022 Search for the molecules related to fungal-bacterial interactions in denture plaque microbiota
2011 - 2013 Development of an efficient transformation and gene expression system for a fastidi-ous oral anaerobe
2007 - 2008 Development and application of the microarray for the isolation of target genes of transcriptional regulators in periodontal pathogens
2003 - 2005 Elucidation of Mechanisms in Fimbrial Morphogenesis in Periodontopathogens
Study on two-component signal transduction systems in oral anaerobes
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Papers (28):
Ayaka Kawamura, Kiyoshi Nishikawa, Haruka Iida, Ken Miyazawa, Shigemi Goto, Yoshiaki Hasegawa. The AtoC family response regulator upregulates an operon encoding putative outer membrane proteins sorted by type IX secretion system in Porphyromonas gingivalis. Journal of Oral Biosciences. 2023. 65. 1. 80-87
Wakako Fujinami, Kiyoshi Nishikawa, Shogo Ozawa, Yoshiaki Hasegawa, Jun Takebe. Correlation between the relative abundance of oral bacteria and Candida albicans in denture and dental plaques. Journal of Oral Biosciences. 2021. 63. 2. 175-183
Kiyoshi Nishikawa, Yoshiaki Hasegawa. 16S rRNA metagenomics of denture plaque microbiota and denture care. The Journal of the Japan Dental Association. 2019. 72. 5. 383-392
Hasegawa Yoshiaki, Nishikawa Kiyoshi, Masuda Takashi, Noguchi Toshihide, Yoshimura Fuminobu. Analysis of a new two-component regulatory system in Porphyromonas gingivalis. Journal of the Japanese Association of Periodontology. 2002. 44. 104-104
Mutational analysis of the periplasmic sensor domain of the Porphyromonas gingivalis FimS histidine kinase.
(ASM Microbe 2016 (Boston) 2016)
Functional mapping of the sensor domain of a Porphyromonas gingivalis histidine kinase: construction and application of an expression vector for the major periodontal pathogen.
(BMB2015 Biochemistry and Molecular Biology 2015)
Natural competence of Tannerella forsythia: application to the insertional mutation of a two-component system-related gene
(35th Annual meeting of MBSJ 2012)