AKIRA MIYAJIMA

ミヤジマアキラ | AKIRA MIYAJIMA

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://uro.med.u-tokai.ac.jp/

Research field (1)： Urology

Research theme for competitive and other funds (27)：

2021 - 2026 Establishment of focal therapy for localized prostate cancer with cancer localization and tracking technology based on the artificial intelligence
2022 - 2025 Development of a novel kidney cancer drug targeting mitochondrial molecules
2018 - 2021 The effect of the low ND1 expression in renal cancer cells on the intracellular ROS, tumor metastasis and proliferation
2015 - 2018 Elucidation of refractory mechanism to the molecular targeted therapy for renal cell carcinoma
2015 - 2018 尿路上皮癌の進展におけるケモカインの発現制御と機能解析

2015 - 2017 Antitumor effect by regulation of EZH2 on urothelial carcinoma

2014 - 2017 Novel anti-cancer therapeutic strategy with mTORC1/2 inhibitor against bladder cancer

2014 - 2016 Elucidation of development mechanism in renal cell carcinoma: focus on fatty acid receptor and visceral fat.

2013 - 2015 NVP-BEZ235 Therapy for Bladder Cancer and Prevention of Tumor Invasion and Metastasis

2013 - 2015 New treatment strategy of refractory prostate cancer by regulation of androgen-androgen receptor axis and PI3K/Akt pathway

2012 - 2015 Elucidation of molecular targets based on epithelial-mesenchymal transition for the treatment of renal cell carcinoma

2010 - 2013 ホルモン不応性前立腺癌における、微小環境に着目したマイクロRNAの機能解析

2011 - 2013 Establishment of the novel treatment strategy against urothelial carcinoma controlling for the transcription factors

2011 - 2012 Liposomal IL-21/IL-15 Gene Therapy in an Orthotopic Bladder Cancer Model and Prevention of Tumor Invasion and Metastasis

2011 - 2012 Liposomal PTEN Gene Therapy in an Orthotopic Bladder Cancer Modeland Prevention of Tumor Invasion and Metastasis

2009 - 2011 Microenviroment and organ specific metastases in urological cancers as tools to elucidate molecular mechanism of carcinogenesis and tumor development.

2008 - 2010 The chemotherapeutic strategy with a novel NF-kappa B inhibitor in bladder cancer

2007 - 2009 前立腺癌の血管新生におけるアンギオテンシンIIの機能解析

2007 - 2008 Mechanism of renal cell carcinoma carcinogenesis arising in the acquired cystic kidney disease

2006 - 2007 Establishment of new treatment strategy for diabetic erectile dysfunction

2006 - 2007 Development of new chemotherapy for refractory prostate cancer

2004 - 2006 難治性前立腺癌におけるアンギオテンシンII受容体阻害剤の抗腫瘍効果に関する研究

2004 - 2006 Pathophysiological role of NF k B and the efficacy of a novel NF K B inhibitor in urological cancers

2004 - 2005 Anew strategy utilizing a novel NF-κB inhibitor for renal allograft rejection.

2004 - 2005 Gene therapy for hormone-refractory prostate cancer targeting androgen receptor

1996 - 1996 膀胱癌のCDDPによるアポトーシス誘導とその耐性機序に関する研究

1993 - 1993 泌尿器科悪性腫瘍に対する化学療法における活性酸素の役割

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Papers (258)：

Takato Uchida, Masanori Hasegawa, Tatsuya Umemoto, Nobuyuki Nakajima, Masahiro Nitta, Yoshiaki Kawamura, Sunao Shoji, Akira Miyajima. Predictors of surgical difficulty according to surgical proficiency in robot-assisted radical prostatectomy. Surgical endoscopy. 2024
Yoshiaki Kawamura, Takato Uchida, Tatsuo Kano, Tatsuya Umemoto, Nobuyuki Nakajima, Masahiro Nitta, Masanori Hasegawa, Sunao Shoji, Akira Miyajima. Transcatheter renal arterial embolization for intractable urinary fistula occurring after robot-assisted partial nephrectomy: a case report. CEN case reports. 2024
Yoshiaki Kawamura, Takato Uchida, Tatsuya Umemoto, Nobuyuki Nakajima, Masahiro Nitta, Masanori Hasegawa, Sunao Shoji, Akira Miyajima. Robot-assisted radical prostatectomy in a patient with prostate cancer complicated by benign prostate hypertrophy with middle lobe hypertrophy. Journal of surgical case reports. 2024. 2024. 2. rjae077
Masahiro Nitta, Moeko Tazawa, Kumpei Takahashi, Jun Naruse, Kazuya Oda, Tatsuo Kano, Takato Uchida, Tatsuya Umemoto, Takahiro Ogawa, Yoshiaki Kawamura, et al. Variations in predictors for urinary continence recovery at different time periods following robot-assisted radical prostatectomy. Asian journal of endoscopic surgery. 2024. 17. 1. e13243
Masahiro Nitta, Moeko Tazawa, Jun Naruse, Kazuma Takeda, Kazuya Oda, Takato Uchida, Tatsuo Kano, Tatsuya Umemoto, Nobuyuki Nakajima, Masanori Hasegawa, et al. Two Cases of Intractable Radiation-Induced Hemorrhagic Cystitis Treated with Transcatheter Embolization. The Tokai journal of experimental and clinical medicine. 2023. 48. 4. 114-116

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MISC (43)：

Sunao Shoji, Mayura Nakano, Kohei Uemura, Kumpei Takahashi, Tatsuo Kano, Soichiro Yuzuriha, Izumi Hanada, Takahiro Ogawa, Tatsuya Umemoto, Masayoshi Kawakami, et al. USEFULNESS OF PROSTATE SPECIFIC ANTIGEN-GLYCOSYLATION ISOMER FOR SIGNIFICANT CANCER DETECTION AND PATHOLOGICAL FINDINGS OF INDEX PROSTATE CANCERS ON MAGNETIC RESONANCE IMAGING-TRANSRECTAL ULTRASOUND FUSION IMAGE-GUIDED BIOPSY: A PROSPECTIVE MULTICENTER STUDY. JOURNAL OF UROLOGY. 2022. 207. 5. E685-E686
小路直, 高橋薫平, 花田いずみ, 鹿野竜生, 杠総一郎, 梅本達哉, 黒田悟史, 小川貴博, 川上正能, 新田正広, et al. 前立腺癌に対する高密度焦点式超音波療法をもちいたFocal Therapy:180例の臨床成績. 泌尿器画像診断・治療技術研究会プログラム・抄録. 2021. 8th
小路直, 花田いずみ, 小川貴博, 中野まゆら, 座光寺秀典, 朝長哲朗, 平岩真一郎, 長谷部光泉, 田尻琢磨, 宮嶋哲. MRI-TRUS融合画像ガイド下生検により診断された限局性前立腺癌に対する高密度焦点式超音波療法をもちいたFocal Therapy. 泌尿器外科. 2019. 32. 臨増. 754-754
小路直, 平岩真一郎, 花田いずみ, 小川貴博, 中野まゆら, 橋田和靖, 長谷部光泉, 田尻琢磨, 宮嶋哲. MRI-TRUS融合画像ガイド下前立腺生検における病理組織学的所見の臨床的予測因子. 日本泌尿器科学会総会(Web). 2019. 107th. OP-452
小路直, 平岩真一郎, 田尻琢磨, 長谷部光泉, 宮嶋哲. 前立腺significant cancer検出における3D shear wave elastographyの有用性. 超音波医学. 2019. 46. Supplement (CD-ROM). S424-S424

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Lectures and oral presentations (234)：

前立腺癌細胞に対する5FU系経口抗癌剤S-1とドセタキセル併用による抗腫瘍効果およびその作用機序の検討
(第19回泌尿器科分子・細胞研究会 2010)
腎周囲脂肪組織原発混合型脂肪肉腫の一例
(第601回日本泌尿器科学会東京地方会 2010)
膀胱全摘術後9年目に残存尿道および鼡径部リンパ節へ再発した膀胱癌の1例
(第600回日本泌尿器科学会東京地方会 2009)
局所進行性前立腺癌に対する外部照射治療の成績
(第25回前立腺シンポジウム 2009)
Gemcitabineとcisplatinの化学療法に起因したreversible posterior leukoencephalopathy syndromeの一例
(第74回日本泌尿器科学会東部総会 2009)

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Education (1)：

- 1990 Keio University Faculty of Medicine

Professional career (1)：

Degree of Medical Science (Keio University)

Work history (6)：

2017/04 - 現在 Tokai University School of Medicine, Department of Urology
2015/02 - 2017/03 慶應義塾大学医学部泌尿器科准教授
2006/04 - 2015/01/31 慶應義塾大学医学部専任講師
2003/07/01 - 2006/04/01 慶應義塾大学医学部泌尿器科助手
1996/07 - 2003/06/30 防衛医科大学校泌尿器科学講座助手

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Committee career (7)：

2021/04 - 現在日本泌尿器科学会理事
2020/06 - 現在日本腎臓学会理事
2013/10 - 2018/03 日本内分泌外科学会専門医制度資格認定委員
2013/10 - 日本泌尿器内視鏡学会腹腔鏡技術認定審査委員
2009/04 - 2012 日本泌尿器科学会 Audio-Visual Journal of JUA モニター委員委員

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Awards (2)：

2013/11 - 日本泌尿器内視鏡学会総会総会賞単孔式腹腔鏡下副腎摘除術におけるcross-over techniqueの有用性に関する検討
2008/04 - 日本泌尿器科学会総会賞若い泌尿器科医を対象とした体腔鏡下手術手技向上の試み

Association Membership(s) (6)：

Japan association of endocrine surgeon , 日本泌尿器内視鏡学会 , 日本泌尿器科学会 , 日本腎臓学会 , 日本癌治療学会 , 日本内視鏡外科学会

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