Rchr
J-GLOBAL ID：200901037335989430   Update date: Jan. 30, 2024

Ohmori Yoshihiro

オオモリ ヨシヒロ | Ohmori Yoshihiro
Affiliation and department：
Meikai University School of Dentistry, Faculty of Dentistry, Division of Microbiology and Immunology, Department of Oral Biology and Tissue Engineering

About Meikai University School of Dentistry, Faculty of Dentistry, Division of Microbiology and Immunology, Department of Oral Biology and Tissue Engineering


Job title： Professor
Research field  (2)： Oral medicine (pathology) ,  Oral medicine
Research keywords  (22)： transcription factor ,  oral cancer ,  口腔微生物学 ,  分子生物学 ,  ケモカイン ,  サイトカイン ,  情報伝達 ,  転写調節 ,  遺伝子発現制御 ,  炎症 ,  感染 ,  免疫 ,  Transcriptional Regulation ,  Signal Transduction ,  Molecular Biology ,  Chemokine ,  Cytokine ,  Oral Microbiology・Immunology ,  Gene Expression ,  Inflammation ,  Infection ,  Immunology
Research theme for competitive and other funds  (25)：
  • 2020 - 2023 Inactivation of IFN-induced chemokines by DPP4 and its clinical significance in oral cancer
  • 2019 - 2022 口腔癌のインターフェロン耐性機構の解明と免疫エピゲノム併用療法の有効性の検討
  • 2018 - 2021 脂肪酸合成を標的とした口腔癌の増殖・進展メカニズムの解析
  • 2016 - 2019 マウス舌癌モデルにおける癌免疫編集機構によるインターフェロン耐性獲得機構
  • 2000 - 2018 炎症性遺伝子の発現調節機構の解析
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Papers (83)：
  • Ari Matsumoto, Miki Hiroi, Kazumasa Mori, Nobuharu Yamamoto, Yoshihiro Ohmori. Differential Anti-Tumor Effects of IFN-Inducible Chemokines CXCL9, CXCL10, and CXCL11 on a Mouse Squamous Cell Carcinoma Cell Line. Medical sciences (Basel, Switzerland). 2023. 11. 2
  • Ryosuke Ushio, Miki Hiroi, Ari Matsumoto, Kazumasa Mori, Nobuharu Yamamoto, Yoshihiro Ohmori. Enhanced Cytotoxic Effects in Human Oral Squamous Cell Carcinoma Cells Treated with Combined Methyltransferase Inhibitors and Histone Deacetylase Inhibitors. Biomedicines. 2022. 10. 4
  • Hana Yamaguchi, Miki Hiroi, Kazumasa Mori, Ryosuke Ushio, Ari Matsumoto, Nobuharu Yamamoto, Jun Shimada, Yoshihiro Ohmori. Simultaneous Expression of Th1- and Treg-Associated Chemokine Genes and CD4+, CD8+, and Foxp3+ Cells in the Premalignant Lesions of 4NQO-Induced Mouse Tongue Tumorigenesis. Cancers. 2021. 13. 8
  • Hana Yamaguchi, Miki Hiroi, Yoshihiro Ohmori. Silencing of the interferon-inducible gene Ifi204/p204 induces resistance to interferon-γ-mediated cell growth arrest of tumor cells. Cytokine. 2019. 118. 80-92
  • Iguchi M, Hiroi M, Kanegae H, Ohmori Y. Costimulation of Murine Osteoblasts with Interferon-γ and Tumor Necrosis Factor-α Induces Apoptosis through Downregulation of Bcl-2 and Release of Cytochrome c from Mitochondria. Mediators of inflammation. 2018. 2018. 3979606
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MISC (104)：
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Books (7)：
  • 口腔微生物学・免疫学 第4版
    医歯薬出版 2016 ISBN:9784263457917
  • 口腔微生物学・免疫学 第3版
    医歯薬出版 2010 ISBN:9784263456361
  • Intracellular Signaling Pathways Mediating Inflammatory Gene Expression in Mononuclear Phagocytes : in Signal Transduction in Leukocytes : Role of G-Protein Related and Other Pathways
    CRC Press 1995
  • Regulation of diversity in macrophage activation IN Mononuclear Phagocytes in Cell Biology (G. Lopez-Berestein and J. Klostergaard, ed.)
    CRC Press 1993
  • Transmembrane and intracellular signaling events in LPS-stimulated macrophages IN Macrophage Pathogen Interactions (B. Zwilling and T. Eisenstein, eds.)
    Marcel Dekker 1993
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Education (2)：
  • - 1987 Meikai University
  • - 1983 Josai Dental University School of Dentistry
Professional career (1)：
  • Ph.D (Meikai University)
Work history (7)：
  • 2022/04 - 現在 Meikai University School of Dentistry
  • 2000 - 2022/03 Meikai University School of Dentistry Professor
  • 1992 - 2000 Cleveland Clinic Lerner Research Institute Immunology Project Staff
  • 1990/10 - 1992 Cleveland Clinic Lerner Research Institute, Research Associate
  • 1990/04 - 1990/09 Meikai University School of Dentistry
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Committee career (2)：
  • 2009 - 2012 歯科基礎医学会 理事
  • Japanese Association for Oral Biologye Councilor
Association Membership(s) (10)：
日本口腔外科学会 ,  歯科基礎医学会 ,  Society for Leukocyte Biology ,  American Society for Biochemistry and Molecular Biology ,  International Cytokine and Interferon Society ,  Japanese Association for Oral Biologye ,  American Society for Biochemistry and Molecular Biology (ASBMB) ,  Society for Leukocyte Biology ,  International Cytokine Society ,  International Society for Interferon and Cytokine Reaseach (ISICR)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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