Michiaki Yamakage

• 2023 - 2026 低親和性神経成長因子受容体選択的リガンド:LM11A-31による術後認知機能障害予防戦略
• 2022 - 2025 人工呼吸器関連肺障害における肺血管内皮グリコカリックスの動態と新たな治療法の探索
• 2019 - 2022 Prevention strategies for perioperative neuroinflammation related diseases with a focus on stabilization of intestinal microbiota
• 2016 - 2019 Analysis of a relationship between postoperative delirium or/and cognitive dysfunction and aging by transcriptome analysis
• 2015 - 2019 Living with chronic non-cancer pain receiving opioid therapy
2013 - 2016 Analysis of cytoskeleton related genes in elderly patients
2012 - 2016 Investigation about the sex differences and postoperative nausea and vomiting using epigenome-wide association study.
2012 - 2016 Determination of the molecular mechanism of volatile anesthetics using transcriptome analysis in thymo-cortico neurons of mice.
2011 - 2013 Association of epigenetic modulation in the TACR1 gene with opioid-induced nausea and vomiting
2011 - 2012 Association of genetic polymorphisms of the GABRB3 gene with the concentration of propofol at loss of consciousness
2009 - 2011 Effect of the new inhalation anesthetic Desflurane on airway hyperreactivity
2006 - 2008 Mechanisms and actions of anesthetics on hyperreactive airway in chronic cigarette-smoking model
2003 - 2005 Mechanism of Dilatory Action of Volatile Anesthetics on Hyperreactive Airway in Chronic Obstructive Pulmonary Disease Model
2000 - 2002 Investigation of Mechanisms of Volatile Anesthetic Action by the Use of Gene Expression Techniques
1998 - 1999 気道平滑筋に及ぼす環境変化と麻酔薬との相互作用ならびに作用機序の解明
周術期の体温管理
血液凝固系
麻酔薬の作用機序の解明

• Makishi Maeda, Yusuke Yoshikawa, Sho Ohno, Tomohiro Chaki, Michiaki Yamakage. Differences in circulating blood volume changes during emergence from general anesthesia in transcatheter aortic valve implantation and MitraClip implantation. Journal of anesthesia. 2024. 38. 4. 489-495
• Wataru Sakai, Tomohiro Chaki, Shunsuke Tachibana, Yuki Ichisaka, Yuko Nawa, Tomohiro Nawa, Michiaki Yamakage. INJEX50 could improve the success rate of local anesthesia for arterial cannulation in the pediatric intensive care unit: A randomized, double-blind, single-center study. Paediatric anaesthesia. 2024
• Yusuke Yoshikawa, Makishi Maeda, Tatsuya Kunigo, Tomoe Sato, Kanako Takahashi, Sho Ohno, Tomoki Hirahata, Michiaki Yamakage. Effect of using hypotension prediction index versus conventional goal-directed haemodynamic management to reduce intraoperative hypotension in non-cardiac surgery: A randomised controlled trial. Journal of clinical anesthesia. 2024. 93. 111348-111348
• Yusuke Yoshikawa, Shunsuke Oura, Masatoshi Kanda, Tomohiro Chaki, Naoyuki Hirata, Mitsutaka Edanaga, Michiaki Yamakage. Comparison of the negative effect of remimazolam and propofol on cardiac contractility: Analysis of a randomised parallel-group trial and a preclinical ex vivo study. Clinical and experimental pharmacology & physiology. 2024. 51. 3. e13840
• Tomoe Sato, Yasuaki Sawashita, Yusuke Yoshikawa, Michiaki Yamakage. Japanese Traditional Herbal Medicine, Rikkunshito, Partially Suppresses Inflammatory Responses in Myocardial Ischemia/Reperfusion Injury. Cureus. 2024. 16. 2. e54485

ｍore...

• Hironobu Ueshima, Atsushi Sawada, Michiaki Yamakage, Mineko Fujimiya. Blocking of the saphenous and obturator nerves using a pectineus muscle plane block. Journal of Clinical Anesthesia. 2020. 60. 2-3
• 澤下泰明, 平田直之, 吉川裕介, 寺田拡文, 山蔭道明. 遠隔虚血プレコンディショニングは非アシル化グレリンの分泌によってJAK2/STAT3経路が活性化し心臓虚血再灌流傷害を減弱させる. 日本麻酔科学会学術集会(Web). 2020. 67th
• 横山竜也, 新山幸俊, 吉川裕介, 高田幸昌, 山蔭道明. Anesthetic Management with Percutaneous Cardiopulmonary Support for Emergency Tracheotomy in a Patient with a Thyroid Tumor who Had Severe Tracheal Stenosis from Thyroid Tumor. 麻酔. 2018. 67. 11
• 佐藤優真, 君塚基修, 吉川裕介, 枝長充隆, 山蔭道明. 妊娠高血圧症を合併した多発性硬化症の妊婦に硬膜外麻酔のみで帝王切開を施行した1症例. 日本臨床麻酔学会誌. 2018. 38. 6
• 畠山陽介, 枝長充隆, 吉川裕介, 松本友美, 寺田拡文, 木井菜摘, 山蔭道明. Sonoclotで無輸血手術が可能となった血小板増加症を合併した大動脈弁輪拡張症の1症例. Cardiovascular Anesthesia. 2018. 22. Suppl

ｍore...

• - 1993 Sapporo Medical University Postgraduate School of Medicine
• - 1988 Sapporo Medical University School of Medicine

• Ph.D. (Medical)

• 2003 - 北海道麻酔科学会 第16回高橋賞
• 2003 - Takahashi Prize of Hokkaido Society of Anesthesiologiists
• 2002 - 日本麻酔科学会 第21回山村記念賞
• 2002 - Yamamura Memorial Prize, Japan Society of Anesthesiologists
• 2000 - 上原記念財団奨励研究
2000 - The Uehara Memorial Foundation, Incentive Grant
1994 - 日本学術振興会海外特別研究員
1994 - Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellowship for Research Abroad

New Opioid研究会 ,  日本ACLS協会 ,  日本医師会 ,  日本静脈麻酔・Infusion technology研究会 ,  日本臨床体温研究会 ,  日本歯科麻酔学会 ,  日本循環制御医学会 ,  日本手術医学会 ,  日本心臓血管麻酔学会 ,  日本集中治療医学会 ,  日本医学教育学会 ,  日本蘇生学会 蘇生法指導医 ,  日本ペインクリニック学会 認定医 ,  日本臨床麻酔学会 ,  International Anesthesia and Research Society ,  American Society of Anesthesiologists ,  麻酔科指導医 ,  日本麻酔科学会 麻酔科専門医 ,  Association of New Opioid ,  Japan Medical Association ,  Japnese Society of Intravenous Anesthesia and Infusion Technology ,  Japanese Association of Clinical Thermomedicine ,  Japanese Society of Dental Anesthesia ,  Japanese Association for Circulatory Control ,  Japanese Association for Operative Medicine ,  Japanese Society of Cardiovascular Anesthesia ,  The Japanese Society of Intensive Care Medicine ,  Japanese Society of Medical Education ,  Japanese Society of Resuscitation ,  Japanese Society of Pain Clinic ,  Japanese Society of Clinical Anesthesia ,  International Anesthesia and Research Society ,  American Society of Anesthesiologists ,  Japanese Society of Anesthesiologists