Seki Toshinobu

セキトシノブ | Seki Toshinobu

Affiliation and department：
Job title： Professor

Research field (3)： Education - general , Clinical pharmacy , Pharmaceuticals - analytical and physicochemistry

Research keywords (3)：薬学教育 , ドラッグデリバリーシステム , Drug Delivery

Research theme for competitive and other funds (8)：

2018 - 2021 A gastrointestinal absorption simulation system that incorporates dynamic changes in the dissolution state of drugs
2014 - 2017 Controlled disposition of tacrolimus in skin with atopic dermatitis using stimulus-responsible rotaxane nanoparticles
2011 - 2013 Studies on disposition of tacrolimus after topical application using several experimental models including a new hybrid skin-model
2008 - 2010 Study on the relationship between dermal structure and disposition of tacrolimus in skin after the topical application
2004 - 2005 Drug delivery systems by pulmonary administration for treatment of respiratory infections.

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Papers (96)：

Hinako Kikuchi, Yuki Nakamura, Chika Inoue, Sayaka Nojiri, Miho Koita, Minori Kojima, Hiroki Koyama, Ryotaro Miki, Toshinobu Seki, Yuya Egawa. Hydrogen Peroxide-Triggered Conversion of Boronic Acid-Appended Insulin into Insulin and Its Application as a Glucose-Responsive Insulin Formulation. Molecular pharmaceutics. 2021. 18. 11. 4224-4230
Ryotaro Miki, Tomoya Yamauchi, Kosuke Kawashima, Yuya Egawa, Toshinobu Seki. Multinuclear NMR Study on the Formation and Polyol-Induced Deformation Mechanisms of Wormlike Micelles Composed of Cetyltrimethylammonium Bromide and 3-Fluorophenylboronic Acid. Langmuir : the ACS journal of surfaces and colloids. 2021. 37. 11. 3438-3445
Yuki Kobayashi, Yu Kojima, Ryotaro Miki, Toshinobu Seki, Yuya Egawa. Rotaxa-polymeric-gelation of acrylamides with vinyl-beta-cyclodextrin. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY. 2020
Yuki Kobayashi, Yu Kojima, Ryotaro Miki, Toshinobu Seki, Yuya Egawa. Rotaxa-polymeric-gelation of acrylamides with vinyl-β-cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2020
Yui Ohno, Tomohiro Seki, Yu Kojima, Ryotaro Miki, Yuya Egawa, Osamu Hosoya, Keizo Kasono, Toshinobu Seki. Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations. JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES. 2019. 5. 1

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MISC (57)：

山内知也, 三木涼太郎, 江川祐哉, 関俊暢. Multi-nuclear NMR analysis for collapse mechanism of worm-like micelle gel by adding glucose in cetyltrimethylammonium bromide/3-fluorophenylboronic acid system. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
山崎聖仁, 三木涼太郎, 江川祐哉, 関俊暢. Sugar responsive rheological studies in diboronic acid derivative/polyvinyl alcohol mix system. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
菊地陽花子, 中村優季, 三木涼太郎, 関俊暢, 江川祐哉. An insulin analog activatable by hydrogen peroxide and its possibility for sugar-responsive insulin formulations. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
Yuya Egawa, Tomohiro Seki, Ryotaro Miki, Toshinobu Seki. Sugar-responsive smart materials based on phenylboronic acid and cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2019. 94. 1-2
Yuya Egawa, Tomohiro Seki, Ryotaro Miki, Toshinobu Seki. Sugar-responsive smart materials based on phenylboronic acid and cyclodextrin. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY. 2019. 94. 1-2. 1-10

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Education (2)：

Professional career (1)：

Work history (1)：

Association Membership(s) (6)：

日本シクロデキストリン学会 , 国際コントロールリリース学会 , 日本DDS学会 , 日本高分子学会 , 日本薬剤学会 , 日本薬学会

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