Research theme for competitive and other funds (9):
2023 - 2026 How does daily exercise contribute to maintaining the elasticity of the heart?
2021 - 2024 糖尿病が骨格筋の易疲労性を引き起こす血管内皮依存性メカニズムの解明
2020 - 2023 Multi-layered elucidation of the effects of exercise therapy for early metabolic syndrome
2019 - 2023 Influence of non-vascular cells in accelerated coronary aging in diabetes
2016 - 2019 Role of pulmonary sympathetic nerves in the regulation of the pulmonary circulation by beta-receptors on pulmonary macrophages during chronic intermittent hypoxia
2016 - 2018 Synchrotron radiation investigation of cardiac contractile protein dynamics at end diastole in a type 2 prediabetes model rat
2015 - 2018 Investigation of the mechanism of the exercise pressor reflex using a selective chemical denervation method.
2014 - 2016 Role of microvascular dysfunction in the cardiovascular center for development of hypertension
2008 - 2010 Neural regulatory mechanisms of cardiopulmonary function in hypoxic conditions.
Show all
Papers (73):
Shuhei Murase, Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Ayumu Konno, Hirokazu Hirai, Taku Saito, Sakae Tanaka, Keisuke Shinohara, et al. Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans. Nature Biomedical Engineering. 2023
Yasuhiro Sawada, Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Keisuke Shinohara, Takuya Kishi, Ayumu Konno, Hirokazu Hirai, Makoto Ayaori, et al. Brain- Targeted Mechanical Intervention Using Passive Head Motion Can Have an Antihypertensive Effect. CIRCULATION. 2022. 146
Takashi Sonobe, Hirotsugu Tsuchimochi, Hisashi Maeda, James T Pearson. Increased contribution of KCa channels to muscle contraction induced vascular and blood flow responses in sedentary and exercise trained ZFDM rats. The Journal of physiology. 2022
Eng Leng Saw, James T. Pearson, Daryl O. Schwenke, Pujika Emani Munasinghe, Hirotsugu Tsuchimochi, Shruti Rawal, Sean Coffey, Philip Davis, Richard Bunton, Isabelle Van Hout, et al. Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications. Cardiovascular Diabetology. 2021. 20. 1
James Pearson, Huiling Jin, Mark Waddingham, Takashi Sonobe, Hisashi Maeda, Jennifer Ngo, Connie Ow, Vijayakumar Sukumaran, Takeshi Ogo, Mikiyasu Shirai, et al. EFFECTS OF A GLUCAGON LIKE PEPTIDE-1 AGONIST AND RHO-KINASE INHIBITOR ON PULMONARY AND RIGHT VENTRICLE FUNCTION IN PULMONARY HYPERTENSIVE RATS WITH AND WITHOUT INSULIN RESISTANCE. Journal of Hypertension. 2021. 39. Supplement 1. e251-e252