Terada Kazutoyo

Affiliation and department：
Job title： Associate Professor

Research field (3)： Functional biochemistry , Molecular biology , Cell biology

Research theme for competitive and other funds (14)：

2007 - 2012 Analyses of the physiological roles of unfolded protein response
2008 - 2010 Molecular mechanism of abnormal pH-homeostasis in the lumen of acidic organele from DjA2 knock out mice
2002 - 2006 Functional analysis of chaperones in mammals
2002 - 2003 Regulation of nitric oxide (NO) synthesis and NO-induced apoptosis
2001 - 2002 Integrated analysis of hsc70-based mammalian molecular chaperone system

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Papers (70)：

Shinsei Yumoto, Haruki Horiguchi, Tsuyoshi Kadomatsu, Taichi Horino, Michio Sato, Kazutoyo Terada, Keishi Miyata, Toshiro Moroishi, Hideo Baba, Yuichi Oike. Host ANGPTL2 establishes an immunosuppressive tumor microenvironment and resistance to immune checkpoint therapy. Cancer science. 2024
Haruki Horiguchi, Tsuyoshi Kadomatsu, Tomoya Yamashita, Shinsei Yumoto, Taichi Horino, Michio Sato, Kazutoyo Terada, Keishi Miyata, Yuki Ichigozaki, Toshihiro Kimura, et al. Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy. Cancer gene therapy. 2024
Kazutoyo Terada, Motoyoshi Endo, Hiroshi Kiyonari, Naoki Takeda, Yuichi Oike. Loss of Dja2 accompanies pH deviation in lysosomes and lysosome-related organelles. Journal of cellular physiology. 2023
Haruki Horiguchi, Tsuyoshi Kadomatsu, Tomoya Yamashita, Shinsei Yumoto, Kazutoyo Terada, Michio Sato, Jun Morinaga, Keishi Miyata, Yuichi Oike. ANGPTL2 promotes immune checkpoint inhibitor-related murine autoimmune myocarditis. Communications biology. 2023. 6. 1. 965-965
Haruki Horiguchi, Tsuyoshi Kadomatsu, Keishi Miyata, Kazutoyo Terada, Michio Sato, Daisuke Torigoe, Jun Morinaga, Toshiro Moroishi, Yuichi Oike. Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis. Oncogene. 2021. 40. 1. 55-67

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MISC (34)：

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Books (9)：

Mammalian HSP40/DnaJ chaperone proteins in cytosol., In Cell Stress Proteins, Protein Reviews, Vol. 7 (ISBN: 978-0-387-39714-6)
Springer Press 2007
HSP90と癌へのシャペロン作用(翻訳)
Nature Reviews Cancer biology collection セレクト論文日本語訳集 2006
サイトゾルHSP70分子シャペロン系の働き
生化学 2005
細胞におけるHsp70シャペロン系の機能
蛋白質核酸酵素 2004
サイトゾルにおけるタンパク質のフォールディングと品質管理
細胞工学 2004

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Lectures and oral presentations (19)：

Hsc70とDjA1による変性GAPDHタンパク質の認識
(第84回日本生化学会大会 2011)
Hsc70とDjA1による基質タンパク質の認識機構
(第83回日本生化学会大会/第33回日本分子生物学会年会 2010)
An initial step of substrate recognition by Hsc70 and DjA1
(“The 3rd International Symposium on Protein Community” 2010)
An initial step of denatured protein recognition by Hsc70 and DjA1.
(CSHS " Molecular chaperones and Stress Responses" 2010)
Hsc70シャペロン系と変性タンパク質の分子間相互作用解析
(第82回日本生化学会大会 2009)

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Works (15)：

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Education (4)：

Professional career (2)：

Work history (12)：

2003 - 2010 Kumamoto University
2010 - Kumamoto University Faculty of Life Sciences
2010 - Associate Professor,Faculty of Life Sciences(Basic medicine group),Kumamoto University
2003 - 2007 Associate Professor,
2000 - 2003 Kumamoto University School of Medicine

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Awards (2)：

Association Membership(s) (3)：

日本生化学会 , 日本細胞生物学会 , 日本分子生物学会

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