Rchr
J-GLOBAL ID：200901038484918886   Update date: Feb. 01, 2024

Shimoke Koji

シモケ コウジ | Shimoke Koji
Affiliation and department：
Kansai University Faculty of Chemistry, Materials and BioengineeringDepartment of Life Science and Biotechnology

About Kansai University Faculty of Chemistry, Materials and BioengineeringDepartment of Life Science and Biotechnology


Job title： Professor
Homepage URL  (1)： http://neurobio.life-bio.kansai-u.ac.jp/
Research field  (5)： Environmental effects of chemicals ,  Molecular biology ,  Neuroscience - general ,  Green/sustainable/environmental chemistry ,  Environmental load/risk assessment
Research keywords  (9)： neuron ,  PC12 cell ,  neurite ,  bisphenol A ,  endocrine disrupting properties ,  apoptosis ,  ER stress ,  Neurotrophic factors ,  神経回路
Research theme for competitive and other funds  (12)：
  • 2016 - 2019 Analysis of the effects on neural differentiation during presence of bisphenol A
  • 2017 - 2018 琵琶湖・淀川水系における環境汚染物質ビスフェノールAの溶存量と脳神経系に対する影響の相関的比較研究
  • 2016 - 2017 琵琶湖と淀川に溶存する環境ホルモンの脳神経細胞に対する評価方法の確立
  • 2013 - 2016 The biological meaning of neurite outgrowth via bisphenol A and its receptor
  • 2013 - 2014 エピジェネティックな分子制御による神経突起伸長作用の解析
Show all
Papers (65)：
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MISC (22)：
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Patents (4)：
  • 甲虫より放出された物質の抽出方法及びその抽出物質
  • 神経変性疾患治療薬のスクリーニング方法
  • 蛹形成時の社会性維持を可能とする甲虫の飼育方法
  • 甲虫を用いた社会性に関与する生理活性物質を創出する方法
Books (7)：
  • Analysis of the role of nerve growth factor in promoting cell survival during endoplasmic reticulum stress in PC12 cells.
    Methods in Enzymology 2011
  • Prevention of apoptosis by neurotrophic factors -Contribution of pathophysilogical analysis to therapy of neurodegenerative diseases-
    2009
  • 小胞体ストレス誘導型アポトーシスとその細胞内防御機構-脳神経細胞の死による疾患とその治療戦略立案の可能性-
    理工学と技術 2007
  • Endoplasmic reticulum stress-induced apoptosis and its prevention by neurotrophins
    "New Trends in Brain Research"NOVA Science Publishers, Inc. (New York) 2006
  • PI3-キナーゼを介する神経細胞死制御シグナル
    老化と疾患 1999
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Lectures and oral presentations  (110)：
  • Analysis of nurr1 gene expression and its downstream molecular mechanism on neurite outgrowth by class I HDAC inhibitors in PC12 cells
    (2019)
  • Bisphenol A induces neurite extension in PC12 cells
    (49th Annual Meeting of Socitety for Neuroscience 2019)
  • Molecular mechanism of nurr1 gene expression and its downstream target gene expression by class I HDAC inhibitors in PC12 cells
    (2019)
  • Molecular mechanism of nurr1 gene expression and its downstream target gene expression by VPA or MS-275 in PC12 cells
    (2019)
  • The expression mechanism of nur77 gene and its downstream target gene in early stage of the forskolin-induced differentiation in PC12 cells
    (2018)
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Education (3)：
  • 1995 - 1998 Osaka University Graduate School of Science Biochemistry, docter's couse
  • 1993 - 1994 Osaka University Graduate School of Science Biochemistry, master's course
  • 1989 - 1993 Kyushu University Faculty of Science, Department of Chemistry
Professional career (1)：
  • Doctor(Sceince)
Work history (5)：
  • 2015/04 - 現在 Kansai University Faculty of Chemistry , Materials and Bioengineering
  • 2006/04 - 2015/03 Kansai University Faculty of Chemistry , Materials and Bioengineering
  • 2004/04 - 2006/03 Kansai University Faculty of Engineering
  • 2002/04 - 2004/03 Kansai University Faculty of Engineering
  • 1998/04 - 2002/03 株式会社 田辺製薬 創薬研究所 研究員
Committee career (1)：
  • 2015/04 - 現在 日本生化学会 評議員
Association Membership(s) (5)：
日本エピジェネティクス研究会 ,  北米神経科学会 ,  日本分子生物学会 ,  日本神経化学会 ,  日本生化学会
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