Research field (3)：
Pharmacology
, Pharmaceuticals - health and biochemistry
, Food sciences
Research keywords (2)：
生化学
, Biochemistry
Research theme for competitive and other funds (5)：
2004 - 2006 Research on a new oxygen radicals-eliminating system induced by aerobic physical exercise
2002 - 2004 ミトコンドリア外Coenzyme Qの還元機構とその生理的存在意義の研究
2002 - 2004 Reduction of Extra-mitochondrial Coenzyme Q and its Physiological Roles
1997 - 1998 Response in Myocytes and Change in Antioxidants Induced by Oxidative Stress
1996 - 1998 Physiological role of ubiquinone in cellular antioxidant system
Papers (5)：
Yukitoshi Mine, Takayuki Takahashi, Tadashi Okamoto. Stimulatory effects of collagen production induced by coenzyme Q10 in cultured skin fibroblasts. Journal of Clinical Biochemistry and Nutrition. 2022. 71. 1. 29-33
Yukitoshi Mine, Takayuki Takahashi, Tadashi Okamoto. Protective effects of coenzyme Q10 on cell damage induced by hydrogen peroxides in cultured skin fibroblasts. Journal of Clinical Biochemistry and Nutrition. 2021. 69. 3. 247-255
Takayuki Takahashi, Yukitoshi Mine, Tadashi Okamoto. Extracellular coenzyme Q10 (CoQ10) is reduced to ubiquinol-10 by intact Hep G2 cells independent of intracellular CoQ10 reduction. Archives of Biochemistry and Biophysics. 2019. 672. 108067-108067
Takayuki Takahashi, Yukitoshi Mine, Tadashi Okamoto. 2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) Disrupts Carbohydrate Metabolism of HeLa Cells by Adduct Formation with Intracellular Free Sulfhydryl-Groups, and Induces ATP Depletion and Necrosis. Biological and Pharmaceutical Bulletin. 2018. 41. 12. 1809-1817
Takayuki Takahashi, Yukitoshi Mine, Tadashi Okamoto. Intracellular reduction of coenzyme Q homologues with a short isoprenoid side chain induces apoptosis of HeLa cells. The Journal of Biochemistry. 2018. 163. 4. 329-339
