Rchr
J-GLOBAL ID:200901038883989959   Update date: Nov. 20, 2024

Ohno Hiroshi

オオノ ヒロシ | Ohno Hiroshi
Affiliation and department:
Job title: チームリーダー
Research theme for competitive and other funds  (53):
  • 2024 - 2026 歯周炎が惹起するInflammagingにおける口腸連関機構の解明
  • 2022 - 2025 宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究
  • 2019 - 2023 腸炎における粘膜障害治癒に関与する腸内細菌の同定とそのメカニズムの解明
  • 2019 - 2022 The impact of gut microbiota on autoimmune diseases
  • 2018 - 2021 Elucidation of oral-gut association based on Elucidation of oral-gut association based on multi-omics analyzes
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Papers (263):
  • Kazuki Okuyama, Motoi Yamashita, Artemis Koumoundourou, Christoph Wiegreffe, Michiko Ohno-Oishi, Samuel J H Murphy, Xin Zhao, Hideyuki Yoshida, Takashi Ebihara, Naoko Satoh-Takayama, et al. A mutant BCL11B-N440K protein interferes with BCL11A function during T lymphocyte and neuronal development. Nature immunology. 2024
  • Takashi Kanaya, Toshi Jinnohara, Sayuri Sakakibara, Naoko Tachibana, Takaharu Sasaki, Tamotsu Kato, Marc Riemann, Jianshi Jin, Katsuyuki Shiroguchi, Eiryo Kawakami, et al. RelB and C/EBPα critically regulate the development of Peyer's patch mononuclear phagocytes. Mucosal immunology. 2024
  • Ryohtaroh Matsumoto, Kosuke Ogata, Daisuke Takahashi, Yusuke Kinashi, Takahiro Yamada, Ryo Morita, Keisuke Tanaka, Kouya Hattori, Mayumi Endo, Yumiko Fujimura, et al. AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine. Cellular and Molecular Life Sciences. 2024. 81. 1
  • Yusuke Kinashi, Keisuke Tanaka, Shunsuke Kimura, Masato Hirota, Seiga Komiyama, Tomoko Shindo, Akinori Hashiguchi, Daisuke Takahashi, Shinsuke Shibata, Shin-Ichiro Karaki, et al. Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice. EBioMedicine. 2024. 106. 105256-105256
  • Alex Steimle, Mareike Neumann, Erica T. Grant, Stéphanie Willieme, Alessandro De Sciscio, Amy Parrish, Markus Ollert, Eiji Miyauchi, Tomoyoshi Soga, Shinji Fukuda, et al. Gut microbial factors predict disease severity in a mouse model of multiple sclerosis. Nature Microbiology. 2024
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MISC (175):
  • Hirokuni Miyamoto, Nobuhiro Kawachi, Atsushi Kurotani, Wataru Suda, Shigeharu Moriya, Arisa Tsuboi, Makiko Matsuura, Teruno Nakaguma, Chitose Ishii, Naoko Tsuji, et al. Estimation of symbiotic bacterial structure in a sustainable seagrass ecosystem on recycled management. 2022
  • Hirokuni Miyamoto, Katsumi Shigeta, Wataru Suda, Yasunori Ichihashi, Naoto Nihei, Makiko Matsuura, Arisa Tsuboi, Naoki Tominaga, Masahiko Aono, Muneo Sato, et al. Agricultural quality matrix-based multiomics structural analysis of carrots in soils fertilized with thermophile-fermented compost. 2022
  • Tadashi Takeuchi, Yumiko Nakanishi, Kazutaka Ikeda, Hiroshi Tsugawa, Wataru Suda, Yoshiko Mizuno, Nobutake Yamamichi, Makoto Arita, Masahira Hattori, Naoto Kubota, et al. Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans. DIABETES. 2020. 69
  • 山崎恭子, 山崎恭子, 中島麻由佳, 竹内麻衣, 原実生, 都野隆博, 都野隆博, 松岸葵, 松岸葵, 松川由実, et al. Periodontal disease exacerbates NAFLD via dysbiosis of gut microbiota. 腸内細菌学雑誌. 2020. 34. 2
  • Mari Tenno, Alicia Yoke Wei Wong, Mika Ikegaya, Eiji Miyauchi, Wooseok Seo, Peter See, Tamotsu Kato, Takashi Taida, Michiko Oishi-Ohno, Hiroshi Ohno, et al. Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells. Life Science Alliance. 2020. 3. 1
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Patents (1):
  • m3B遺伝子欠損非ヒト動物
Education (2):
  • 1987 - 1991 Chiba University Graduate School of Medicine
  • 1977 - 1983 Chiba University School of Medicine
Professional career (1):
  • 医学博士
Work history (9):
  • 2018/04 - 現在 RIKEN Laboratory for Intestinal Ecosystem, Center for Integrative Medical Sciences Team Leader
  • 2002/02 - 2013/03 RIKEN Research Center for Allergy and Immunology Team Leader
  • 1999/04 - 2004/03 金沢大学がん研究所教授
  • 1997/05 - 1999/03 Chiba University School of Medicine
  • 1991/04 - 1997/04 Chiba University School of Medicine Assistant Professor
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Awards (5):
  • 2021/11 - 持田記念医学薬学振興財団 持田記念学術賞 健康と病態に関わる宿主-腸内細菌相互作用の包括的理解
  • 2018 - 野口英世記念会 第61回野口英世記念医学賞 宿主-腸内細菌相互作用の総合的理解に関する研究
  • 2018 - 文部科学省 文部科学大臣表彰 科学技術賞(研究部門) 腸内環境の統合的研究
  • 2016 - ベーリンガーインゲルハイム 第53回ベルツ賞(2等賞) 宿主-腸内細菌叢相互作用
  • 2015 - 安藤スポーツ・食文化振興財団 第20回安藤百福賞大賞 腸内細菌が食物成分を分解して産生する代謝産物による 腸管免疫系制御の分子メカニズムの解明
Association Membership(s) (7):
日本癌学会 ,  日本生化学会 ,  日本分子生物学会 ,  日本細胞生物学会 ,  日本免疫学会 ,  日本消化器免疫学会 ,  腸内細菌学会
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