Rchr
J-GLOBAL ID:200901039667162990
Update date: May. 23, 2024
Shibata Naoki
シバタ ナオキ | Shibata Naoki
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://www.sci.u-hyogo.ac.jp/life/biophys1/index-j.html
Research field (1):
Structural biochemistry
Research keywords (7):
結晶化
, 構造生物学
, タンパク質
, X線結晶構造解析
, protein crystallization
, structural studies
, X-ray crystallography
Research theme for competitive and other funds (20):
- 2021 - 2024 Structural basis of activation of a novel tumor progression signaling involving Wnt signaling proteins and supression by antibodies.
- 2019 - 2020 がん細胞増殖シグナルを活性化するタンパク質複合体の構造生物学
- 2018 - 2019 ポリオール廃液から有用アルコールを効率的に産出する発酵システムのための触媒の開発
- 2014 - 2019 Molecular design of nylon hydrolase and industrial application of the enzyme
- 2014 - 2017 Production of bifunctional recognition biomolecules for a novel crystallization method
- 2013 - 2015 DIXドメインをコアとするWntシグナル伝達系複合体群の構造生物学
- 2014 - 2015 Wntシグナル伝達系因子のSUMO修飾に関する構造生物学
- 2010 - 2014 Molecular design of nylon oligomer degradation enzyme and its application to bioproduction
- 2011 - 2013 Wnt受容体共役タンパク質-細胞内Wntシグナル伝達因子複合体群の構造生物学
- 2010 - 2012 Structural studies of a chromoprotein from Pleurotus Salmoneostramineus L.Vass
- 2010 - 2012 Studies of action mechanisms of radical enzyme systems for providing new paradigms of enzyme researches
- 2006 - 2009 Structural analysis of nylon oligomer hydrolase and application to enzymatic synthesis of unnatural amides
- 2007 - 2008 Structural basis for oligomerization of Axin and degradation of β-catenin.
- 2005 - 2006 β-カテニンの分解制御を行うAxin-Dvl複合体の構造解析
- 2003 - 2004 タンパク質複合体形成を利用したカルモジュリン依存性キナーゼの結晶化と構造研究
- 2002 - 2004 Structural study of the activation mechanism of dihydrogen at the Ni-Fe active site of [NiFe] hydrogenase
- 2001 - 2003 High Resolution X-ray Study of Cofactor Dependent Enzyme and Biocatalyst Design
- 2000 - 2001 超高分解能X線結晶構造解析によるFMN結合タンパク質のサブユニット認識機構解明
- 1997 - 1998 Structure Study of Vitamin B12 enzyme, Diol Dehydratase
- Structural studies of biomacromolecules
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Papers (138):
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Seiji Negoro, Naoki Shibata, Dai-Ichiro Kato, Yusuke Tanaka, Kengo Yasuhira, Keisuke Nagai, Shohei Oshima, Yoko Furuno, Risa Yokoyama, Kaito Miyazaki, et al. X-ray crystallographic and mutational analysis of the NylC precursor: catalytic mechanism of autocleavage and substrate hydrolysis of nylon hydrolase. The FEBS journal. 2023
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Naoki Shibata, Tetsuo Toraya. Structural basis for activation of cobalt-carbon bond and control of adenosyl radical in coenzyme B12 catalysis. Chembiochem : a European journal of chemical biology. 2023. e202300021
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Naoki Shibata, Yoshiki Higuchi, Bernhard Kräutler, Tetsuo Toraya. Structural Insights into the Very Low Activity of the Homocoenzyme B12 Adenosylmethylcobalamin in Coenzyme B12 -Dependent Diol Dehydratase and Ethanolamine Ammonia-Lyase. Chemistry (Weinheim an der Bergstrasse, Germany). 2022. 28. 65. e202202196
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Tetsuo Toraya, Takamasa Tobimatsu, Koichi Mori, Mamoru Yamanishi, Naoki Shibata. Coenzyme B12-dependent eliminases: Diol and glycerol dehydratases and ethanolamine ammonia-lyase. Methods in enzymology. 2022. 668. 181-242
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Tetsuo Toraya, Takamasa Tobimatsu, Naoki Shibata, Koichi Mori. Reactivating chaperones for coenzyme B12-dependent diol and glycerol dehydratases and ethanolamine ammonia-lyase. Methods in enzymology. 2022. 668. 243-284
more...
MISC (65):
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柴田直樹, 樋口芳樹, 虎谷哲夫. O2により不活性化されたラジカルB12酵素ジオールデヒドラターゼの構造解析と補酵素分解物の同定. 第468回ビタミンB研究協議会. 2022
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根来誠司, 武尾正弘, 柴田直樹, 樋口芳樹, 加藤太一郎, 重田育照. ナイロン分解酵素NylB の構造進化,触媒機構とアミド合成への応用. 月刊バイオインダストリー. 2019
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Yamanaka Masaru, Hoshizumi Makoto, Nagao Satoshi, Nakayama Ryoko, Shibata Naoki, Higuchi Yoshiki, Hirota Shun. Formation and carbon monoxide-dependent dissociation of Allochromatium vinosum cytochrome c' oligomers using domain-swapped dimers. 2017
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Kinugasa Ryo, Hada Keigo, Tanimoto Yuki, Takehara Ikki, Shibata Naoki, Kato Daiichiro, Takeo Masahiro, Negoro Seiji. 3P-046 Effect of amino acid substitution on the thermostability of nylon hydrolase. 2015. 67. 282-282
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Y. Higuchi, M. Akter, C. Inoue, Y. Shomura, N. Shibata, K. Inaka, K. Kataoka, T. Sakurai, K. Komori. Preparation of single crystals of Multicopper oxidases for neutron diffraction study. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S324-S324
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Books (3):
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プラスチックのリサイクルと再生材の改質技術
株式会社技術情報協会 2023 ISBN:9784867980101
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食品・バイオにおける最新の酵素応用, IIIバイオ産業への酵素応用編
シーエムシー出版 2019
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日本の結晶学 (II)
日本結晶学会 2014
Professional career (1):
- (BLANK) (Osaka University)
Awards (1):
- 2003/12 - 日本結晶学会 平成15年度日本結晶学会賞進歩賞
Association Membership(s) (5):
日本蛋白質科学会
, 日本放射光学会
, 日本生化学会
, 日本生物物理学会
, 日本結晶学会
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