Rchr

J-GLOBAL ID：200901039699519237 Update date: Mar. 25, 2024

Yoshimura Atsutoshi

ヨシムラアツトシ | Yoshimura Atsutoshi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.de.nagasaki-u.ac.jp/education/dept_perio.html

Research field (1)： Conservative dentistry and endodontics

Research keywords (2)：歯周病学 , Periodontology

Research theme for competitive and other funds (31)：

2021 - 2024 β-シクロデキストリンの包接および除放作用を応用した新規根管貼薬剤の開発
2020 - 2023 歯周病によるNLRP3インフラマソーム活性化が全身疾患に及ぼす影響
2019 - 2022 Effect of HMGB1 on bone resorption induced by traumatic occlusion
2018 - 2021 Bone absorbent promotion by cholesterol crystals deposited in the apex and inhibition by cyclodexttin
2016 - 2019 歯石によるインフラマソームの活性化機構の解明とその阻害薬を用いた歯周組織破壊の抑制

2015 - 2018 Experimental pathological study on prevention of periodontitis and periimplantitis caused by drugs

2014 - 2018 The role of capases in clearance of periodontal pathogens and regulation of inflammatory responses.

2012 - 2016 An experimental study of mechanism of periodontal and peri-implant tissue destruction.

2011 - 2015 The regulation of periodontal inflammation based on the inflammasomes activated by periodontal pathogens.

2012 - 2014 Toll様受容体を標的とした歯周組織の炎症制御に関する基礎的研究

2008 - 2010 Evaluation of the periodontal disease activity measuring the ability of dental plaque to activate innate immune system

2008 - 2010 Biological responses that eliminate invasive bacteria in the periodontal cells

2007 - 2008 A study on acceleration of bone resorption by immunized cells

2006 - 2008 Mail Medicine using Fingertip Plasma for Screening and Monitoring Periodontitis

2006 - 2007 Study for gignipain-related adhesins of Periodontal pathogen, Porphyromonas gingivalis for its platelet aggregation activity

2005 - 2007 Molecular Mechanisms of Interaction between Periodontitis and Cardiovascular and Bone Metabolic Disorders

2004 - 2007 Analysis of the mechanism for a periodontopathic bacteria P. gingivalis to escape from innate immune system

2004 - 2005 A basic research on coupling factors between bone resorption and bone formation

2002 - 2003 Tlr2およびTlr4遺伝子突然変異の歯周病発症に与える影響についての解析

2001 - 2002 Structural analysis of lipope microbes responsible for binding to Toll-like receptors

2001 - 2002 Immunohistlogical study of mouse periodontal burst model

2000 - 2001 歯周病患者末梢血白血球の歯周病原性細菌内毒素に対する応答とTLR2の発現について

1996 - 1997 A study for establishment of judging periodontal disease activity

1996 - 1997 Immunohistological study on infiltration of periodontopathic bacterial lipopolysaccharide into gingiva and lesional lymph node.

1996 - 1996 歯周病患者末梢血多形核白血球のLPS刺激により炎症性サイトカイン産生量の比較

1995 - 1995 歯周病原菌由来LPSによるヒト多形核白血球のIL-1raの産生誘導について

1994 - 1995 Histopathological study with in situ hybridization on cytokine producing cells in bone ersorption

1994 - 1994 SCID-huマウスを用いた実験的歯周炎誘発モデルの開発とその発症機序の解析

1993 - 1994 Experimental study of the effect of T cell on alveolar bone resorption induced by bacterial endotoxin

1989 - 歯周組織の感染防御に関する免疫学的研究

1989 - Immunological study on host dentense system in periodontal tissue.

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Papers (101)：

Shinji Matsuda, Tomoaki Shintani, Tsuyoshi Miyagawa, Hiromichi Yumoto, Yasutaka Komatsu, Nanae Dewake, Takanori Iwata, Takatoshi Nagano, Toshiya Morozumi, Ryoma Goto, et al. Effect of Periodontal Treatment on Reducing Chronic Inflammation in Systemically Healthy Patients With Periodontal Disease. The American journal of medicine. 2024. 137. 3. 273-279
Jun Miyata, Hirotomo Yamanashi, Shin-Ya Kawashiri, Sakiko Soutome, Kazuhiko Arima, Mami Tamai, Fumiaki Nonaka, Yukiko Honda, Masayasu Kitamura, Koji Yoshida, et al. Profile of Nagasaki Islands Study (NaIS): A Population-Based Prospective Cohort Study on Multi-disease. Journal of epidemiology. 2023
Hidetaka ISHIZAKI, Takashi MATSUURA, Shizuka YAMADA, Atsutoshi YOSHIMURA. Overview, Scouting and Treatment of Mesio-buccal Root Second Canal (MB2) of Maxillary Molar, Disto-lingual Root Canal (DL) and Middle Mesial Root Canal (MM) of Mandibular Molar. The Japanese Journal of Conservative Dentistry. 2023. 66. 1. 6-22
Takashi Matsuura, Megumi Mae, Masayuki Ohira, Yumiko Mihara, Yasunori Yamashita, Kouji Sugimoto, Shizuka Yamada, Atsutoshi Yoshimura. The efficacy of a novel zinc-containing desensitizer CAREDYNE Shield for cervical dentin hypersensitivity: a pilot randomized controlled trial. BMC Oral Health. 2022. 22. 1
Hidetaka ISHIZAKI, Shizuka YAMADA, Atsutoshi YOSHIMURA. Overview of Lateral Canals in Endodontic Treatment and Its Treatment Strategies. The Japanese Journal of Conservative Dentistry. 2022. 65. 5. 257-268

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MISC (92)：

松田真司, 菅谷勉, 加藤幸紀, 根本英二, 竹内康雄, 山下慶子, 沼部幸博, 西田哲也, 小方頼昌, 申基哲, et al. 全身性疾患への影響を考慮した新たな歯周病重症度検査項目の策定~学会主導型多施設臨床研究~第二報. 日本歯周病学会会誌(Web). 2023. 65
松田真司, 菅谷勉, 加藤幸紀, 根本英二, 竹内康雄, 喜田大智, 沼部幸博, 西田哲也, 小方頼昌, 申基哲, et al. 全身性疾患への影響を考慮した新たな歯周病重症度検査項目の策定学会主導型多施設臨床研究. 日本歯周病学会会誌. 2022. 64. 秋季特別. 112-112
前めぐみ, Alam Mohammad Ibtehaz, 吉村篤利. 歯石刺激後のマウスマクロファージによりNLRP3インフラマソームを介して産生されるIL-1βおよびIL-18が破骨細胞形成に及ぼす影響. 日本歯周病学会会誌. 2022. 64. 春季特別. 115-115
松田真司, 菅谷勉, 加藤幸紀, 根本英二, 竹内康雄, 喜田大智, 沼部幸博, 西田哲也, 小方頼昌, 申基哲, et al. 全身性疾患への影響を考慮した新たな歯周病重症度検査項目の策定~学会主導型多施設臨床研究~. 日本歯周病学会会誌(Web). 2022. 64
石崎秀隆, 中園史子, 山田志津香, 吉村篤利. Causes of Endodontic Failure of Isthmus-containing Root canals, and Treatment Strategies. 日本歯科保存学雑誌(Web). 2022. 65. 1

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Books (15)：

ザ・ペリオドントロジー = The periodontology
永末書店 2023 ISBN:9784816014215
歯周病およびインプラント周囲組織の疾患と状態に関する新分類 : アメリカ歯周病学会(AAP)/ヨーロッパ歯周病連盟(EFP)共催2017ワールドワークショップ会議録
クインテッセンス出版 2020 ISBN:9784781207735
臨床歯周病学
医歯薬出版 2020 ISBN:9784263458440
ザ・ペリオドントロジー = The periodontology
永末書店 2019 ISBN:9784816013584
Periodontics for Special needs Patients 障害者・有病者の歯周治療
デンタルダイヤモンド社 2017 ISBN:9784885103643

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Lectures and oral presentations (146)：

The vitality and potential of dental pulp - a case report -
(The 11th Annual Congress,German Society of Endodontology and Dental Traumatology 2022)
Effectiveness of antimicrobial photodynamic therapy in the periodontal maintenance phase
(The 108th Annual Meeting of the American Academy of Periodontology in collaboration with the Japanese Society of Periodontology 2022)
Osteoclastogenic and anti-osteoclastogenic cytokines induced by dental calculus
(The 108th Annual Meeting of the American Academy of Periodontology in collaboration with the Japanese Society of Periodontology 2022)
The vitality and potential of dental pulp
(The 20th ESE Biennial Congress, European Society of Endodontology 2022)
全身性疾患への影響を考慮した新たな歯周病重症度検査項目の策定学会主導型多施設臨床研究
(日本歯周病学会会誌 2022)

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Works (23)：

歯石によるインフラマソームの活性化機構の解明とその阻害薬を用いた歯周組織破壊の抑制
吉村篤利 2016 - 2018
歯周組織およびインプラント周囲組織の破壊機序解明に関する実験病理学的研究
2012 - 2015
Toll様受容体を標的とした歯周組織の炎症制御に関する基礎的研究
2012 - 2015
歯周病原細菌によるインフラマソーム活性化機構に着目した歯周炎症反応の制御
2011 - 2014
細胞内侵入細菌の排除機構の解析とペプチドグリカンを標的とした歯周治療法の開発
2008 - 2011

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Education (4)：

1989 - 1993 Nagasaki University Graduate School of Dentistry
- 1993 Nagasaki University Graduate School, Division of Dental Research
1983 - 1989 Nagasaki University School of Dentistry
- 1989 Nagasaki University Faculty of Dentistry

Professional career (1)：

(BLANK) (Nagasaki University)

Work history (14)：

2018/04 - 現在 Nagasaki University Graduate School of Biomedical Sciences Department of Periodontology and Endodontology Professor
2018/04 - 現在 Nagasaki University Graduate School of Biomedical Sciences
2008/03 - 2018/03 Nagasaki University Graduate School of Biomedical Sciences Department of Periodontology Associate Professor
2008/03 - 2018/03 Nagasaki University Graduate School of Biomedical Sciences
2002/10 - 2008/02 Nagasaki University School of Medicine

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Committee career (24)：

2023/04 - 現在日本歯周病学会編集委委員会副委員長
2023/04 - 現在日本歯科保存学会認定歯科衛生士審査委員会委員
2023/04 - 現在日本歯科保存学会渉外委員会委員長
2021/04 - 現在日本歯科保存学会編集委員会委員
2021/04 - 現在日本歯周病学会国際交流委員会委員長

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Awards (2)：

2018/11 - The 104th Annual Meeting of the American Academy of Periodontology in collaboration with the Canadian Academy of Periodontology, the Japanese Academy of Clinical Periodontology, and the Japanese Society of Periodontology The Poster Award IL-1β induced by dental calculus promotes osteoclastogenesis in RAW-D cells
2003 - 日本歯周病学会学術賞

Association Membership(s) (10)：

International Association for Dental Research , 日本エンドトキシン・自然免疫研究会 , Japan Endodontic Association , JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH , JAPANESE DENTAL EDUCATION ASSOCIATION , The International Academy of Periodontology , The International Endotoxin and Innate Immunity Society , 日本口腔インプラント学会 , 日本歯科保存学会 , 日本歯周病学会

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