Rchr
J-GLOBAL ID:200901039877381783
Update date: Nov. 20, 2024
Chiba Yoshihiko
チバ ヨシヒコ | Chiba Yoshihiko
Affiliation and department:
Job title:
Professor
Research field (3):
Pharmacology
, Pharmaceuticals - health and biochemistry
, Functional biochemistry
Research keywords (8):
アレルギー性鼻炎
, 平滑筋
, 気道過敏性
, 気管支喘息
, Allergic rhinitis
, Smooth muscle
, Airway hyperresponsiveness
, Allergic bronchial asthma
Research theme for competitive and other funds (23):
- 2024 - 2027 スギ花粉症時の鼻粘膜過敏性形成におけるペリオスチンの病態生理学的意義の同定
- 2024 - 2027 Identification of untranslated RNAs and their target molecular species involved in airway hyperresponsiveness after lung transplantation
- 2021 - 2024 肺移植術後の気道過敏性亢進に関与する非翻訳RNAとその標的分子種の同定
- 2018 - 2021 肺移植術後の気道過敏性亢進に関与する非翻訳RNAとその標的分子種の同定
- 2016 - 2019 全身麻酔薬による臓器保護作用に関与するマイクロRNAおよびその標的遺伝子の同定
- 2015 - 2018 肺移植術後の気道過敏性亢進メカニズムの解明
- 2015 - 2017 Possible involvement of epigenomic alterations in the development of bronchial smooth muscle hyperresponsiveness in allergic asthma
- 2013 - 2015 Identification of micro RNA involved in organ protective effects of general anesthetics.
- 2012 - 2014 Mechanism of airway hyperresponsiveness after lung transplantation
- 2011 - 2013 Role of miRNAs in the development of bronchial smooth muscle hyperresponsiveness in allergic asthma
- 2009 - 2011 Mechanism of airway hyperresponsiveness after lung transplantation
- 2008 - 2010 Mechanisms involved in the development of bronchial smooth muscle hyperresponsiveness in allergic bronchial asthma
- 2008 - 2009 マイクロRNA (miRNA) をターゲットとした新規アレルギー性気管支喘息治療薬の開発
- 2006 - 2007 Mechanisms for the induction of bronchial smooth muscle hyperresponsiveness in allergic bronchial asthma
- 2006 - 2007 Identification of transcription factors of contractile element of bronchial smooth muscle and its change in activity at airway hyperresponsiveness
- 2003 - 2005 Studies on change in airway hyperresponsiveness at bronchial asthma using the technique of RhoA gene manipulation
- 2001 - 2002 (アレルギー性気管支喘息発症機序の解明)
- 2000 - 2002 Change in RhoA activating mechanism in airway hyperresponsive bronchial smooth muscle.
- 2000 - 2001 (アレルギー性気管支喘息時の気道過敏性発症機序の解明)
- 2000 - 2001 気道過敏性時の摘出気管支平滑筋収縮におけるカルシウム感受性亢進機序の解明
- 1997 - 1998 抗原誘発気道過敏性時の摘出気管支平滑筋収縮におけるカルシウム感受性の変化
- アレルギ-性気管支喘息時の気道過敏性発症機序の追究
- Mechanisms involved in the pathogenesis of airway hyperresponsiveness in allergic asthma.
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Papers (161):
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Yoshihiko Chiba, Yamato Yamane, Tsubasa Sato, Wataru Suto, Motohiko Hanazaki, Hiroyasu Sakai. Extracellular acidification attenuates bronchial contraction via an autocrine activation of EP2 receptor: Its diminishment in murine experimental asthma. Respiratory physiology & neurobiology. 2024. 324. 104251-104251
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Yu Miyauchi, Miho Kiyama, Shinki Soga, Hayato Nanri, Takayuki Ogiwara, Shiori Yonamine, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, et al. Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin. Biological & pharmaceutical bulletin. 2024. 47. 11. 1846-1850
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Fumiko Takenoya, Junko Shibato, Michio Yamashita, Ai Kimura, Satoshi Hirako, Yoshihiko Chiba, Naoko Nonaka, Seiji Shioda, Randeep Rakwal. Transcriptomic (DNA Microarray) and Metabolome (LC-TOF-MS) Analyses of the Liver in High-Fat Diet Mice after Intranasal Administration of GALP (Galanin-like Peptide). International journal of molecular sciences. 2023. 24. 21
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Ken Sato, Yoshida Satoshi, Yu Miyauchi, Fumiaki Sato, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, Hiroyasu Sakai. Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle. Biochimica et biophysica acta. Molecular basis of disease. 2023. 1870. 1. 166877-166877
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花崎 元彦, 千葉 義彦, 倉橋 清泰. 低酸素条件下培養細胞を用いた肺移植後気道過敏性に関与する非翻訳RNAの同定. 国際医療福祉大学学会誌. 2023. 28. 抄録号. 159-159
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MISC (278):
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木山美穂, 宮内優, 里史明, 今理紗子, 五十嵐信智, 千葉義彦, 細江智夫, 酒井寛泰. Effect of cisplatin on changing in the gene expression of collagen and elastin in dermal fibroblast. 日本薬学会年会要旨集(Web). 2024. 144th
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南里駿仁, 曽我眞希, 木山美穂, 荻原隆行, 宮内優, 今理紗子, 五十嵐信智, 千葉義彦, 細江智夫, 酒井寛泰. Examination of endoplasmic reticulum stress response in skeletal muscles of mice treated with various anticancer drugs. 日本薬学会年会要旨集(Web). 2024. 144th
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染谷柚杏, 千種佑也, 曽我眞希, 南里駿仁, 木山美穂, 荻原隆行, 宮内優, 千葉義彦, 今理紗子, 五十嵐信智, et al. Investigation of E3 ubiquitin ligase with altered gene expression during cisplatin-induced muscle atrophy. 日本薬学会年会要旨集(Web). 2024. 144th
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荻原隆行, 宮内優, 曽我眞希, 南里駿仁, 木山美穂, 佐藤健, 今理紗子, 五十嵐信智, 千葉義彦, 細江智夫, et al. Downregulation of Fndc5/Irisin in skeletal muscle during cisplatin-induced muscle atrophy. 日本薬学会年会要旨集(Web). 2024. 144th
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曽我眞希, 南里駿仁, 木山美穂, 荻原隆行, 宮内優, 千葉義彦, 今理紗子, 五十嵐信智, 細江智夫, 酒井寛泰. Upregulation of ER stress response-related chaperones and ERAD-related genes during cisplatin-induced muscle atrophy. 日本薬学会年会要旨集(Web). 2024. 144th
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Professional career (1):
Work history (6):
Committee career (5):
- 2020/09 - 現在 Editorial Board of Allergies
- 2017/04 - 現在 International Journal of Molecular Sciences Editor
- 2012/01 - 現在 Editorial Board of Dataset Papers in Pharmacology
- 2012/01 - 現在 American Physiological Society Editorial Board of Am. J. Physiol. Lung Cell. Mol. Physiol.
- 2008/04 - 2012/03 Japanease Pharmacological Society Advisory Board of J. Pharmacol. Sci.
Awards (5):
- 2020/08 - 日本平滑筋学会 日本平滑筋学会 Journal of Smooth Muscle Research 優秀論文賞 (Corresponding author)
- 2015/08 - 日本平滑筋学会 Journal of Smooth Muscle Research 優秀論文賞 (共著)
- 2010/07 - 日本平滑筋学会 2009年Best Download賞(原著論文の部)
- 2009/07 - 日本平滑筋学会 2008年Best Download賞(原著論文の部)
- 1999/05 - 星薬科大学 大谷賞
Association Membership(s) (8):
日本アロマセラピー学会
, American Thoracic Society
, American Physiological Society
, 日本平滑筋学会
, 気道過敏性研究会
, 日本アレルギ-学会
, 日本薬学会
, 日本薬理学会
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