Koji Harada

2015 - 2018 Development of new oral cancer treatments focused on mTOR inhibition leading to the anti-aging prevention and the healthy life-span extension

2015 - 2017 Development of new predictive factors for malignant alteration of oral cancer by the functional analysis of the factors in regard to loss of anchorage dependence.

2014 - 2017 Development of the new therapeutic strategy for recurrence/metastatic oral cancer -toward natural life with oral cancer-

2012 - 2015 Development of a novel functional preservation therapy against advanced, recurrent or unresectable oral cancers.

2009 - 2011 Bone regeneration procedure with tongue muscle-derived stem cell

2009 - 2011 Identification of new predictive factors for chemo-radiation against oral cancers and setting of individualized medicine based on their expressions

2007 - 2008 Development of the therapy for oral cancer by S-1 and proteasome inhibitor in combination with concurrent radiotherapy

2005 - 2006 Development of molecular targeting therapy against stability of p27^<Kip1> protein in oral squamous cell carcinoma.

2002 - 2005 Toll-like receptor 4 signaling : Enhancement of therapeutic effect of anti-cancer drugs and radiation in oral Cancer

2003 - 2004 Development of molecular targeting therapy against p27^<Kip1> in oral squamous cell carcinoma.

2002 - 2002 口腔癌細胞における抗癌剤タキソテールと分化誘導剤ベスナリノン併用の抗癌効果の検索

2001 - 2002 ヒト口腔扁平上皮癌における予後因子p27^<Kip1>発現と浸潤・転移抑制との関連性

2001 - 2002 The correlation between TGF-b3 and HGF/SF in the process of fusion of secondary palatal shelves

1999 - 2000 The role of c-Met oncogene expression in the secondary palate shelves adhesion process.

1999 - 2000 Relationship between p27^<Kip1> expression and tumor differention and prognosis in human oral squamous cell carcinoma.

1995 - 1995 ヒト口腔扁平上皮癌におけるLe^Y抗原の発現と腫瘍分化

P27^Kip1発現誘導性抗癌剤の開発に関する研究

ヒト口腔扁平と皮癌における予後因子P27^Kip1発現と浸潤・転移抑制との関連性

頭頚部癌に対するプラスミドベクター電気穿孔法を用いた遺伝子治療法の開発

ヒト口腔扁平上皮癌におけるp21 cipl/WAFlの発現動態と予後

Research on development of anti cancer drug with inducing P27^Kip1