Research field (3)：
Dermatology
, Medical biochemistry
, Molecular biology
Research keywords (6)：
分子生物学
, 人類遺伝学
, 皮膚科学
, Molecular Biology
, Human Genetics
, Dermatology
Research theme for competitive and other funds (17)：
2022 - 2025 円形脱毛症患者とモデルマウスを用いたサブタイプ別診断と治療法開発
2016 - 2019 Identification of alopecia areata gene by GWAS (3rd stage)
2015 - 2018 Exploration of psoriasis-susceptibility variants in germline and somatic cells by exome sequencing
2014 - 2016 Darier disease- possible therapeutic approach for ultraviolet B-induced aggravation.
2013 - 2016 An attempt to identify a gene for alopecia areata (2nd phase)
2010 - 2012 Genomic analysis and identification of susceptible genes for alopecia areata
2005 - 2006 Analysis of promoter regions in Hailey-Hailey disease and Darier's disease genes (2^<nd> report)
2003 - 2004 Analysis of promoter regions in Hailey-Hailey disease and Darier's disease genes.
2002 - 2004 Pathogenesis of vitiligo vulgaris : oxidative stress in the achromatic lesion.
2000 - 2001 Functional analysis of Darier disease gene and Hailey-Hailey disease gene
1999 - 2001 The multiple case studies of congenital ichthyosiform erythroderma in Japan ; investigation for their diagnosis, pathogenesis and treatment.
1998 - 1999 An attempt to identify the Darier's disease gene and to clarify its function
1997 - 1998 Biological roles of peptidylarginine deiminase in the pathogenic mechanisms of keratin deseases : molecular biological approach
1996 - 1997 CONSTRUCTION OF THE PHYSICAL MAP AT DARIER DISEASE GENE REGION ON CHROMOSOME 12Q AND AN ATTEMPT TO DETECT THE GENOMIC DELETION IN THIS REGION ON THE DNA OF PATIENTS.
1989 - 1990 正常および悪性角化細胞の遊走能に及ぼす各種生理活性物質の効果について
角化症、水疱症、乾癬、アトピー性皮膚炎、円形脱毛症
Functional analysis of the genes for Darier disease and Hailey-Hailey disease
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Papers (210)：
Toru Kimitsu, Seiji Kamijo, Tomoko Yoshimura, Yurie Masutani, Saya Shimizu, Keiko Takada, Punyada Suchiva, Hideoki Ogawa, Ko Okumura, Shigaku Ikeda, et al. Antigen Protease Activity on Intact or Tape-Stripped Skin Induces Acute Itch and T Helper Sensitization Leading to Airway Eosinophilia in Mice. JID Innovations. 2024. 4. 1. 100239-100239
Tomoko Yoshimura, Seiji Kamijo, Saori Ichikawa, Toru Kimitsu, Yurie Masutani, Saya Shimizu, Keiko Takada, Takasuke Ogawa, Mitsutoshi Tominaga, Kenji Takamori, et al. Antigen protease activity with a detergent induces severe skin inflammation with itch and robust Th17/Th22 differentiation in mice. The Journal of investigative dermatology. 2023
Jonghun Kim, Toshio Hasegawa, Kurisu Tada, Yuki Uehara, Yukiko Fukui, Ayako Nakamura, Satomi Takei, Satoshi Mitarai, Akio Aono, Shigaku Ikeda. A Systemic Lupus Erythematosus Patient with Cutaneous Mycobacterium haemophilum Infection under Belimumab Treatment: A Case Report. Annals of dermatology. 2023. 35. Suppl 1. S63-S66
Hai Le Thanh Nguyen, Ge Peng, Juan Valentin Trujillo-Paez, Hainan Yue, Risa Ikutama, Miho Takahashi, Yoshie Umehara, Ko Okumura, Hideoki Ogawa, Shigaku Ikeda, et al. The Antimicrobial Peptide AMP-IBP5 Suppresses Dermatitis-like Lesions in a Mouse Model of Atopic Dermatitis through the Low-Density Lipoprotein Receptor-Related Protein-1 Receptor. International Journal of Molecular Sciences. 2023. 24. 6. 5200-5200
- 1987 Juntendo University Graduate School, Division of Medicine
- 1982 Juntendo University Faculty of Medicine
- 1982 Juntendo University Faculty of Medicine
Professional career (1)：
PhD
Work history (9)：
1993 - 1995 Postdoctral fellow,
1993 - 1995 Postdoctral fellow,
1995 - Research Associate Dermatologist,
1995 - Reseach associate Dermatologist,
University of California at San Francisco.
Department of Dermatology,
University of California at San Francisco.
Department of Dermatology,
Juntendo University Professor and Chairman
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Committee career (1)：
1996 - 日本研究皮膚科学会 評議員
Awards (2)：
1993 - Dermatology Foundation Research Fellowship
1993 - Dermatology Foundation Research Fellowship
Association Membership(s) (8)：
American Academy of Dermatology
, 日本乾癬学会
, 日本研究皮膚科学会
, 日本皮膚科学会
, American Academy of Dermatology
, Japanese Society for Psoriasis Research
, Japanese Society for Investigative Dermatology
, Japanese Dermatological Association
