Oho Takahiko

2017 - 2020 Analysis of induction mechanism of atherosclerosis by oral biofilm bacteria-virulence caused by the mixture of diverse bacterial species

2014 - 2017 Involvement of innate immune factor gp-340 in atherosclerosis caused by oral bacteria

2014 - 2017 The evaluation of oral health status with perioperative head and neck cancer patients -psychological approach and bacterial assessment-

2014 - 2017 Experimental analysis of induction mechanism of atherosclerosis by human oral bacteria

2011 - 2013 Development of evaluation system for systemic infectious disease by oral bacteria based on the adherence to host tissues

2011 - 2013 Invasive Streptococcus mutans induces inflammatory cytokine production of human aortic endothelial cells via regulation of TLR2 and NOD2

2011 - 2012 Interactionbetween salivary proteins andoral bacteria: determinants for bacterial adherence and aggregation

2009 - 2011 Development of infection mechanism of culture-negative endocarditis

2009 - 2010 口腔細菌のバイオフィルム形成因子の発現は唾液タンパク質によって制御されるか?

2008 - 2010 Experimental analysis of the induction mechanism of atherosclerosis by oral biofilm bacteria as a possible new risk factor

2008 - 2010 Development of protection for systemic and oral infection by control of oral microbes.

2007 - 2009 Development of preventive measures against systemic diseases caused by oral biofilm

2006 - 2007 Development of novel treatment for systemic infectious disease using salivary protein that inhibits bacterial

2006 - 2007 Clarification of relationship among psychological stress, gastro-oesophageal reflux, sleep bruxism, and salivary flow

2006 - 2007 唾液タンパク質由来ペプチドを用い新しい口腔ケア方法の開発

2005 - 2006 Influence of dental plaque on general health condition-Animal model experiments-

2005 - 2006 Experimental aspiration pneumonia induced by human supragingival dental plaque in mice

2003 - 2004 Study on the pathogenicity of halitosis-causing agents and development of new method for the treatment

2003 - 2003 口腔局所のアセトアルデヒド(発がん物質)産生因子の解明

2000 - 2003 Development of bovine milk antibody to prevent dental caries

2001 - 2002 Development of new method for the diagnosis and treatment of halitosis on several odor-causing agents

2001 - 2002 Development of new method for the eradication of etiological organism of dental caries using bovine milk containing antibodies against virulence factors of the organism and the adherence-inhibiting component.

1999 - 2000 Development of new method for the treatment of halitosis using molecular biological technique

1997 - 1998 Inhibitory effects of antibodies against cell surface protein antigen PAc-glucosyltransferase fusion proteins derived from Streptococcus mutans on the induction of dental caries

1995 - 1997 Development of Immunological Procedure for Prevention of Dental Caries Using Fusion Protein of Colonization Factors

1995 - 1997 Development of Oral Diagnosis Using Rapid and Simple Quantitative Gene Amplification of Oral Pathogens

1992 - 1994 Development of immunological method for prevention of dental caries using genetic engineering

1992 - 1992 レーザー照射エナメル質におよぼすヒト唾液中各成分の作用についての研究

1990 - 1992 EXPERIMENTAL STUDY ON THE MECHANISM OF ACQUIRED ACID RESISTANCE OF HUMAN DENTAL ENAMEL BY LASER IRRADIATION