Rchr
J-GLOBAL ID：200901040510884531
Update date: Jul. 23, 2024
Asano Kenichi
アサノ ケンイチ | Asano Kenichi
Affiliation and department：
Job title：
Professor
Research field (2)：
Pathobiochemistry
, Immunology
Research keywords (7)：
自然免疫
, Macrophage
, 組織修復
, 感染防御
, Immunology
, ワクチン
, Nephrology
Research theme for competitive and other funds (15)：
- 2022 - 2027 Self-referential immune perception
- 2022 - 2027 自己成分変動に伴う自然免疫細胞産生経路の変化とその生理的意義
- 2021 - 2024 Ym1陽性単球由来マクロファージによる肝線維症の進展機序解明
- 2020 - 2024 がん免疫におけるマクロファージの役割に関する包括的な理解と診断・治療への応用
- 2021 - 2024 制御性単球の分化機構解明と炎症性腸疾患に対する治療応用
- 2017 - 2020 Immune regulation by dead intestinal epithelial cells
- 2016 - 2020 The significance of macrophages in several diseases
- 2016 - 2019 Search of the new biomarkers reflecting lymph node macrophage function and its application to molecular pathology
- 2014 - 2019 Mechanisms of immunoregulation by dead cell clearance
- 2014 - 2017 Regulation of Mucosal Immunity by CD169 Macrophages
- 2013 - 2015 CD169陽性マクロファージの分化制御機構の解明
- 2011 - 2015 腸管センチネル細胞を標的とした炎症性腸疾患治療法の開発
- 2011 - 2014 The role of CD169 macrophages in anti-tumor immunity induced by dead tumor cells
- 2009 - 2011 Clearance of Dead Tumor Cells and Tumor Immunity
- 2002 - Mechanisms of apoptotic cell engulfment by phagocyte. A
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Papers (52)：
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Ayaka Iwata, Juri Maruyama, Shibata Natsuki, Akira Nishiyama, Tomohiko Tamura, Minoru Tanaka, Shigeyuki Shichino, Takao Seki, Toshihiko Komai, Tomohisa Okamura, et al. Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice. Communications biology. 2024. 7. 1. 681-681
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Ryosuke Hiranuma, Ryota Sato, Kiyoshi Yamaguchi, Satoshi Nakamizo, Kenichi Asano, Takuma Shibata, Ryutaro Fukui, Yoichi Furukawa, Kenji Kabashima, Kensuke Miyake. Aberrant monocytopoiesis drives granuloma development in sarcoidosis. International immunology. 2024
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Kenichi Asano, Kenta Kikuchi, Miki Takehara, Manami Ogasawara, Yuki Yoshioka, Kie Ohnishi, Ayaka Iwata, Shigeomi Shimizu, Masato Tanaka. Identification of small compounds that inhibit multiple myeloma proliferation by targeting c-Maf transcriptional activity. Biochemical and Biophysical Research Communications. 2023. 684. 149135-149135
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Toshiki Anami, Cheng Pan, Yukio Fujiwara, Yoshihiro Komohara, Hiromu Yano, Yoichi Saito, Masamichi Sugimoto, Daiko Wakita, Takanobu Motoshima, Yoji Murakami, et al. Dysfunction of sinus macrophages in tumor-bearing host induces resistance to immunotherapy. Cancer Science. 2023
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Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto, et al. The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. Cell Reports. 2023. 42. 3. 112165-112165
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Patents (6)：
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免疫調節作用を有する単球細胞及びその使用方法
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がんの予防および/または治療のための医薬組成物
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CCL8による免疫細胞の動員が関与する炎症を抑制するための組成物
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多発性骨髄腫の処置のための医薬組成物
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炎症性腸疾患を抑制する抗体および該抗体を含む医薬組成物
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Education (2)：
- 2002 - 2006 Tokyo Medical and Dental University Graduate School of Medicine
- - 1999 Tokyo Medical and Dental University Faculty of Medicine
Professional career (1)：
Work history (6)：
Association Membership(s) (6)：
Japanese Society of Nephrology
, 日本Cell Death学会
, 日本生化学会
, 日本分子生物学会
, 日本免疫学会
, 日本内科学会
