Rchr
J-GLOBAL ID：200901041456477859   Update date: Jun. 08, 2024

Takenaka Yasuhiro

タケナカ ヤスヒロ | Takenaka Yasuhiro
Affiliation and department：
Nippon Medical School

About Nippon Medical School


Other affiliations (1)：
  • Saitama Medical University
Homepage URL  (1)： https://www.nms.ac.jp/college/schoolroom/kisoigaku/seitaitougyogaku/kenkyunaiyou.html
Research field  (5)： Functional biochemistry ,  Applied biochemistry ,  Evolutionary biology ,  Cell biology ,  Molecular biology
Research theme for competitive and other funds  (6)：
  • 2024 - 2027 老齢マウス心筋細胞における核小体低分子RNA(snoRNA)の機能解析
  • 2021 - 2025 コリン作動系修飾物を介した血液脳関門強化と抗炎症作用による認知機能介入の可能性
  • 2021 - 2024 分裂終了細胞における新規な老化マーカーの探索とその機能の解析
  • 2014 - 2017 Discovery of Dwarfism Mouse Model by Deletion of PPAR gamma1 Specific Promoter.
  • 2013 - 2016 Proposed model that integrates cholesterol bidirectional flux in the small intestine
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Papers (42)：
  • Yasuhiro Takenaka, Yoshihiko Kakinuma, Masaaki Ikeda, Ikuo Inoue. Shared Mechanisms in Pparγ1sv and Pparγ2 Expression in 3T3-L1 Cells: Studies on Epigenetic and Positive Feedback Regulation of Pparγ during Adipogenesis. PPAR Research. 2024. 2024. 1. Article ID 5518933
  • Yuta Chiba, Yasuhiro Takenaka, Nobuyuki Haga. Identification and Characterization of the Gene Responsible for the O3 Mating Type Substance in Paramecium caudatum. Microorganisms. 2024. 12. 3. 588-588
  • Yasuhiro Takenaka, Masataka Hirasaki, Hidemasa Bono, Shigeo Nakamura, Yoshihiko Kakinuma. Transcriptome Analysis Reveals Enhancement of Cardiogenesis-Related Signaling Pathways by S-nitroso-N-pivaloyl-D-penicillamine (SNPiP): Implications for Improved Diastolic Function and Cardiac Performance. Journal of cardiovascular pharmacology. 2024
  • Yasuhiro Takenaka, Ikuo Inoue, Masataka Hirasaki, Masaaki Ikeda, Yoshihiko Kakinuma. Temporal inhibition of the electron transport chain attenuates stress-induced cellular senescence by prolonged disturbance of proteostasis in human fibroblasts. The FEBS journal. 2023. 290. 15. 3843-3857
  • Nobuyuki Haga, Toshinori Usui, Yasuhiro Takenaka, Yuta Chiba, Tomoaki Abe. Immaturin-Nuclease as a Model System for a Gene-Programmed Sexual Development and Rejuvenescence in Paramecium Life History. Microorganisms. 2022. 11. 1. 82-82
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MISC (18)：
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Patents (4)：
Lectures and oral presentations  (25)：
  • Analysis of senescence-associated protein aggregates in replicative senescent MRC-5 cells
    (第45回日本基礎老化学会 2022)
  • タンパク質恒常性機能の阻害により誘導される細胞老化とビタミンE及びラパマイシンの細胞老化抑制作用
    (第99回日本生理学会大会 2022)
  • プロテアソーム阻害剤等で誘導した細胞老化におけるミトコンドリア機能と生合成の解析
    (第43回日本基礎老化学会大会 2020)
  • Prolonged disturbances of proteostasis cause cellular senescence in normal human fibroblasts
    (2019)
  • Prolonged disturbances of proteostasis cause permanent cell cycle arrest and cellular senescence in normal human fibroblasts
    (17th RCGM Symposium of Academic Frontier 2019)
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Education (1)：
  • 1998 - 2002 University of Tsukuba
Professional career (1)：
  • 博士(農学) (筑波大学)
Work history (10)：
  • 2023/10 - 現在 Nippon Medical School Department of Bioregulatory Science
  • 2017/07 - 2023/09 Nippon Medical School Department of Physiology
  • 2016/04 - 2017/06 Japan patent office Patent and Design Examination Department (Physics, Optics, Social Infrastructure and Design)
  • 2011/04 - 2014/12 Saitama Medical University Department of Diabetes and Endocrinology Postdoc researcher
  • 2010/04 - 2011/03 National Institute of Advanced Industrial Science and Technology (AIST)
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Association Membership(s) (3)：
日本生化学会 ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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