2020 - 2023 Optimization of PDL cell-derived exosome by WNT/mechano signals and regulation of periodontal tissue regeneration
2020 - 2023 Molecular characterization and identification of novel therapeutic targets for the therapy-resistant apical periodontitis associated with inflammatory bowel disease.
2020 - 2023 Analysis of the molecular pathogenesis of aggressive periodontitis based on disease-derived induced pluripotent stem cells and PLAP-1
2020 - 2022 Retrospective quantitative analysis of juvenile stress using dentin matrix
2019 - 2022 Roles of long non-coding RNAs for periodontal diseases
2019 - 2022 Processing of surface modification for reinforcement of dentin by using active calcium phosphates.
2018 - 2021 Clarification of novel tissue destruction mechanism induced by mechanobiology breakdown
2018 - 2021 Development of new 3D bone regenerative medicine technology for horizontal bone defects using human ES cells
2016 - 2020 Establishment of Control Theory for Cementum Formation based on Wnt and Dentin Matrix Protein
2017 - 2020 Development of time controlled therapy for aged periodontal tissue.
2017 - 2020 Homeodynamics analysis of periodontal ligament tissue
2015 - 2019 Identification of genetic risk factors of aggressive periodontitis by genome wide approach
2015 - 2018 Enhancement of stem cell induced-periodontal tissue regeneration by utilizing hypoxia biology
2016 - 2018 Feasible research for novel periodontal regeneration therapeutics by CRISPR/Cas9
2015 - 2018 A basic study for the development of stem cell-cytokine therapy aimed at the enhancing periodontal tissue regeneration effect.
2015 - 2018 Effects of cathepsin A on the regeneration of periodontal ligament tissue
2014 - 2017 Development of novel therapeutics for the treatment of marfan syndrome using iPS technology
2014 - 2017 Establishment of ECM related Periodontal medicine
2014 - 2016 Feasible study for developing novel periodontal tissue regeneration therapies by chemical biological approaches
2013 - 2015 Analysis of SASP in chronic periodontal disease
2012 - 2015 On demand regulation of tissue regenerative environment at the recipient site of transplantation therapy and dental implant
2011 - 2015 Development of predictive periodontology based on molecular epidemiological study
2011 - 2014 Molecular analysis of inflammasome in periodontal tissue destruction and regeneration.
2012 - 2014 Molecular pathogenesis of aggressive periodontitis utilizing hereditary connective tissue disorder mouse model
2011 - 2014 A Challenge to the expansion of indications in periodontal tissue regeneration using FGF-2 by analyzing cross talk between signal molecules
2011 - 2013 Interaction between S1P and DAMPs in periodontal inflammation
2011 - 2012 Complexity single cell analysis designed to create a new periodontal regenerative medicine in silico
2011 - 2012 Establishment of screening system for novel therapeutics for periodontal disease by using low molecule compound
2010 - 2012 The effect of gradient FGF-2 on one-wall intrabony defect of periodontal tissue
2010 - 2011 Development of novel minimal intervention methods for periodontal tissue regeneration therapy
2009 - 2010 遺伝子改変マウス作製技術を応用した歯根膜再生モデル動物の開発
2009 - 2010 歯周組織幹細胞のエピジェネティクスとその制御の分子基盤
2008 - 2010 Molecular basis of predictable periodontal regeneration
2008 - 2010 Regulation of S1P in pathogenesis of periodontal disease
2008 - 2009 Periodontal system biology: analysis of molecular bases of periodontal disease associated genes.
2007 - 2008 バイオインテリジェント化幹細胞を用いた歯周組織移植療法の開発
2006 - 2008 The establishment of a new periodontal tissue regeneration therapyusing adipose-tissue derived stem cells
2006 - 2007 Regeneration of resorbed tooth roots by cementogenesis
2005 - 2007 Development of customized periodontal tissue regenerative therapy by transtiptome analysis of periodontal ligament
2005 - 2007 Molecular basis of periodontal ligament stem cells by bioinformatics
2003 - 2005 Molecular-biological analysis by DNA microarray for diagnosis of occlusal trauma
Kento Sasaki, Shigeki Suzuki, Rahmad Rifqi Fahreza, Eiji Nemoto, Satoru Yamada. Dynamic changes in chromatin accessibility during the differentiation of dental pulp stem cells reveal that induction of odontogenic gene expression is linked with specific enhancer construction. Journal of Dental Sciences. 2024. 19. 3. 1705-1713
Shigeki Suzuki, Kento Sasaki, Rahmad Rifqi Fahreza, Eiji Nemoto, Satoru Yamada. The histone deacetylase inhibitor MS-275 enhances the matrix mineralization of dental pulp stem cells by inducing fibronectin expression. Journal of Dental Sciences. 2024. 19. 3. 1680-1690
Yoshino Daidouji, Shigeki Suzuki, Xiuting Wang, Rahmad Rifqi Fahreza, Eiji Nemoto, Satoru Yamada. Periodontal inflammation potentially inhibits hepatic cytochrome P450 expression and disrupts the omega-3 epoxidation pathway in a murine model. Journal of Dental Sciences. 2024
Keiko Yamaki, Toru Tamahara, Jumpei Washio, Takuichi Sato, Ritsuko Shimizu, Satoru Yamada. Intracanal microbiome profiles of two apical periodontitis cases in one patient: A comparison with saliva and plaque profiles. Clinical and experimental dental research. 2024. 10. 2. e862
Jiajun Li, Yukihiko Sakisaka, Eiji Nemoto, Kentaro Maruyama, Shigeki Suzuki, Kaixin Xiong, Hiroyuki Tada, Taichi Tenkumo, Satoru Yamada. Cementocyte-derived extracellular vesicles regulate osteoclastogenesis and osteoblastogenesis. Journal of Dental Sciences. 2024
Japanese Association for Dental Research
, International Association for Dental Research
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
, THE JAPANESE SOCIETY OF INFLAMMATION AND REGENERATION
, THE JAPANESE SOCIETY OF CONSERVATIVE DENTISTRY
, JAPANESE SOCIETY OF PERIODONTOLOGY
