2011 - 2013 Investigation of cell function from the point of view of the regulatory mechanism for cellular localization of myocardin family members
2012 - 血管内皮細胞の間葉系細胞への形質転換が血管中膜平滑筋細胞に及ぼす影響に関する研究
2008 - 2010 Regulatory mechanism for the function of myocardin family members and its relation to cell phenotype
2008 - 2010 Study for the molecular basis of affective disorders caused by the dysregulated homeostasis of endocrine system
2003 - 2007 Establishment of a novel analysis system for three-dimentional structure of transmembrane receptors based on neuronal and vascular cell plasticity
2003 - 2004 Common mechanism in the regulation of s and hansaiption in muscle cell differentiation
2003 - 2004 Elucidation of the Molecular Mechanism of Atherosclerosis Induced by Unsaturted Lysophosphatidic Acid and Establishment of the Anti-athrosclerotic Therapy
2001 - 2002 Molecular mechanism of the signaling pathways that induce dedifferentiation of smooth muscle cells
2001 - 2002 平滑筋細胞の発生および形質転換における転写調節機構の解析
2001 - 2002 Study for the molecular mechanism of atherosclerosis
2001 - 2002 シナプス後肥厚部(PSD)特異蛋白質の検索と機能解析
1999 - 2001 SRFとホメオドメイン蛋白質による平滑筋特異的転写調節機構
2000 - 2000 シグナル伝達と転写制御から観た動脈硬化発症機構の解析
1998 - 1999 Signaling pathways regulating a phenotypic modulation of smooth muscle cells
1998 - 1999 動脈硬化誘導因子による脱分化機構の解析
1996 - 1997 Gene expressional mechanism in smooth muscle cells
1995 - 1996 Regulation of cytoskeleton by annexin VI
1995 - 1996 Developing a culture system of differentiated smooth muscle cells and phathological application
1995 - 1996 Molecular and cell biolobical analysis of the smooth muscle cell differentiation
1994 - 1995 Transcriptional regulation of caldesmon gene in smooth muscle cells
1995 - 1995 細胞骨格機能制御解析による神経可塑性の研究
1995 - 形質転換細胞における細胞骨格系蛋白質の機能と発現に関する研究
1993 - 1994 平滑筋及び非筋細胞におけるカルデスモンの転写調節
1994 - 1994 細胞骨格系による中枢シナプス機能発現の分子機作に関する研究
1993 - 1994 Interaction of annexins with membrane skeletal proteins in brain
1993 - 1994 Molecular Mechanism of the differentiation of smooth muscle cells
1994 - ガン細胞の細胞運動性における細胞骨格系蛋白質の機能に関する研
1993 - 1993 細胞骨格系による中枢シナプス機能発現の分子機作に関する研究
1993 - 1993 がん細胞に特有な細胞接着構造の分子構築の解明
1992 - 1993 Analyzes of dynamic molecular organization of the membrane skeleton
1992 - 1992 細胞骨格系による中枢シナプス機能発現に分子機作に関する研究
1991 - 1992 Interaction between ion channels and membrane skeleton
1991 - 1992 Analysis for the Expressional Change of Caldesmon Isoforms during Phenotyptic Modulation of Smooth Muscle Cells
Molecular mechanism of cell differentiation and dedifferentiation
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Papers (60)：
Ken’ichiro Hayashi, Masaaki Kobayashi, Kotaro Mori, Yoshiaki Nakagawa, Bunta Watanabe, Atsushige Ashimori, Fumiaki Higashijima, Takuya Yoshimoto, Junki Sunada, Tsuyoshi Morita, et al. The benzoylphenylurea derivative BPU17 acts as an inhibitor of prohibitin and exhibits antifibrotic activity. Experimental Cell Research. 2024. 442. 114221-114221
Tadahiko Ogata, Atsushige Ashimori, Fumiaki Higashijima, Ayano Sakuma, Waka Hamada, Junki Sunada, Ren Aoki, Masanori Mikuni, Kenichiro Hayashi, Takuya Yoshimoto, et al. HIF-1α-dependent regulation of angiogenic factor expression in Müller cells by mechanical stimulation. Experimental Eye Research. 2024. 110051-110051
Atsushige Ashimori, Fumiaki Higashijima, Tadahiko Ogata, Ayano Sakuma, Waka Hamada, Junki Sunada, Ren Aoki, Masanori Mikuni, Ken'ichiro Hayashi, Makiko Wakuta, et al. HIF-1α-dependent upregulation of angiogenic factors by mechanical stimulation in retinal pigment epithelial cells. Disease Models & Mechanisms. 2024
Kotaro Mori, Yoshiaki Nakagawa, Bunta Watanabe, Hiroshi Miyata, Tsuyoshi Morita, Ken'ichiro Hayashi. Novel ability of diflubenzuron as an inhibitor of mitochondrial function. Insect Biochemistry and Molecular Biology. 2024
Hayashi, K, Labios, R.J, Morita, T, Ashimori, A, Aoki, R, Mikuni, M, Kimura, K. Significance of the p38MAPK-CRP2 axis in myofibroblastic phenotypic transition. Cell Struct. Funct. 2023. 48. 2. 199-210
Expressional Regulation of Caldesmon Isoforms in Association with Phenotypic Modulation of Smooth Muscle Cells
Smooth Muscle Contraction ed. K. Kohama & K. Saida Japan Sci. Soc. Press. 1995
