Research theme for competitive and other funds (11)：
2024 - 2028 Role of immunosuppressive signal in the regulation of muscle homeostasis by exercise
2021 - 2025 オートファジー基質が制御するマイオカインの同定と応用
2020 - 2023 免疫抑制補助シグナルによる新たな筋萎縮抑制機構の解明
2018 - 2022 Role of autophagy adaptor in skeletal muscle
2016 - 2019 Role of exercise-induced myokine in peripheral arterial disease
2015 - 2018 Autophagy protein protects skeletal muscle atrophy
2014 - 2016 Molecular mechanisms in exercise training-induced atheroprotection
2013 - 2015 運動による骨格筋萎縮の抑制とその新規分子メカニズムの解明
2008 - 2008 Prevention of atherosclerosis by regular exercise
2007 - 2008 Establish methods of analysis to assess of muscle damage by circulating leukocytes.
2006 - 2007 Molecular mechanism of stress-induced atherogenesis
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Papers (38)：
Koichi Himori, Mami Yamada, Takahiro Onoki, Daisuke Matsumaru, Hozumi Motohashi, Mitsuharu Okutsu. Nrf2 deficiency in muscle attenuates experimental autoimmune myositis-induced muscle weakness. The Journal of Physiology. 2024
Mami Yamada, Eiji Warabi, Hisashi Oishi, Vitor A. Lira, Mitsuharu Okutsu. Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia. The Journal of Physiology. 2024. 602. 17. 4215-4235
Mami Yamada, Mitsuharu Okutsu. Interleukin-1β triggers muscle-derived extracellular superoxide dismutase expression and protects muscles from doxorubicin-induced atrophy. The Journal of Physiology. 2023. 601. 21. 4699-4721
Mami Yamada, Eiji Warabi, Hisashi Oishi, Vitor A. Lira, Mitsuharu Okutsu. Muscle p62 stimulates the expression of antioxidant proteins alleviating cancer cachexia. The FASEB Journal. 2023. 37. 9
Mitsuharu Okutsu, Mami Yamada, Ken Tokizawa, Shuri Marui, Katsuhiko Suzuki, Vitor A. Lira, Kei Nagashima. Regular exercise stimulates endothelium autophagy via IL-1 signaling in ApoE deficient mice. The FASEB Journal. 2021. 35. 7. e21698
2002 - Tohoku University Graduate School of Medicine Disability Science
Professional career (1)：
Ph.D. (Tohoku University School of Medicine)
Work history (10)：
2024 - 現在 Nagoya City University Graduate School of Science Professer
2020 - 2024 Nagoya City University Graduate School of Natural Sciences Associate Professor
2019 - 2020 Nagoya City University Graduate School of Natural Sciences
2014 - 2019 Nagoya City University Graduate School of Natural Sciences
2013 - 2014 Waseda University Faculty of Sport Sciences
2009 - 2013 Cardiovascular Research Center, Univesity of Virginia Research Associate
2008 - 2009 Duke-NUS Graduate Medical School Research Associate
2006 - 2008 Waseda University Consolidated Research Institute for Advanced Science and Medical Care
2004 - 2006 Waseda University Consolidated Research Institute for Advanced Science and Medical Care
2002 - 2004 Tohoku University New Industry Creation Hatchery Center
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Committee career (7)：
2023 - 現在 日本体力医学会 学術委員
2021 - 現在 Asian College of Exercise and Sports Science Assistant Secretary
2019 - 現在 Japanese Society of Physical Fitness and Health Negotiation committee
2017 - 現在 National Institute of Science and Technology Policy Professional researcher
2012 - 現在 Japanese Society of Physical Fitness and Health Councilor
2005 - 現在 Japanese Society of Exercise and Imunology Steering committee
2019 - 2021 Asian College of Exercise and Sports Science Preparatory committee
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Awards (12)：
2024 - 名古屋市立大学 理事長表彰
2020 - 学術論文(p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle, FASEB J, 2019)がFASEB Most Cited Articles Published Q3 2019に選出される
2020 - Nagoya City University President's Award
2020 - Nagoya City University High-impact manuscript award
2015 - Nagoya City University President's Award
2012 - University of Virginia Muscle Club Research Symposium Best Poster Award
2012 - Experimental Biology 2012 Postdoctoral Award
2011 - University of Virginia Department of Pharmacology Retreat Best Poster Award
2007 - Waseda University, ASMeW Outstanding Award
2007 - Japanease Society of Exercise and Immunology Moriguchi Award
2006 - Waseda University, ASMeW Outstanding Award
2005 - Japanease Society of Exercise and Immunology Moriguchi Award
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Association Membership(s) (7)：
日本筋学会
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, American Physiological Society
, Japanese Society of Exercise and Immunology
, International Society of Exercise and Immunology
, Japanese Society of Physical Fitness and Health
, 日本免疫学会
