Research field (3)：
Tumor diagnostics and therapeutics
, Other
, Human pathology
Research keywords (11)：
Urothelial cancer
, Lung Cancer
, in situ hybridization
, monoclonal antibody production
, intractable disease
, neoplasms
, Disease-associated autoantibody
, Disease-associated antigen
, proteomics
, immunohistochemistry
, Molecular Pathology
Research theme for competitive and other funds (70)：
2021 - 2024 Detection and application of bladder cancer specific proteins
2018 - 2021 Investigation of bladder cancer-specific protein and its establishment of diagnostic and treatment algorithm
2017 - 2020 Aquisition of novel useful predictive biomarkers of the efficacy of adjuvant chemotherapy in patients with non-small cell lung cancer and validate of those utilities.
2016 - 2019 Role of calcium sensing receptor in Kidney Type B Intercalated Cells
2018 - 2019 非小細胞性肺癌患者における術後補助化学療法の効果予測因子の検討
2015 - 2018 Analysis of newly detected serum protein and trial of establishment of diagnostic tool in patients with bladder cancer
2017 - 2018 非小細胞性肺癌患者における術後補助化学療法の効果予測因子の検討
2015 - 2018 自己抗体マーカー探索システムの開発
2014 - 2017 Acquisition strategy of tumor-specific markers using established micropapillary pattern pulmonary adenocarcinoma cell line
2016 - 2017 非小細胞性肺癌患者における術後補助化学療法の効果予測因子の検討
2015 - 2016 微小乳頭成分を有する肺腺癌の高悪性度生物学的特性に寄与する因子の解明
2013 - 2016 The search for effective intrapleural therapies and new biomarkers of mesothelioma.
2015 - 2016 樹立した微乳頭肺腺癌細胞株を用いた種々の腫瘍特異的マーカー獲得戦略
2012 - 2015 Detection of low affinity anti-tumor associated autoantibodies using evanescent-field fluorescence-assisted protein microarray system for application to the early diagnosis of lung cancer.
2012 - 2015 Detection of specific antibodies for bladder cancer
2012 - 2015 Proteomic analysis of lung adenocarcinoma with micropapillary component to achieve valuable biomarker
2012 - 2015 Factors related with carcinogenesis and invasion of ulcerative colitis-associated cancer
2011 - 2013 Exhaustive study for aquisition of eary diagnostic or the anti-cancer drug sensitivity markers for lung cancer
2011 - 2012 肺癌患者血清中の自己抗体の網羅的解析とその早期診断への応用
2011 - 2012 癌の早期診断マーカーとしての自己抗体の臨床検査への実用化に向けての検討
2009 - 2012 泌尿器系がんの診断用プローブ(オーファン診断薬・治療薬)の開発と臨床応用
2009 - 2012 がん検診に有用な腫瘍マーカーの開発
2010 - 2012 Establishment and application of the strategies for the discovery of biomarker proteins and peptides including species bound to albumin in serum/plasma
2003 - 2005 Improvement of ISH method for the detection of rare mRNAs in pathology archival tissues and establishment of its standard evaluation method
2003 - 2004 The roles of hASH1 gone in neuroendocrine differentiation of lung cancer and in the development of the lung
2000 - 2002 腫瘍および周辺組織におけるサイトカイン産生部位の同定
1998 - 2001 腫瘍および周辺組織におけるサイトカイン産生部位の同定
1997 - 1999 Distribution of cytokines in tumor tissues by in situ hybridization
1996 - 1998 腫瘍産生サイトカインのin situ hybridizationによる同定
1994 - 1996 腫瘍産生サイトカインのin situ hybridizationによる同定
1995 - 1996 Quantitative analysis of nm23 gene product in human cancers
1993 - 1994 Application of multi-purpose tissue fixation method (AMEX method) to the clinical laboratory
Kohei Mori, Kazumasa Matsumoto, Masaomi Ikeda, Dai Koguchi, Yuriko Shimizu, Hideyasu Tsumura, Daisuke Ishii, Shoutaro Tsuji, Yuichi Sato, Masatsugu Iwamura. Membranous Expression of Heart Development Protein with EGF-like Domain 1 Is Associated with a Good Prognosis in Patients with Bladder Cancer. Diagnostics. 2023. 13. 19. 3067-3067
Hiroki Katsumata, Kazumasa Matsumoto, Kengo Yanagita, Yuriko Shimizu, Shuhei Hirano, Kazuki Kitajima, Dai Koguchi, Masaomi Ikeda, Yuichi Sato, Masatsugu Iwamura. Expression of S100A16 Is Associated with Biological Aggressiveness and Poor Prognosis in Patients with Bladder Cancer Who Underwent Radical Cystectomy. International Journal of Molecular Sciences. 2023. 24. 19. 14536-14536
Dai Koguchi, Kazumasa Matsumoto, Masaomi Ikeda, Yuriko Shimizu, Marie Nakamura, Yutaka Shiono, Hiroki Katsumata, Yuichi Sato, Masatsugu Iwamura. Gemcitabine-Paclitaxel Chemotherapy for Patients with Advanced Urothelial Cancer Refractory to Cisplatin-Based Chemotherapy: Predictive Role of PGK1 for Treatment Response to Cytotoxic Chemotherapy. International Journal of Molecular Sciences. 2022. 23. 20. 12119-12119
Shuhei Hirano, Kazumasa Matsumoto, Kei Tanaka, Noriyuki Amano, Dai Koguchi, Masaomi Ikeda, Yuriko Shimizu, Benio Tsuchiya, Ryo Nagashio, Yuichi Sato, et al. DJ-1 Expression Might Serve as a Biologic Marker in Patients with Bladder Cancer. Cancers. 2022. 14. 10. 2535-2535
Kohei Mori, Kazumasa Matsumoto, Noriyuki Amano, Dai Koguchi, Soichiro Shimura, Masahiro Hagiwara, Yuriko Shimizu, Masaomi Ikeda, Yuichi Sato, Masatsugu Iwamura. Expression of Membranous CD155 Is Associated with Aggressive Phenotypes and a Poor Prognosis in Patients with Bladder Cancer. Cancers. 2022. 14. 6. 1576-1576
Membranous expression of S100A16 in bladder cancer.
(The 65th Annual Meeting of the Japan Society of Histochemistry and Cytochemistry 2024)
O-204 Membranous expression of non-sialylated HEG1 in bladder cancer
(2023)
New Method to detect Erythropoietin
(BioJapan 2023 2023)
P-68 DJ-1 expression might serve as a biologic marker in patients with bladder cancer
(The 68th Annual Meeting of the Japanese Society of Pathology 2022)
