Rchr
J-GLOBAL ID:200901042708552588
Update date: Nov. 02, 2024
Iizasa Hisashi
イイザサ ヒサシ | Iizasa Hisashi
Affiliation and department:
Job title:
Professor
Other affiliations (1):
Homepage URL (1):
https://yoshiyama-lab.org/
Research field (4):
Infectious disease
, Bacteriology
, Virology
, Laboratory animal science
Research theme for competitive and other funds (20):
- 2022 - 2025 Study of APOBEC3 family involved in early tumorigenesis of EB virus-infected epithelial cells.
- 2022 - 2025 EBウイルス再活性化を認めるLong COVIDに対する予防・治療法の開発
- 2020 - 2023 Safetyness and efficacy of mucosal route of immunotherapy with transgenic rice seads containing whole T cell epitopes of Cryj1 and Cryj2 for patients with japanese cedar pollinosis
- 2019 - 2022 上咽頭癌を引き起こす高発癌性EBウイルス株の同定と治療薬の開発.
- 2018 - 2021 ETS transcription factors induced by EBV in gastric epithelial cells regulate viral miRNA expression
- 2016 - 2019 Research on relations between regional distribution of nasopharyngeal cancer and genomic polymorphism of Epstein-Barr virus for vaccine development
- 2015 - 2018 Development of sublingual immunotherapy with Transgenic rice seeds in patients with cedar pollinosisi
- 2014 - 2018 Enhancement of invasiveness of cancer cells by hypoxia-induced expression of HOX genes
- 2017 - 2018 非コードRNA NEAT1によるEpstein-Barrウイルス潜伏感染制御機構の解明.
- 2014 - 2017 Effect of H. pylori coinfection on genesis of EB virus associated gastric cancer
- 2013 - 2014 RNA編集酵素ADAR1による造血幹細胞増殖·分化制御機構の解明
- 2011 - 2013 The effect of EB virus infection in nasopharyngeal carsinoma cancer stem cell
- 2011 - 2013 Identification of HOX gene which suppresses hepatic metastasis of colon cancer
- 2010 - 2011 Development of new regeneration therapy by targeting of miRNA
- 2005 - 2006 血液胎盤関門における妊娠時期依存的な胎児解毒機構の解明.
- 2004 - 2005 ROLE OF ENDOTHELIAL CELL, PERICYTE, AND ASTROCYTE ON BASEMENT MEMBRANE METABOLISM IN BLOOD-TISSUE BARRIER
- 2002 - 2003 条件的不死化細胞株を用いた血液-胎盤関門の胎児解毒機構と薬物間相互作用の解析
- 2001 - 2003 Investigation of pericyte unique gene related to the formation of tight junction in blood brain barrier
- 2000 - 2001 遺伝子欠損マウス病態モデルを用いた複合的IL-1ra機能解析
- 1998 - 1999 Effect of chemokine gene transfection on acquistion of whole body tumor immunity
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Papers (101):
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Yuxin Liu, Aung Phyo Wai, Tumurgan Zolzaya, Yuichi Iida, Shunpei Okada, Hisashi Iizasa, Hironori Yoshiyama. Exploring the anti-EBV potential of suberoylanilide hydroxamic acid: induction of apoptosis in infected cells through suppressing BART gene expression and inducing lytic infection. Virology. 2024. 110161-110161
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Afifah Fatimah Azzahra Ahmad Wadi, Daichi Onomura, Hirokazu Funamori, Mst Mahmuda Khatun, Shunpei Okada, Hisashi Iizasa, Hironori Yoshiyama. Effects of Strain Differences, Humidity Changes, and Saliva Contamination on the Inactivation of SARS-CoV-2 by Ion Irradiation. Viruses. 2024. 16. 4. 520-520
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Chukkris Heawchaiyaphum, Hironori Yoshiyama, Hisashi Iizasa, Ati Burassakarn, Zolzaya Tumurgan, Tipaya Ekalaksananan, Chamsai Pientong. Epstein-Barr vrus promotes oral squamous cell carcinoma stemness through the Warburg effect. International Journal of Molecular Sciences. 2023. 23. 24. 14072-14072
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Amrizal Muchtar, Ramdhani M. Natsir, Minarty M. Natsir, Andi Sitti Fahirah Arsal, Hisashi Iizasa, Hironori Yoshiyama. In silico Analysis Predicts that Mir-6770-5p Can Target the X Gene of All Hepatitis B Virus Genotypes. International Journal Bioautomation. 2023. 27. 3. 161-176
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Sintayehu Fekadu, Hizkel Engiso, Sisay Seyfe, Hisashi Iizasa, Ashebir Godebo, Serawit Deyno, Hironori Yoshiyama. Effectiveness of eradication therapy for Helicobacter pylori infection in Africa: a systematic review and meta-analysis. BMC Gastroenterology. 2023. 23. 1
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MISC (51):
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飯笹 久, 小野村 大地, 劉 雨新, ファティマ・アフィファ, 岡田 俊平, 吉山 裕規. miR-3145-3pはウイルス増殖時の小胞体ストレスにより誘導されるHBV抑制因子である(miR-3145-3p is an HBV suppressor induced by endoplasmic reticulum stress during virus replication). 日本癌学会総会記事. 2023. 82回. 492-492
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劉 雨新, 飯笹 久, アウンヒョウ・ワイ, ファティマ・アフィファ, カトゥン・マストマフムダ, チンマー・モウ, 岡田 俊平, 吉山 裕規. チロシンキナーゼ阻害剤ダサチニブはEBウイルス感染胃上皮細胞特異的にアポトーシスを導く(Tyrosine kinase inhibitor dasatinib specifically induces apoptosis in EB virus-infected gastric epithelial cells). 日本癌学会総会記事. 2023. 82回. 510-510
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岡田 俊平, 飯笹 久, Azzahra Afifah Fatimah, Khatun Mosammat Mahmuda, Thin Myat Moe, 吉山 裕規. 新型コロナウイルス感染症の現況. 島根医学. 2023. 43. 1. 1-10
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岡田俊平, KHATUN Mosammat Mahmuda, 飯笹久, 宇田川愛美, 上村尚人, 吉山裕規. Study on the SARS-CoV-2 discontinuous transcription mechanism important for distinct-size subgenomic RNA synthesis. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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ワイ・アウンヒョウ, 飯笹 久, モウ・シンミャット, カトゥン・マストマスムダ, 小野村 大地, 岡田 俊平, 吉山 裕規. ブレオマイシン類似体であるゼオシンは、EBV陽性胃がんの細胞死を優先的に導く。(Zeocin, a bleomycin analog, induces preferential EBV-positive gastric cancer cell death.). 日本癌学会総会記事. 2022. 81回. E-1014
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Patents (12):
Books (33):
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核酸医薬・mRNA医薬の製造分析の基礎と基盤技術開発
シーエムシー・リサーチ 2023 ISBN:9784910581347
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EB ウイルス関連胃癌胃.特集:内視鏡検診時代の胃診断学-胃粘膜を観る!胃癌を診る!
消化器内視鏡 2017
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DNA/RNA編集研究の新たな眺望
日本生化学会 2017
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医学のあゆみ第5土曜特集 RNA医学•医療-あらたな診断•治療を拓く
医歯薬出版 2011
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ファルマシア(細胞分化と排出:ABCトランスポーターの意外な側面.)
日本薬学会 2002
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Lectures and oral presentations (220):
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Helicobacter pyloriの胃上皮細胞への接着はウイルス受容体の発現を誘導し、EBV感染を促進する.
(第68回日本ウイルス学会学術集会. 2021)
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Helicobacter pyloriの胃上皮細胞への接着は低親和性ウイルス受容体の発現を誘導し、EBV感染を促進する.
(第74回日本細菌学会中国・四国支部総会. 2021)
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Helicobacter pylori adhesion to gastric epithelial cells induces viral receptor expression and promotes EBV infection.
(2021)
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Identification of human miRNA that directly target hepatitis B virus genomic RNA.
(2021)
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Helicobacter pyloriの胃上皮細胞への接着は、EphA2およびNMHC-IIAの発現を誘導し、EBV感染を促進する.
(第34回ヘルペスウイルス研究会. 2021)
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Education (4):
- 2004 - 2004 Kitasato University Graduate School of Pharmaceutical Sciences
- 1994 - 1998 Kanazawa University
- 1992 - 1994 Kitasato University
- 1988 - 1992 Kitasato University
Professional career (2):
- 博士(薬学) (北里大学)
- 修士(学術) (北里大学)
Work history (9):
- 2024/11 - Shimane University Graduate School of Medical Sciences Professor
- 2024/11 - Shimane University Faculty of Medicine Professor
- 2018/04 - 2024/10 Shimane University Graduate School of Medical Sciences Associate Professor
- 2016/06 - 2024/10 Shimane University Faculty of Medicine Associate Professor
- 2014/04 - 2016/05 Shimane University Faculty of Medicine Assistant Professor
- 2009/07 - 2014/03 Hokkaido University Institute for Genetic Medicine Assistant Professor
- 2005/10 - 2009/06 The Wistar Institute Gene Expression and Regulation Postdoctoral Fellow
- 2005/04 - 2005/09 Mount Sinai School of Medicine Immunology Center Postdoctoral Fellow
- 1998/04 - 2005/03 Kyortsu University of Pharmacy Faculty of Pharmacy Research Instructor
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Awards (1):
- 2003 - The APSTJ Global Education Seminar Presentation Award 2003
Association Membership(s) (5):
THE JAPANESE SOCIETY FOR VIROLOGY
, JAPANESE SOCIETY FOR BACTERIOLOGY
, 日本癌学会
, 日本RNA学会
, 日本分子生物学会
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