Rchr
J-GLOBAL ID：200901042929480506   Update date: Oct. 09, 2024

Yasutomi Yasuhiro

ヤストミ ヤスヒロ | Yasutomi Yasuhiro
Affiliation and department：
National Institutes of Biomedical Innovation,Health and Nutrition Tsukuba Primate Research Center

About National Institutes of Biomedical Innovation,Health and Nutrition Tsukuba Primate Research Center


Job title： Director
Other affiliations (1)：
Homepage URL  (1)： http://www.yasutomi-group.jp
Research field  (2)： Immunology ,  Virology
Research keywords  (2)： 免疫学 ,  Immunology
Research theme for competitive and other funds  (34)：
  • 2021 - 2023 Study of pneumonia in SARS-CoV-2 reinfection by primate COVID-19 model
  • 2017 - 2020 Study of tuberculosis and development of vaccine in latent infected cynomolgus monkeys.
  • 2017 - 2020 Control of senescence-associated T cell-induction
  • 2016 - 2017 Establishment of a non-human primate model using cynomolgus monkeys for evaluating anti-HTLV-I mother to child infection drugs.
  • 2015 - 2017 Edible vaccine production using plastid transformation in plants.
Show all
Papers (148)：
  • Chieko Yokota, Kosuke Fujimoto, Natsuko Yamakawa, Masamitsu Kono, Daichi Miyaoka, Masaki Shimohigoshi, Miho Uematsu, Miki Watanabe, Yukari Kamei, Akira Sugimoto, et al. Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci. Inflammation and regeneration. 2023. 43. 1. 55-55
  • Emiko Urano, Yumi Itoh, Tatsuya Suzuki, Takanori Sasaki, Jun-Ichi Kishikawa, Kanako Akamatsu, Yusuke Higuchi, Yusuke Sakai, Tomotaka Okamura, Shuya Mitoma, et al. An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models. Science translational medicine. 2023. 15. 711. eadi2623
  • Yoshiko Munesue, Naohide Ageyama, Nobuyuki Kimura, Ichiro Takahashi, Shunya Nakayama, Sachi Okabayashi, Yuko Katakai, Hiroshi Koie, Ken ichi Yagami, Kazuhiro Ishii, et al. Cynomolgus macaque model of neuronal ceroid lipofuscinosis type 2 disease. Experimental Neurology. 2023. 363
  • Shokichi Takahama, Kazuya Ishige, Takuto Nogimori, Yasuhiro Yasutomi, Victor Appay, Takuya Yamamoto. Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates. Molecular therapy. Methods & clinical development. 2023. 28. 99-115
  • Shihoko Kimura-Ohba, Masamitsu N. Asaka, Daichi Utsumi, Yoshitsugu Takabatake, Atsushi Takahashi, Yasuhiro Yasutomi, Yoshitaka Isaka, Tomonori Kimura. d-Alanine as a biomarker and a therapeutic option for severe influenza virus infection and COVID-19. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2023. 1869. 1. 166584-166584
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MISC (203)：
  • 内田慎介, 鯉江洋, 中山駿矢, 中山駿矢, 伊藤(藤城)康世, 山海直, 保富康宏, 揚山直英. カニクイザルにおける体成分分析装置を用いた新規評価法の樹立. 日本実験動物学会総会講演要旨集(Web). 2024. 71st
  • 日比野功哉, 鯉江洋, 酒井克也, 長船健二, 安田勝太郎, 中山俊也, 中山俊也, 山海直, 保富康宏, 揚山直英. Fibroscanを用いたカニクイザル肝硬変モデルの病態評価. 日本実験動物学会総会講演要旨集(Web). 2024. 71st
  • 妻鹿佑紀, 鯉江洋, 酒井克也, 中山駿矢, 中山駿矢, 山海直, 保富康宏, 揚山直英. フィブロスキャンを用いたカニクイザル肝線維化における基準値の樹立. 日本実験動物学会総会講演要旨集(Web). 2023. 70th
  • 日比野功哉, 鯉江洋, 酒井克也, 中山駿矢, 中山駿矢, 妻鹿佑紀, 成田貴則, 山海直, 保富康宏, 揚山直英. カニクイザル肝線維症モデルを用いたフィブロスキャンの有用性検討. 日本獣医学会学術集会講演要旨集. 2023. 166th
  • 妻鹿佑紀, 鯉江洋, 酒井克也, 中山駿矢, 中山駿矢, 日比野功哉, 岡林堅, 山海直, 保富康宏, 揚山直英. カニクイザルを用いたフィブロスキャンによる肝線維化評価指標の樹立. 日本獣医学会学術集会講演要旨集. 2023. 166th
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Patents (3)：
  • α抗原またはα抗原遺伝子の新規医薬用途
  • DNAワクチンに対するアジュバント剤
  • BCGによるアトピー性疾患の治療法
Books (9)：
  • Structure-based study of viral replication.
    World Scientific . 2009
  • The SIVmac cytotoxic T lymphocyte response in acutely infected rhesus monkey (共著)
    Simian Immunodeficiency virus 1994
  • Combined modality immunization for elicitation of SIV mac gag-specific CTL. (共著)
    Vaccine 94 1994
  • The SIVmac cytotoxic T lymphocyte response in acutely infected rhesus monkey (共著)
    Simian Immunodeficiency virus 1994
  • Combined modality immunization for elicitation of SIV mac gag-specific CTL. (共著)
    Vaccine 94 1994
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Education (4)：
  • - 1990 Rakuno Gakuen University
  • - 1990 Rakuno Gakuen University Graduate School, Division of Veterinary Medicine and Animal Scinces
  • - 1986 Rakuno Gakuen University Faculty of Dairy Science
  • - 1986 Rakuno Gakuen University Faculty of Dairy Science
Professional career (1)：
  • PhD, DVM
Work history (4)：
  • 2007 - - 医薬基盤研究所霊長類医科学研究センター長、 三重大学大学院医学系研究科 教授
  • 1992 - 1996 Harvard University
  • 1996 - - 三重大学医学部助教授
  • 1990 - 1991 Harvard University
Awards (1)：
  • 2006 - 「多ケ谷勇記念ワクチン研究」イスクラ奨励賞
Association Membership(s) (8)：
米国免疫学会 ,  日本ワクチン学会 ,  日本ウィルス学会 ,  日本エイズ学会 ,  日本寄生虫学会 ,  日本免疫学会 ,  日本癌学会 ,  日本獣医学会
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