Rchr
J-GLOBAL ID:200901043036396333   Update date: Oct. 10, 2018

KITABAYASHI Issay

キタバヤシ イッセイ | KITABAYASHI Issay
Affiliation and department:
Job title: Deputy Director/Chief
Homepage URL  (1): http://www.ncc.go.jp/jp/nccri/divisions/12moon/12moon.html
Research field  (3): Tumor biology ,  Molecular biology ,  Hematology
Research keywords  (4): leukemia ,  cell differentiation ,  chromosome translocation ,  Histone acetylation
Research theme for competitive and other funds  (8):
  • 2007 - 2009 Study for regulatory mechanism of normal and leukemic stem cells through transcription factors
  • 2005 - 2009 Functional study of leukemia-associated factor AML1
  • 2003 - 2005 AML1 complex as a molecular target for leukemia therapy
  • 2000 - 2002 STUDY OF HISTONE ACETYLATION REGULATION IN LEUKEMOGENESIS
  • 1999 - 2000 Histone acetylation and human leukemia
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Papers (41):
  • Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, Kitabayashi I, Tashiro F, Namiki H, Kondo T, Semba K, Aburatani H, Taya Y, Nakagama H, Ohki R. IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis. Scientific reports. 2016. 6. 19174
  • Nakagawa M, Kitabayashi I. Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies. Cancer science. 2018. 109. 8. 2342-2348
  • Tabu K, Muramatsu N, Mangani C, Wu M, Zhang R, Kimura T, Terashima K, Bizen N, Kimura R, Wang W, Murota Y, Kokubu Y, Nobuhisa I, Kagawa T, Kitabayashi I, Bradley M, Taga T. A Synthetic Polymer Scaffold Reveals the Self-Maintenance Strategies of Rat Glioma Stem Cells by Organization of the Advantageous Niche. Stem cells (Dayton, Ohio). 2016. 34. 5. 1151-1162
  • Shima H, Takamatsu-Ichihara E, Shino M, Yamagata K, Katsumoto T, Aikawa Y, Fujita S, Koseki H, Kitabayashi I. Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells. Blood. 2018. 131. 16. 1833-1845
  • Ikawa Y, Nishimura R, Maeba H, Fujiki T, Kuroda R, Noguchi K, Fukuda M, Mase S, Araki R, Mitani Y, Sato T, Terui K, Ito E, Kitabayashi I, Yachie A. Deep spontaneous molecular remission in a patient with congenital acute myeloid leukemia expressing a novel MOZ-p300 fusion transcript. Leukemia & lymphoma. 2018. 1-3
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MISC (30):
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Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (2):
  • 2002/10 - 2010/03 National Cancer Center Research Institute Chief
  • 2010/04 - 現在 National Cancer Center Research Institute Vice Director/Chief
Awards (1):
  • Japanese Cancer Association JCA-Mauvernay Award Molecular study of acute myeloid leukemia and its application for therapy
Association Membership(s) (4):
The Japanese Cancer Association ,  The Molecular Biology Society of Japan ,  The American Society of Hematology ,  The Japanese Society of Hematology
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