Tohoku University Graduate School of Medicine United Centers for Advanced Research and Translational Medicine Center for Cancer Research Cell proliferation
About Tohoku University Graduate School of Medicine United Centers for Advanced Research and Translational Medicine Center for Cancer Research Cell proliferation
2003 - 2004 Analysis of the PKC-δ Signaling Pathway by Proteomics with Embryonic and Genetic Engeneering
2003 - 2004 プロテアソームへのユビキチン化基質のターゲッテング機構の解析
2003 - 2004 Study of molecular mechanisms of CD4 silencing and role s of Runx proteins during lymphocyte development
2003 - 2003 サイクリンEのユビキチンリガーゼCdc4が細胞周期進行に果たす役割
2002 - 2003 リボザイムを用いた組織特異的ノックアウトマウス作製法の開発
2002 - 2003 マウスGemininの発生工学的手法を用いた機能解析
2002 - 2002 プロテアソームへのユビキチン化基質のターゲッテング機構の解析
2002 - 2002 2種類のサイクリンE分解機構の細胞周期進行における役割
2001 - 2002 Establishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteinsEstablishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteins
2001 - 2002 New cancer therapy by degradation of specific proteins
2001 - 2002 New clearance system of abnormal protein in Polyglutammine disease
2001 - 2001 中心体過剰複製と染色体倍数性異常の発がんにおける役割の研究
2000 - 2001 Functional analysis of ubiquitin ligase by knock-out mise
2000 - 2000 Cyclin E過剰蓄積とp27の欠損を伴うマウスを用いた発がん機構の研究
1999 - 2000 Identification of the factors mediating ubiquitination of inclusion body in neurodegenerative diseases
1997 - 1998 Analysis of sinnalling pathway of apoptosis degradation using PKCδ gene-targeting mice
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Papers (279):
Satoru Naito, Taiki Kajiwara, Hideaki Karasawa, Tomoyuki Ono, Tatsushi Saito, Ryo Funayama, Keiko Nakayama, Shinobu Ohnuma, Michiaki Unno. Calreticulin exposure induced by anticancer drugs is associated with the p53 signaling pathway in colorectal cancer cells. Biochemical and Biophysical Research Communications. 2024. 733. 150665-150665
Kyoko Ochiai, Hiroki Shima, Toru Tamahara, Nao Sugie, Ryo Funayama, Keiko Nakayama, Tomohiro Kurosaki, Kazuhiko Igarashi. Accelerated plasma-cell differentiation in Bach2-deficient mouse B cells is caused by altered IRF4 functions. The EMBO journal. 2024
Liang Liu, Mitsuyo Matsumoto, Miki Watanabe-Matsui, Tadashi Nakagawa, Yuko Nagasawa, Jingyao Pang, Bert K K Callens, Akihiko Muto, Kyoko Ochiai, Hirotaka Takekawa, et al. TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. International journal of molecular sciences. 2024. 25. 8
Yukihiro Sato, Minoru Kobayashi, Masahiro Ohira, Ryo Funayama, Masamitsu Maekawa, Hideaki Karasawa, Ryosuke Kashiwagi, Yayoi Aoyama, Nariyasu Mano, Shinobu Ohnuma, et al. Downregulation of ABCC3 activates MAPK signaling through accumulation of deoxycholic acid in colorectal cancer cells. Cancer science. 2024
Rumiko Izumi, Kensuke Ikeda, Tetsuya Niihori, Naoki Suzuki, Matsuyuki Shirota, Ryo Funayama, Keiko Nakayama, Hitoshi Warita, Maki Tateyama, Yoko Aoki, et al. Nuclear pore pathology underlying multisystem proteinopathy type 3-related inclusion body myopathy. Annals of clinical and translational neurology. 2023
高橋勝彦, 難波美早, 柿崎良輔, 及川里奈, 天野均, 浦野友彦, 中山啓子, 中山敬一, 東伸昭. 1,25(OH)2VD3-induced adipogenesis and osteoclastgenesis in osteblasts depend on p57Kip2. 日本薬学会年会要旨集(Web). 2024. 144th
柿崎良輔, 及川里奈, 高橋優太, 天野均, 浦野友彦, 中山啓子, 中山敬一, 高橋勝彦, 東伸昭. Vitamin D3-induced adipogenesis in osteoblasts depends on p57Kip2. 日本薬学会年会要旨集(Web). 2023. 143rd
中野智太, 森谷邦彦, 菊池敦生, 新妻秀剛, 笹原洋二, 舟山亮, 中山啓子, 城田松之, 新堀哲也, 青木洋子, et al. Molecular pathogenesis in two cases of IMAGE-I syndrome with novel POLE mutations. 日本免疫不全・自己炎症学会雑誌(Web). 2023. 2. 2
An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3
(31ST INTERNATIONAL SYMPOSIUM ON ALS/MND 2020)