Hashimoto Hisashi

ハシモトヒサシ | Hashimoto Hisashi

Affiliation and department：
Job title： Senior Researcher

Research field (3)： Other , Other , Genetics

Research keywords (3)：細胞進化 , 細胞多様性・新奇細胞種 , 色素細胞

Research theme for competitive and other funds (19)：

2024 - 2027 色素細胞の創出と喪失の進化発生メカニズム
2020 - 2023 Evolutionary genetic basis of developmental regulation of a novel cell type
2018 - 2019 メダカをモデルとした色素斑形成の遺伝基盤に関する研究〜色素細胞におけるプロテインキナーゼAの活性制御メカニズム
2014 - 2018 Analysis of molecular mechanisms controlling fate choice of pigment cells
2014 - 2017 Molecular basis fo protein-crosslinking reaction by transglutaminase focusing on aberrant regulation

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Papers (74)：

Motohiro Miyadai, Hiroyuki Takada, Akiko Shiraishi, Tetsuaki Kimura, Ikuko Watakabe, Hikaru Kobayashi, Yusuke Nagao, Kiyoshi Naruse, Shin-Ichi Higashijima, Takashi Shimizu, et al. A gene regulatory network combining Pax3/7, Sox10 and Mitf generates diverse pigment cell types in medaka and zebrafish. Development (Cambridge, England). 2023. 150. 19
Makoto Goda, Asuka Miyagi, Takuya Kitamoto, Minako Kondo, Hisashi Hashimoto. Uric acid is a major chemical constituent for the whitish coloration in the medaka leucophores. Pigment cell & melanoma research. 2023. 36. 5. 416-422
Takumi Wagatsuma, Eisuke Suzuki, Miku Shiotsu, Akiko Sogo, Yukina Nishito, Hideya Ando, Hisashi Hashimoto, Michael J Petris, Masato Kinoshita, Taiho Kambe. Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins. Communications biology. 2023. 6. 1. 403-403
Yuri Tsunogai, Motohiro Miyadai, Yusuke Nagao, Keisuke Sugiwaka, Robert N Kelsh, Masahiko Hibi, Hisashi Hashimoto. Contribution of sox9b to pigment cell formation in medaka fish. Development, growth & differentiation. 2021. 63. 9. 516-522
Hamied Atyaf, Alnedawy Qusay, Correia Ana, Hacker Christian, Ramsdale Mark, Hashimoto Hisashi, Kudoh Tetsuhiro. Identification and Characterization of Highly Fluorescent Pigment Cells in Embryos of the Arabian Killifish (Aphanius Dispar). ISCIENCE. 2020. 23. 11

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MISC (4)：

Patents (3)：

Books (13)：

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Lectures and oral presentations (103)：

Hypothesis for variegated body pigmentation based on aberrant regulation of PKA activity.
Biochemical phenotypes of the knockout medaka for the α2,6-sialyltransefrases I and II genes
CMP-Sia synthetase and sialylation are essential for embryogenesis in medaka
Pax3b and Pax7a have sequential function to regulate fate choice of pigment cells in medaka
(第53回日本発生生物学会大会 2019)
Roles of Sox9b in medaka pigment cell development
(第53回日本発生生物学会大会)

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Education (3)：

Professional career (1)：

Work history (8)：

2024/04 - 現在リージョナルフィッシュ株式会社研究開発部
2023/04 - 2024/03 Nagoya University Graduate School of Science
2019/04 - 2023/03 Nagoya University Graduate School of Science, Division of Biological Science
2002/11 - 2019/03 Nagoya University Bioscience and Biotechnology Center Development and Applied Division Assistant Professor
2012/04 - 2012/10 University of Bath Department of Biology and Biochemistry Visiting researcher

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Association Membership(s) (3)：

日本動物学会 , 日本分子生物学会 , 日本発生生物学会

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