Rchr
J-GLOBAL ID：200901043397093190   Update date: Apr. 30, 2024

Osafune Kenji

オサフネ ケンジ | Osafune Kenji
Affiliation and department：
Kyoto University

About Kyoto University


Homepage URL  (2)： https://www.cira.kyoto-u.ac.jp/j/research/osafune_summary.html ,  http://www.osafune.icems.kyoto-u.ac.jp/
Research field  (1)： Nephrology
Research keywords  (6)： 再生 ,  腎臓 ,  iPS細胞 ,  Regeneration ,  Kidney ,  iPS cell
Research theme for competitive and other funds  (2)：
  • 2008 - 2012 ヒトiPS細胞を用いた腎臓再生医療の開発
  • 2008 - 2012 Development of regenerative medicine for kidney disease with iPS cell
Papers (94)：
  • Hiraku Tsujimoto, Azusa Hoshina, Shin-Ichi Mae, Toshikazu Araoka, Wang Changting, Yoshihiro Ijiri, May Nakajima-Koyama, Satoko Sakurai, Kazusa Okita, Ken Mizuta, et al. Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells. Cell Reports. 2024. 43. 2. 113602
  • Shin-Ichi Mae, Fumihiko Hattanda, Hiroyoshi Morita, Aya Nozaki, Naoko Katagiri, Hanako Ogawa, Kaori Teranaka, Yu Nishimura, Aoi Kudoh, Sanae Yamanaka, et al. Human iPSC-derived renal collecting duct organoid model cystogenesis in ADPKD. Cell Reports. 2023. 42. 12. 113431
  • Hasan Al Reza, Zishaan Farooqui, Abid Al Reza, Callen Conroy, Kentaro Iwasawa, Yasuhiro Ogura, Keisuke Okita, Kenji Osafune, Takanori Takebe. Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids. Stem Cell Reports. 2023. 18. 11. 2071-2083
  • Ryuichiro Hirayama, Kosuke Toyohara, Kei Watanabe, Takeya Otsuki, Toshikazu Araoka, Shin-Ichi Mae, Tomoko Horinouchi, Tomohiko Yamamura, Keisuke Okita, Akitsu Hotta, et al. iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome. Communications Biology. 2023. 6. 1. 854
  • Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, et al. Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition. Drug Metabolism and Disposition. 2023. 51. 9. 1177-1187
ｍore...
MISC (226)：
  • 前伸一, 長船健二. 腎臓オルガノイドを用いた創薬研究の進歩と展望. 日腎会誌2023. 2023. 65. 8. 923-929
  • 清水達也, 山縣邦弘, 長船健二. 腎オルガノイドを用いた多発性嚢胞腎モデル解析. 腎臓内科 (科学評論社). 2023. 17. 6. 642-649
  • 長船健二. 腎オルガノイドを用いた研究展望. 腎臓内科 (科学評論社). 2023. 17. 6. 627-633
  • 河野 有香, 小林 恭, 長船健二. 「腎臓オルガノイド」. Medical Science Digest (ニューサイエンス社). 2023. 49. 5
  • 大槻 健弥, 長船 健二. iPS細胞. 「腎と透析」(東京医学社). 2023. 94. 3. 359-362
ｍore...
Books (1)：
  • もっとよくわかる!幹細胞と再生医療
    羊土社 2014
Lectures and oral presentations  (428)：
  • 「iPS細胞による1型糖尿病根治」
    (日本IDDMネットワーク サイエンスフォーラム in 大阪)
  • 臓器再生のフロンティア「iPS 細胞を用いた腎、膵、肝疾患に対する再生医療と新規治療薬の開発」
    (第 96 回日本内分泌学会学術総会特別シンポジウム3 2023)
  • “Liver Regeneration Using iPSC in Liver Cirrhosis”
    (The Liver Week 2023 2023)
  • iPSC technology-based regenerative medicine”
    (2023)
  • “iPSC-based regenerative therapies for kidney diseases and diabetes”
    (A*CGT Symposium 2023 2023)
ｍore...
Work history (10)：
  • 2022/04 - 現在 Center for iPS Cell Research and Application, Kyoto University Department of Cell Growth and Differentiation Department Head
  • 2014/10 - 現在 Center for iPS Cell Research and Application, Kyoto University Professor
  • 2010/04 - 2014/09 Center for iPS Cell Research and Application, Kyoto University Associate Professor
  • 2008/06 - 2010/03 Japan Science and Technology Agency PRESTO Research Fellow
  • 2008/06 - 2010/03 Center for iPS Cell Research and Application, Institute for Integrated Cell-Material Sciences, Kyoto University Lecturer
Show all
Association Membership(s) (7)：
International Society of Differentiation ,  International Society for Stem Cell Research ,  American Society of Nephrology ,  Japan Diabetes Society ,  Japanese Society for Regenerative Medicine ,  Japanese Society for Dialysis Therapy ,  Japanese Society of Nephrology
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