Rchr
J-GLOBAL ID:200901043405257911   Update date: Sep. 02, 2024

Ohashi Toya

オオハシ トウヤ | Ohashi Toya
Affiliation and department:
Job title: Professor
Research field  (3): Fetal medicine/Pediatrics ,  Genetics ,  Medical biochemistry
Research keywords  (3): Gene Therpay ,  Inborn Error of metabolism ,  Pediatrics
Research theme for competitive and other funds  (48):
  • 2019 - 2022 細胞送達能を高めた改変型酵素を用いるムコ多糖症II型の造血幹細胞遺伝子治療法開発
  • 2018 - 2021 Development of Hematopoietic Stem Targeted Gene Therapy for GM1-gangliosidosis
  • 2018 - 2020 GM1ガングリオシドーシスの造血幹細胞を標的とした遺伝子治療法の開発
  • 2017 - 2020 ライソゾーム病(ファブリ病含む)に関する調査研究
  • 2017 - 2020 小児神経疾患・先天代謝異常症に対する遺伝子治療法開発
Show all
Papers (178):
  • Takashi Higuchi, Yohta Shimada, Yukari Takahashi, Fusao Kato, Toya Ohashi, Hiroshi Kobayashi. Restoration of peripheral neuropathy in Fabry mice via intrathecal administration of an adeno-associated virus vector encoding mGLA cDNA. Molecular Genetics and Metabolism. 2024. 143. 1-2. 108545-108545
  • Takashi Shimazaki, Yuri Shimura, Toya Ohashi, Hideki Nakamura, Yuiko Asakawa, Kinu Takahashi. Cross-sectional study to identify health literacy, health behavior, and quality of life in Chofu and Komae cities in Japan: Formative research in community-based nursing practice. Public health nursing (Boston, Mass.). 2024
  • Jin Ogata, Yohta Shimada, Toya Ohashi, Hiroshi Kobayashi. Usefulness of antibody-drug conjugate as preconditioning for hematopoietic stem cell-targeted gene therapy in wild-type and Fabry disease mouse models. Molecular Genetics and Metabolism. 2024. 142. 3. 108494-108494
  • 櫻井 謙, 西山 由梨佳, 畑 純一, 吉丸 大輔, 小林 正久, 小林 博司, 岡野 ジェイムス洋尚, 大橋 十也, 大石 公彦. 磁気共鳴画像の脳領域別体積測定法を用いたファブリー病の四肢末端痛に関連する病変部位の同定. 日本先天代謝異常学会雑誌. 2022. 38. 180-180
  • Yohta Shimada, Natsumi Ishii, Takashi Higuchi, Motohito Goto, Toya Ohashi, Hiroshi Kobayashi. A novel preclinical model of mucopolysaccharidosis type II for developing human hematopoietic stem cell gene therapy. Gene therapy. 2022
more...
MISC (528):
  • Shirai Yoshihiro, Sugano Hiroshi, Sato Shun, Hamatani Shigeharu, Horiuchi Takashi, Saito Nobuhiro, Hamura Ryoga, Taniai Tomohiko, Yanagaki Mitsuru, Takada Naoki, et al. Prognostic significance of thrombomodulin expression in pancreatic cancer(和訳中). 日本肝胆膵外科学会・学術集会プログラム・抄録集. 2021. 32回. 368-368
  • Mitsuru Yanagaki, Yoshihiro Shirai, Ryoga Hamura, Tomohiko Taniai, Yohta Shimada, Takashi Horiuchi, Naoki Takada, Nobuhiro Saito, Toya Ohashi, Toru Ikegami. Functional analysis of sphingolipid metabolism-related cell apoptosis in pancreatic cancer cells. CANCER SCIENCE. 2021. 112. 440-440
  • 三浦茜, 岡部匡裕, 春原浩太郎, 山本泉, 坪井伸夫, 大橋十也, 井田博幸, 衞藤義勝, 横尾隆. 酵素補充療法を行ったファブリー病7例の長期腎予後と腎組織学的変化の関連性. 日本腎臓学会誌(Web). 2021. 63. 4
  • Masayoshi Yamaoka, Yasuharu Akasaki, Jun Takei, Masaharu Akiyama, Tetsunori Tasaki, Toya Ohashi, Hiroyuki Ida, Takaaki Yanagisawa. PHASE I/II TRIAL OF IMMUNOTHERAPY WITH FUSIONS OF DENDRITIC CELLS AND TUMOR CELLS FOR RELAPSED OR REFRACTORY BRAIN TUMORS IN CHILDREN AND YOUNG ADULTS. NEURO-ONCOLOGY. 2020. 22. 362-362
  • Tomohiko Taniai, Yoshihiro Shirai, Yohta Shimada, Ryoga Hamura, Mitsuru Yanagaki, Naoki Takada, Kazuhito Tsuboi, Yasuo Okamoto, Toya Ohashi, Katsuhiko Yanaga. Inhibition of Sphingolipid Metabolism Has Ceramide-Induced Anti-Tumor Effect on Pancreatic Cancer Cells. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. 2020. 231. 4. S270-S270
more...
Books (15):
  • イラストレイテッド統合臨床基礎医学
    丸善出版 2018 ISBN:9784621302446
  • ファブリー病
    ドクターサロン 2018
  • 連載 ノーベル賞と小児疾患【第6回】1974年ノーベル生理学・医学賞 リソソーム, ペルオキシソームの発見 そしてオートファジーの名づけの親,
    小児内科 2018
  • 特集 先端医療の現状と腎疾患への応用【先端医療の各論】遺伝子治療の現状,
    腎と透析 2018
  • 特集 小児診療ガイドラインの読み解き方-ガイドラインの背景, 使い方を中心に 序-今回の企画について,
    小児内科 2018
more...
Lectures and oral presentations  (84):
  • Fabry病の診断と治療
    (東京Webセミナー 2020)
  • 遺伝子治療の最前線~遺伝性疾患を中心に~, (特別講演)
    (第112回東海臨床遺伝・代謝談話会 2020)
  • Current status of Japanese gene and cell therapy.
    (International Forum on Regulatory Science for Advanced Therapy Medicinal Products (ATMPs))
  • リプレガルの市販後調査, (ランチョンセミナー3 ファブリー病Update)
    (第61回日本先天代謝異常学会総会)
  • 先天代謝異常症に対する遺伝子治療の現状,(特別講演1)
    (第61回日本先天代謝異常学会総会)
more...
Education (1):
  • 1975 - 1981 The Jikei University School of Medicine Faculty of Medicine
Professional career (1):
  • Doctor of Medical Science
Work history (13):
  • 2021/04 - 現在 The Jikei University School of Nursing Department of Human Health Science and Therapeutics Professor
  • 2019/04 - 2022/03 The Jikei University School of Medicine Vice President
  • 2014/04 - 2021/03 The Jikei University School of Medicine Research Center for Medical Sciences Director
  • 2007/08 - 2021/03 Research Center for Medical Sciences, The Jikei University School of Medicine Division of Gene Therapy, Department of Pediatrics Professor
  • 2001/08 - 2007/07 Jikei University
Show all
Committee career (7):
  • 2007/06 - 現在 Japan Society of Gene and Cell Therapy Board of directors
  • 1996 - 現在 Japanese society of Inborn error of metabolism Councilor
  • 2008/06 - 2015/05 American Society of Geen Therapy Membership committee member
  • 2003/01 - 2015/05 European Society of Gene Therapy Scientific committee member
  • 2004/04 - 2014/04 Japanese Society of Pediatrics Representative
Show all
Awards (7):
  • 2019/10 - 日本先天代謝異常学会 学会賞
  • 2011/03 - 2nd Prize Poster Group Basic Science 9th international symposium on lysosomal storage diseases in Madrid, Spain
  • 2009/03 - 2nd Prize Poster Group Basic Science 9th international symposium on lysosomal storage diseases in Frankfurt, Germany, 2009
  • 2008/10 - Poster award, 9th European Round Table on Fabry disease, Athens, Greece
  • 2007/03 - 小児医学 川野賞
Show all
Association Membership(s) (6):
日本先天代謝異常学会 ,  日本小児科学会 ,  日本遺伝子細胞治療学会 ,  The Japan Society of Gene Therapy ,  The Japan Pediatric Society ,  Japanese Society of Inherited Metabolic Disease
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page