Research field (4)：
Immunology
, Allergies and connective tissue disease
, Experimental pathology
, Parasitology
Research keywords (3)：
免疫プロテアソーム
, インフラマソーム
, 自己炎症
Research theme for competitive and other funds (3)：
2022 - 2025 免疫プロテアソームの機能異常による自己炎症病態誘導機構の解析
2019 - 2022 Analysis of the mechanism of autoinflammatory disorder induction due to proteasome dysfunction
2016 - 2019 Analysis of the mechanism of autoinflammatory disorder induction due to proteasome dysfunction
Papers (18)：
Thiranut Jaroonwitchawan, Hideki Arimochi, Yuki Sasaki, Chieko Ishifune, Hiroyuki Kondo, Kunihiro Otsuka, Shin-ichi Tsukumo, Koji Yasutomo. Stimulation of the farnesoid X receptor promotes M2 macrophage polarization. Frontiers in Immunology. 2023. 14
Yuki Sasaki, Hideki Arimochi, Kunihiro Otsuka, Hiroyuki Kondo, Shin-Ichi Tsukumo, Koji Yasutomo. Blockade of the CXCR3/CXCL10 axis ameliorates inflammation caused by immunoproteasome dysfunction. JCI insight. 2022. 7. 7
Michittra Boonchan, Hideki Arimochi, Kunihiro Otsuka, Tomoko Kobayashi, Hisanori Uehara, Thiranut Jaroonwitchawan, Yuki Sasaki, Shin-Ichi Tsukumo, Koji Yasutomo. Necroptosis protects against exacerbation of acute pancreatitis. Cell death & disease. 2021. 12. 6. 601-601
Yuki Sasaki, Kunihiro Otsuka, Hideki Arimochi, Shin Ichi Tsukumo, Koji Yasutomo. Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation. Frontiers in Immunology. 2020. 11
