Rchr
J-GLOBAL ID：200901043945356552   Update date: Feb. 01, 2024

Kozaki Ken'ichi

コザキ ケンイチ | Kozaki Ken'ichi
Affiliation and department：
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Dental Pharmacology

About Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Dental Pharmacology


Job title： Professor
Research field  (7)： Pathobiochemistry ,  Oral medicine ,  Oral medicine (pathology) ,  Tumor diagnostics and therapeutics ,  Experimental pathology ,  Obstetrics and gynecology ,  Fetal medicine/Pediatrics
Research keywords  (37)： がん抑制遺伝子 ,  癌浸潤・転移 ,  がん遺伝子 ,  癌抑制遺伝子 ,  マウス皮下移植自然転移モデル ,  術後再発 ,  EPC-1 ,  血管新生 ,  cyclooxygenase2 ,  エピゲノム異常 ,  網羅的発現解析 ,  リンパ行性転移 ,  コラーゲン ,  capsin ,  COX-2選択的阻害剤 ,  DNA過剰メチル化 ,  エナメル上皮腫 ,  REDF ,  治療ゲノム学 ,  マウス皮下移植モデル ,  リンパ節転移 ,  扁平上皮 ,  miR-137 ,  miR-193a ,  DNAメチル化異常 ,  artificial tongue ,  Palatal Augmentation Prosthesis ,  squamous cell carcinoma ,  oral cancer ,  extracellular matrix ,  molecular target ,  microRNA ,  metastasis ,  epigenome ,  genome ,  分子腫瘍学 ,  molecular oncology
Research theme for competitive and other funds  (17)：
  • 2014 - 2017 Integrative screening of cancer-associated microRNAs for medical application to RNA-based therapeutics
  • 2014 - 2016 Establishment of gene promoter activity detection system for separation of viable and nonviable cells
  • 2011 - 2014 Integrative screening of tumor-suppressive microRNAs for medical application to RNA-based therapeutics
  • 2010 - 2013 Development of diagnostic tools for personalized cancer medicine by genomic and epigenomic analyses
  • 2008 - 2011 Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
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Papers (63)：
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MISC (10)：
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Patents (5)：
Books (2)：
  • 肝細胞癌の早期診断 : 画像と分子マーカー : 厚生労働科学研究費補助金(肝炎等克服緊急対策研究事業)/ 有井滋樹, 松井修代表研究者監・編集
    アークメディア 2012 ISBN:9784875831570
  • Transplants and implants in otology II
    Kugler Publications 1992 ISBN:9062990843
Lectures and oral presentations  (10)：
  • Function-based screening of EMT-suppressive microRNA by CDH1/E-cadherin-promoter activity
    (Symposia “MicroRNA for cancer therapy and diagnosis”, 72st Annual Meeting of Japanese Cancer Association 2013)
  • Function-based screening of EMT-suppressive microRNA in cancer cells.
    (2013 SNUCRI & SNUCH Cancer Symposium 2013)
  • Methylation-based screening of tumor-suppressive microRNAs in cancer cells
    (Symposia “Recent progress of non-coding RNA and cancer”, 71st Annual Meeting of Japanese Cancer Association 2012)
  • Function-based screening of tumor-suppressive microRNAs silenced by DNA hypermethylation in cancer cells
    (Symposia “Cancer epigenetics: Breakthroughs in basic research and clinical applications”, 70th Annual Meeting of Japanese Cancer Association 2011)
  • Function-based screening of tumor-suppressive microRNAs silenced by DNA hypermethylation in cancer cells
    (2011)
ｍore...
Works (2)：
  • がん細胞の病態特異的DNAメチル化異常による悪性形質獲得機構の解明
    小崎 健一
  • 癌抑制遺伝子型microRNAの統合的スクリーニングと核酸医薬への応用
    小崎 健一
Education (4)：
  • 1990 - 1994 Nagoya University Graduate School of Medicine Department of Oral Surgery
  • - 1994 Nagoya University School of Medicine / Graduate of Medicine Doctoral Course at the Graduate School of Medicine, Nagoya Univercity Oral and Maxillofacial Surgery
  • 1983 - 1989 Hiroshima University Faculty of Dentistry
  • - 1989 Hiroshima University Scool of Dentistry
Professional career (1)：
  • Doctor of Medical Science (Nagoya University School of Medicine/Graduate School of Medicine)
Work history (8)：
  • 2014/04 - 現在 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Dental Pharmacology Professor
  • 2010/06 - 2014/03 Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University Associate Professor
  • 2005/05 - 2010/05 Department of Genome Medicine, Hard Tissue Genome Research Center, Tokyo Medical and Dental University Associate Professor
  • 2004/04 - 2005/04 Department of Pharmacology, Osaka Dental University Associate Professor
  • 2001/01 - 2004/03 Department of Pathology, Aichi Medical University School of Medicine Assistant Professor
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Committee career (4)：
  • 2014/06 - 現在 Japanese Association for Oral Biology Councilor member
  • 2014/06 - 現在 歯科基礎医学会 評議員
  • 2011/01 - 現在 日本癌学会 評議員
  • 2011/01 - 現在 Japanese Cancer Association Councilor member
Awards (2)：
  • 2012/11 - Osaka Cancer Research Foundation basic and clinical cancer research projects
  • 2001/11 - Kowa Life Science Foundation Kowa Life Science Foundation Molecular mechanism and suppression of tumor growth via apoptosis induced specifically to in endothelial cells by anti-angiogenic factor caspin/PEDF/EPC-1
Association Membership(s) (4)：
JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE CANCER ASSOCIATION
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