2018 - 2022 A life course worksite-based cohort study of frailty and participation from adulthood until after retirement
2018 - 2021 高血圧による非アルコール性脂肪性肝炎発症・進展とその作用機序の解明
2014 - 2018 Spatial and genetic epidemiological study on the pathogenesis of obesity and diabetes
2015 - 2017 Application of novel mass spectrometric techniques for highly sensitive, specific and speedy identification of new psychoactive substances in human specimens
2015 - 2017 New prevention strategies for non-alcoholic steatohepatitis - a study on the importance of blood pressure and nutritional management
2013 - 2015 A study to clarify the mechanism of non-alcoholic steatohepatitis using 3 different strains of rats fed with high fat and cholesterol diet
2012 - 2015 A study for developing a risk assessment battery for occupational trichloroethylene hypersensitivity syndrome
2012 - 2014 Analysis of specific protein to hypersensitivity induced by trichloroethylene
2011 - 2013 Molecular mechanism for prevention of high-fat and -cholesterol-induced fibrotic steatohepatitis and development of the non-invasive biomarker
2010 - 2011 Genetic and epigenetic differences in cholesterol kinetics in relation to NASH development between SHRSP and SHRSP5/Dmcr rat
2009 - 2010 コレステロール動態を標的としたNASHの発症要因の解明と新たな予防法の確立
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Papers (78)：
Tomoko Misawa, Takumi Kagawa, Nobutaka Ohgami, Akira Tazaki, Shoko Ohnuma, Hisao Naito, Dijie Chen, Yishuo Gu, Takashi Tamura, Kenji Wakai, et al. Elevated level of urinary tellurium is a potential risk for increase of blood pressure in humans and mice. Environment international. 2024. 188. 108735-108735
Takumi Kagawa, Nobutaka Ohgami, Tingchao He, Akira Tazaki, Shoko Ohnuma, Hisao Naito, Ichiro Yajima, Dijie Chen, Yuqi Deng, Takashi Tamura, et al. Elevated arsenic level in fasting serum via ingestion of fish meat increased the risk of hypertension in humans and mice. European heart journal open. 2023. 3. 5. oead074
Tamie Nakajima, Hailan Wang, Yuan Yuan, Yuki Ito, Hisao Naito, Yoshiyuki Kawamoto, Kozue Takeda, Kiyoshi Sakai, Na Zhao, Hongling Li, et al. Increased serum anti-CYP2E1 IgG autoantibody levels may be involved in the pathogenesis of occupational trichloroethylene hypersensitivity syndrome: a case-control study. Archives of toxicology. 2022. 96. 10. 2785-2797
Hypertension and high-fat-cholesterol dietary intake respectively increased Cyp7a1 promoter methylation in the liver of adult rats.
(2018)
Inhibition of detoxification enzyme is involved in development of high-fat-c holesterol diet-induced liver fibrosis in rats fed high-fat-cholesterol diet
(2017)
Association of autophagy and endoplasmic reticulum stress in the fibrotic de velopment by high-fat and -cholesterol diet in SHRSP5/Dmcr
(The 86th Annual Meeting of the Japanese Society for Hygiene 2016)
1992 - 1998 Nagoya University Graduate School of Medicine
Professional career (1)：
博士(医学) (名古屋大学)
Work history (3)：
2020/04 - 現在 Kinjo Gakuin University Department of Food and Nutritional Environment, College of Human Life and Environment Professor
2015/01 - 2020/03 Fujita Health University School of Medicine Department Public Health Senior Assistant Professor
2009/05 - 2014/12 Nagoya University Graduate Scool of Medicine Eepartment of Occupational and Environmental Health Assistant Professor
Committee career (2)：
2017/03 - 現在 日本産業衛生学会 許容濃度等委員会起案委員
2016/11 - 現在 日本産業衛生学会 代議員
Association Membership(s) (5)：
DISEASE MODEL COOPERATIVE RESARCH ASSOCITATION (DMCRA)
, JAPAN EPIDEMIOLOGICAL ASSOCIATION
, THE JAPANESE SOCIETY FOR HYGIENE
, JAPAN SOCIETY FOR OCCUPATIONAL HEALTH
, Society for Hypertension Related Disease Model Research
