Rchr
J-GLOBAL ID：200901044060527950   Update date: Aug. 27, 2024

Tanaka Keiji

タナカ ケイジ | Tanaka Keiji
Affiliation and department：
Tokyo Metropolitan Institute of Medical Science

About Tokyo Metropolitan Institute of Medical Science


Homepage URL  (2)： http://www.igakuken.or.jp/pro-meta/ ,  http://www.rinshoken.or.jp/
Research field  (1)： Molecular biology
Research keywords  (6)： プロテアソーム ,  ユビキチン ,  蛋白質分解 ,  Proteasome ,  Ubiquitin ,  Proteolysis
Research theme for competitive and other funds  (48)：
  • 2022 - 2025 プロテアソーム:相分離とユビキチンが拓く生理病態学
  • 2019 - 2022 Cell Biology of Proteasomes
  • 2014 - 2019 The Proteasome: Mechanistic Actions and In-depth Physiopathological Analyses
  • 2016 - 2018 リン酸化ユビキチンを手がかりにマイトファジーの全貌にせまる
  • 2013 - 2018 Multidisciplinary research on autophagy: from molecular mechanisms to disease states
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Papers (602)：
  • Yukiko Yoshida, Tsuyoshi Takahashi, Nozomi Ishii, Ichiro Matsuo, Satoshi Takahashi, Haruka Inoue, Akinori Endo, Hikaru Tsuchiya, Meari Okada, Chikara Ando, et al. Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation. Molecular Cell. 2024. 84. 16. 3115-3127.e11
  • Aiko Watanabe, Fumika Koyano, Kenichiro Imai, Yohei Hizukuri, Shizuka Ogiwara, Tomoya Ito, Jun Miyamoto, Chihiro Shibuya, Mayumi Kimura, Kazuya Toriumi, et al. The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA. The Journal of biological chemistry. 2024. 107476-107476
  • Nodoka Nago, Shigeo Murata, Keiji Tanaka, Nobuyuki Tanahashi. Changes in brain proteasome dynamics associated with aging. Genes to Cells. 2024
  • Akinori Endo, Toshiaki Fukushima, Chikage Takahashi, Hikaru Tsuchiya, Fumiaki Ohtake, Sayaka Ono, Tony Ly, Yukiko Yoshida, Keiji Tanaka, Yasushi Saeki, et al. USP8 prevents aberrant NF-κB and Nrf2 activation by counteracting ubiquitin signals from endosomes. Journal of Cell Biology. 2024. 223. 3
  • Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano. Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method. The Journal of biological chemistry. 2023. 299. 2. 102822-102822
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MISC (322)：
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Education (4)：
  • The University of Tokushima
  • 徳島大学大学院医学研究科博士課程中退
  • The University of Tokushima
  • Graduate School of Medicine, The University of Tokushima
Professional career (1)：
  • ph. D. (The University of Tokushima)
Work history (10)：
  • 2018/04 - 現在 Tokyo Metropolitan Institute of Medical Science
  • 2016/04 - 2018/03 Tokyo Metropolitan Institute of Medical Science
  • 2012/04 - 2016/03 公益財団法人東京都医学総合研究所 所長(理事兼任)
  • 2011/04 - 2012/03 Tokyo Metropolitan Institute of Medical Science
  • 2006/04 - 2011/03 , Tokyo Metropolitan Institute of Medical Science
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Committee career (1)：
  • 2003 - 日本蛋白質科学会 理事
Awards (16)：
  • 2017 - 第1回日本医療研究開発大賞 総理大臣賞
  • 2014 - Nobel Forum Lecture at Karolinska Institute
  • 2014 - 「文化功労者」顕彰
  • 2010 - 日本内分泌学会マイスター賞
  • 2010 - 慶應医学賞
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Association Membership(s) (9)：
日本蛋白質科学会 ,  日本免疫学会 ,  日本分子生物学会 ,  日本生化学会 ,  日本癌学会 ,  The Japanese Society of Immunology ,  Japanese Molecular Biology Association ,  Japanese Cancer Association ,  Japanese Biochemical Society
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