Rchr
J-GLOBAL ID:200901044085859922
Update date: Feb. 01, 2024
Iwakiri Dai
イワキリ ダイ | Iwakiri Dai
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Affiliation and department:
Hokkaido University Institute for Genetic Medicine
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Detailed information
Research field (2):
Gastroenterology
, Virology
Research keywords (30):
EBウイルス
, EBER
, 胃がん
, TLR3
, 自然免疫
, IGF-1
, RIG-I
, 上咽頭がん
, LMP2A
, EBV
, FGFレセプター
, 細胞内シグナル伝達
, 消化管上皮細胞
, 上咽頭癌
, RLG-I
, 胃癌
, IGF-I
, anoikis
, FGF
, 上部消化管学(食道、胃、十二指腸)
, 細胞分化誘導
, トランスフォーメーション
, 小RNA
, BARF1
, Bリンパ球
, インターフェロン
, 組み換えウイルス
, loxPシステム
, 発がん
, 組換えウイルス
Research theme for competitive and other funds (6):
2014 - 2016 Mechanisms of EBV-mediated gastric carcinogenesis through the exosome-induced signaling.
2011 - 2013 Mechanism of EBV-mediated gastric carcinogenesis depending on TLR3 signals
2008 - 2010 Clarification of the mechanism of EBV-small RNA-mediated gastric carcinogenensis through the activation of innate immune signals.
2006 - 2007 Study of mechanism of Epstein-Barr virus-encoded small RNA-mediated gastric carcinogenesis
2004 - 2005 Study of mechanism of gastric carcinogenesis associated with EBV-mediated IGF-1 induction
2002 - 2003 FGFレセプターを介した消化管上皮細胞分化誘導シグナルの解析
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Papers (10):
Dai Iwakiri. Epstein-Barr Virus-Encoded RNAs: Key Molecules in Viral Pathogenesis. CANCERS. 2014. 6. 3. 1615-1630
Iwakiri D. [Molecular mechanisms of Epstein-Barr virus-mediated carcinogeneis]. Uirusu. 2014. 64. 1. 49-56
Dai Iwakiri, Takeharu Minamitani, Mrinal Samanta. Epstein-Barr Virus Latent Membrane Protein 2A Contributes to Anoikis Resistance through ERK Activation. JOURNAL OF VIROLOGY. 2013. 87. 14. 8227-8234
Kei Sato, Naoko Misawa, Chuanyi Nie, Yorifumi Satou, Dai Iwakiri, Masao Matsuoka, Rei Takahashi, Kiyotaka Kuzushima, Mamoru Ito, Kenzo Takada, et al. A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice. BLOOD. 2011. 117. 21. 5663-5673
Takeharu Minamitani, Dai Iwakiri, Kenzo Takada. Adenovirus Virus-Associated RNAs Induce Type I Interferon Expression through a RIG-I-Mediated Pathway. JOURNAL OF VIROLOGY. 2011. 85. 8. 4035-4040
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Professional career (1):
医学博士
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