Rchr

J-GLOBAL ID：200901045388517907 Update date: Nov. 11, 2024

Shiota Kohei

シオタコウヘイ | Shiota Kohei

Affiliation and department：
Homepage URL (1)： http://www.jnhf.or.jp/

Research field (2)： Fetal medicine/Pediatrics , Anatomy

Research keywords (9)： Developmental Biology , 解剖学 , 発生学 , 先天異常学 , 発生生物学 , Anatomy , Embryology , Teratology , Birth Defects

Research theme for competitive and other funds (50)：

2008 - 2010 Cyp26(レチノイン酸分解酵素)の役割を中心とした皮膚発生における分子機構
2008 - 2010 Roles of signaling molecules in forebrain morphogenesis
2008 - 2009 モルフォゲンの濃度勾配ロバストネス保証および分化運命決定における閾値の分子機構
2007 - 2009 Gene-environmental interaction in early morphogenesis of the brain and developmental anomalies due to its disturbance
2006 - 2008 Development of new in vitro analytic systems to clarify the mechanism underlying normal palatogenesis and cleft palate formation

2005 - 2008 ヒト胚の形態発生に関する三次元データベース

2005 - 2008 3D database of morphogenesis in human embryos

2006 - 2007 Molecular mechanisms of forebrain morphogenesis

2005 - 2006 尿道下裂の分子機序の解明

2004 - 2005 Study on the mechanisms by which cleft palate shows its phenotypic polymorphism in mice

2002 - 2004 内耳原基の器官培養系を用いた内耳の形態形成機構と内耳奇形発生のメカニズムの解明

2002 - 2004 Development of three-dimensional image programs for research and education of human embryology

2001 - 2003 Establishing a database of MR microscopic images of human embryos and an educational system for human embryology

2001 - 2003 Roles of Fgf, Wnt and Shh signals in vertebrate morphogenesis and their interactions

2001 - 2002 Regulation of neural differentiation by the transcription factor HES and the receptor Notch in mammals

2000 - 2002 Analysis of the mechanisms of mammalian palate and limb morphogenesis

2000 - 2001 胎児の肺原基における初期分枝パターンの数理モデル化とその実験的検証

1999 - 2000 なぜ覚せい剤はなかなか止められないのか?脳報酬系機能からの解析

1999 - 2000 転写制御因子HESとその受容体Notchによる初期神経分化の制御機構

1998 - 2000 Developmental and molecular cell biological study of the mechanisms of limb differentiation

1998 - 1999 Study on the expression of matrix-degrading enzymes and programmed cell death during mammalian development

1998 - 1999 Developmental Brain Disorders due to Physical Agents

1997 - 1999 Studies on the development of new diagnosis and therapy for panaeatic cancer.

1997 - 1998 Analysis of spermatogenesis & meiosis using knockout mice

1997 - 1998 Analysis of the Notch-HES pathway that regulates mammalian neurogenesis

1996 - 1997 Morphological and molecular cell biological study of apoptosis in mammalian morphogenesis

1995 - 1996 Apoptosis and epithelium-mesenchyme interaction during mammalian morphogenesis

1995 - 1996 Molecular Diagnosis of Genic Abnormalities using Human Tissue Materials

1995 - 1996 Development of Education and Research Support System for Human Embryology using Three-Dimensional Fetus Image Reconstruction

1994 - 1995 Apoptsis in mammalian morphogenesis.

1994 - 1995 Epidemiological Investigation on Environmental Pollution

1993 - 1994 Spermatogenic cell specific gene expression in mammals : Enzymes of glycolysis

1993 - 1994 Development of alternatives to animal experiments with in vitro cultures of undifferentiated embryonic cells and organ primodia

1992 - 1993 Study on the role of epidermal growth factor receptor and protooncogenes in mammalian morphogenesis

1992 - 1993 Mechanisms and prevention of developmental brain disorders due to prenatal effects of physical agents

1992 - 1992 未分化胎児組織の移植法を用いた発がんと発生異常の相関に関する実験的研究

1991 - 1991 未分化胎児組織の移植法を用いた発がんと発生異常の相関に関する実験的研究

1990 - 1991 Immunohistochemical study on the expression and localization of the epidermal growth factor receptor during morphogenesis

1988 - 1989 Research on the differentiation of fetal tissues by means of heterotransplantation and its application to developmental toxicology

1985 - 1987 Experimental study on the embryotoxic effects of hyperthermia and their prevention

1986 - 1986 ヒトにおける発生毒性に関する感受性の推定方法

1985 - 1985 ヒトにおける発生毒性に関する感受性の推定方法

1971 - 実験奇形学

1971 - 先天異常の遺伝疫学

1971 - 形態形成メカニズム

1971 - ヒト正常及び異常発生学

1971 - Experimental teratology

1971 - Genetic epidemiology of human birth defects

1971 - Mechanisms of morphogenesis

1971 - Normal and abnormal development of the human

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Papers (199)：

Francisco J R Paumgartten, Wilma De Grava Kempinas, Kohei Shiota. Viral infections, vaccines and antiviral drugs in pregnancy and the development of the conceptus. Reproductive toxicology (Elmsford, N.Y.). 2022
Kohei Shiota. A life-table analysis of the intrauterine fate of malformed human embryos and fetuses. Birth defects research. 2021. 113. 8. 623-632
Kohei Shiota. To Err is Human: The Complex Nature of Human Reproduction and Prenatal Development. Creative Complex Systems. 2021. 17-31
Roland Solecki, Martina Rauch, Andrea Gall, Jochen Buschmann, Rupert Kellner, Olena Kucheryavenko, Anne Schmitt, Nathalie Delrue, Weihua Li, Jingying Hu, et al. Update of the DevTox data database for harmonized risk assessment and alternative methodologies in developmental toxicology: Report of the 9th Berlin Workshop on Developmental Toxicity. Reproductive toxicology (Elmsford, N.Y.). 2019. 89. 124-129
Yu Abe, Paul Kruszka, Ariel F Martinez, Erich Roessler, Kohei Shiota, Shigehito Yamada, Maximilian Muenke. Clinical and Demographic Evaluation of a Holoprosencephaly Cohort From the Kyoto Collection of Human Embryos. Anatomical record (Hoboken, N.J. : 2007). 2018. 301. 6. 973-986

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MISC (95)：

Philip Marx-Stoelting, Marize de L.M. Solano, Hiroaki Aoyama, Ralf H. Adams, Anna Bal-Price, Jochen Buschmann, Ibrahim Chahoud, Ruth Clark, Tian Fang, Michio Fujiwara, et al. 25th anniversary of the Berlin workshop on developmental toxicology: DevTox database update, challenges in risk assessment of developmental neurotoxicity and alternative methodologies in bone development and growth. Reproductive Toxicology. 2021. 100. 155-162
駒田致和, 藤山総子, 山田重人, 塩田浩平, 長尾哲二. ニトロソ尿素の胎児期曝露によって誘発されるマウス小頭症発症機序. 解剖学雑誌. 2011. 86. 2. 55-55
S. Yamada, T. Kameda, M. Takahashi, T. Funatomi, S. Mizuta, Y. Matsuda, T. Haishi, K. Kose, T. Matsuda, M. Minoh, et al. Construction and Application of Human Embryo Database. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY. 2011. 91. 5. 345-345
高桑徹也, 山田重人, 上部千賀子, 塩田浩平, 巨瀬勝美. "京都コレクション"を用いたヒト胚子3次元立体像(Virtual Human Embryo)の作成. 日本遺伝カウンセリング学会誌. 2011. 32. 2. 77-77
高桑徹也, 山田重人, 上部千賀子, 塩田浩平, 巨瀬勝美. "京都コレクション"を用いたヒト胚子3次元立体像(Virtual Human Embryo)の作成. 家族性腫瘍. 2011. 11. 2. A77-A77

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Books (19)：

イラストレイテッド解剖学
2020
カラー図解人体発生学講義ノート(第2版)
金芳堂 2017
Gray's Anatomy for Students (3rd edition)
2016
カラー図解人体発生学講義ノート
金芳堂 2015
Gray's Atlas of Anatomy (2nd edition)
2015

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Works (4)：

ヒト胎児発生のイメージング
2004 -
Imaging of human prenatal development
2004 -
妊娠中の高体温が胎児の発生に及ぼす影響
1985 -
Effects of Heat on Embryos and Fetuses
1985 -

Education (2)：

1972 - 1976 Kyoto University
1965 - 1971 Kyoto University School of Medicine

Professional career (1)：

Ph.D.(D.Med.Sc.) (Kyoto University)

Work history (23)：

2020 - 現在 Shiga University of Medical Science Professor Emeritus
2009 - 現在 Kyoto University Professor Emeritus
2021 - 2022 国立大学法人滋賀大学理事(非常勤)
2014 - 2020 国立大学法人滋賀医科大学学長
2012 - 2014 京都大学大学院総合生存学館特定教授

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Committee career (19)：

2016 - 現在 International Academy of Perinatal Medicine Honorary Fellow
2015 - 現在 (公財)京都大学教育研究振興財団評議員
2015 - 現在 (公財)ひと•健康•未来研究財団理事長
2014 - 現在 (公財)大原記念倉敷中央病院機構理事
2021 - 2022 国立大学法人滋賀大学理事(非常勤)

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Association Membership(s) (12)：

米国先天異常学会 , 日本発生生物学会 , 日本先天異常学会 , 日本人類遺伝学会 , 日本解剖学会 , 国際発生物学会 , Teratology Society(U.S.A.) , Japanese Teratology Society , Japanese Society of Human Genetics , Japanese Society of Developmental Biologists , Japan Association of Anatomists , International Society of Developmental Biologists

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