Research field (1)：
Pharmaceuticals - health and biochemistry
Research keywords (3)：
saliva
, エキソソーム
, exosome
Research theme for competitive and other funds (4)：
2016 - 2019 Mechanism of mucosal immunity activation by exosome
2013 - 2016 Molecular mechanism and regulation of immune activation cascade by aminopeptidase contained exosome.
分泌小胞エキソソームの構造と機能
exosome
Papers (17)：
Yuko Ogawa, Yuri Miura, Mamoru Ikemoto, Atsushi Ohnishi, Yoshikuni Goto, Kazuma Aoki, Yuki Motokurumada, Yoshihiro Akimoto, Tamao Endo, Masafumi Tsujimoto, et al. Distinguishing two distinct types of salivary extracellular vesicles: a potential tool for understanding their pathophysiological roles. Frontiers in molecular biosciences. 2024. 11. 1278955-1278955
Yuko Ogawa, Yoshihiro Akimoto, Mamoru Ikemoto, Yoshikuni Goto, Anna Ishikawa, Sakura Ohta, Yumi Takase, Hayato Kawakami, Masafumi Tsujimoto, Ryohei Yanoshita. Stability of human salivary extracellular vesicles containing dipeptidyl peptidase IV under simulated gastrointestinal tract conditions. Biochemistry and Biophysics Reports. 2021. 27. 101034-101034
Miho Watanabe-Takahashi, Shinji Yamasaki, Masayuki Murata, Fumi Kano, Jun Motoyama, Jyoji Yamate, Jumpei Omi, Waka Sato, Hirofumi Ukai, Kentaro Shimasaki, et al. Exosome-associated Shiga toxin 2 is released from cells and causes severe toxicity in mice. Scientific Reports. 2018. 8. 1
Goto Y, Ogawa Y, Tsumoto H, Miura Y, Nakamura TJ, Ogawa K, Akimoto Y, Kawakami H, Endo T, Yanoshita R, et al. Contribution of the exosome-associated form of secreted endoplasmic reticulum aminopeptidase 1 to exosome-mediated macrophage activation. Biochimica et biophysica acta. Molecular cell research. 2018. 1865. 6. 874-888
Katsuhiro Isoda, T. Daibo, K. Yushina, Y. Yoshioka, Y. Tsutsumi, Y. Akimoto, H. Kawakami, Y. Taira, I. Taira, R. Yanoshita, et al. Hepatotoxicity, nephrotoxicity, and drug/chemical interaction toxicity of platinum nanoparticles in mice. Pharmazie. 2017. 72. 1. 10-16
