Kamiya Hiroyuki

カミヤヒロユキ | Kamiya Hiroyuki

Affiliation and department：
Job title： Associate Professor

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (6)：ゲノム編集 , 遺伝子治療 , DNA損傷 , DNA damage , Nucleic Acids Chemistry , Gene Therapy

Research theme for competitive and other funds (38)：

2022 - 2025 老化細胞誘発クラスター性変異のNGS解析による放射線発がん機構研究
2022 - 2025 活性酸素と脱アミノ化酵素APOBEC3が誘発する遠隔作用変異の分子機構の解明
2019 - 2022 Molecular mechanisms of action-at-a-distance mutations induced by DNA damage
2017 - 2020 Next generation genome editing without artificial nucleases
2016 - 2019 Molecular mechanisms of action-at-a-distance mutations

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Papers (254)：

Arlet Hernandez, Jenna Hedlich-Dwyer, Saddam Hussain, Hailey Levi, Manoj Sonavane, Tetsuya Suzuki, Hiroyuki Kamiya, Natalie R Gassman. Acute exposure to dihydroxyacetone promotes genotoxicity and chromosomal instability in lung, cardiac, and liver cell models. Toxicological sciences : an official journal of the Society of Toxicology. 2024. 201. 1. 85-102
Tetsuya Suzuki, Saho Yoshida, Hiroyuki Kamiya. Inhibition of Uracil DNA Glycosylase Alters Frequency and Spectrum of Action-at-a-Distance Mutations Induced by 8-Oxo-7,8-dihydroguanine. Biological & pharmaceutical bulletin. 2024. 47. 7. 1275-1281
Yoshihiro Fujikawa, Hidehiko Kawai, Tetsuya Suzuki, Hiroyuki Kamiya. Visualization of oxidized guanine nucleotides accumulation in living cells with split MutT. Nucleic Acids Research. 2024. 52. 11. 6532-6542
Hidehiko Kawai, Kento Sato, Taiki Kato, Hiroyuki Kamiya. Correction of substitution, deletion, and insertion mutations by 5′-tailed duplexes. Journal of Bioscience and Bioengineering. 2024. 137. 3. 157-164
Ruriko Fukushima, Tetsuya Suzuki, Akari Kobayakawa, Hiroyuki Kamiya. Action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine are dependent on APOBEC3. Mutagenesis. 2024. 39. 1. 24-31

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MISC (5)：

Kamiya Hiroyuki. EN-2 Mutations induced by oxidized DNA precursors and their prevention by nucleotide pool sanitization enzymes(JEMS Encouragement Award 2006,Award Lecture). 2006. 35. 60-60
KAMIYA Hiroyuki, KASAI Hiroshi, Hiroyuki Kamiya, Hiroshi Kasai, Department of Environmental Oncology Institute of Industrial Ecological Sciences University of Occupational and Environmental Health, Department of Environmental Oncology Institute of Industrial Ecological Sciences University of Occupational and Environmental Health. Oxidative DNA damage and mechanisms of mutagenesis. Environmental mutagen research communications. 1998. 20. 3. 195-200
KAMIYA Hiroyuki, MURATA-KAMIYA Naoko, OHTSUKA Eiko, Hiroyuki Kamiya, Naoko Murata-Kamiya, Eiko Ohtsuka, Institute of Industrial Ecological Sciences University of Occupational and Environmental Health, Institute of Industrial Ecological Sciences University of Occupational and Environmental Health, Graduate School of Pharmaceutical Sciences Hokkaido University. Mutagenesis by pyrimidine dimers. Environmental mutagen research communications. 1998. 20. 3. 213-220
紙谷浩之, 葛西宏. 活性酸素によって生ずるDNA損傷と誘発される変異 (核酸化学の新展開--新しい機能性分子を求めて) -- (核酸の構造). 蛋白質核酸酵素. 1995. 40. 10. p1571-1577
H. Kamiya, H. Kasai. DNA lesions produced by active oxygen and their induced mutations. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 1995. 40. 10. 1571-1577

Books (2)：

Education (3)：

1988 - 1988 Hokkaido University
1986 - 1988 Hokkaido University
1982 - 1986 Hokkaido University Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

Work history (4)：

Committee career (4)：

Awards (4)：

Association Membership(s) (10)：

Sigma Xi , 日本ゲノム編集学会 , THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY , 日本環境変異原学会 , 日本薬剤学会 , 日本薬学会 , 日本分子生物学会 , 日本癌学会 , 日本DDS学会 , 日本放射線影響学会

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