Rchr
J-GLOBAL ID:200901046238347147   Update date: Nov. 17, 2024

Takai Shinji

タカイ シンジ | Takai Shinji
Affiliation and department:
Job title: Professor
Other affiliations (1):
  • Osaka Medical and Pharmaceutical University  Department of Pharmacology   Professor
Homepage URL  (1): https://www.ompu.ac.jp/u-deps/grd/
Research field  (1): Pharmacology
Research keywords  (2): 薬理学一般 ,  Pharmacology in General
Research theme for competitive and other funds  (48):
  • 2024 - 2027 Clarification of therapeutic strategies and mast cells on salivary gland adenoid cystic carcinoma and oral cancer
  • 2023 - 2027 Development of extracorporeal VAD housing having excellent blood compatibility using anti-fouling peptide immobilization technology
  • 2022 - 2026 Verification of stenosis-preventive effect of bifunctionalized artificial blood vessels utilizing peptide modification technology
  • 2022 - 2025 Possibility of neuroprotection by inhibition of tau phosphorylation - Investigation in optic nerve injury
  • 2022 - 2025 Pathophysiological role of chymase in diabetic complications
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Papers (290):
  • Hiroe Toba, Shinji Takai. Exploring the roles of SPARC as a proinflammatory factor and its potential as a novel therapeutic target against cardiovascular disease. American Journal of Physiology-Heart and Circulatory Physiology. 2024. 327. 5. H1174-H1186
  • Hirofumi Morihara, Shunichi Yokoe, Shigeo Wakabayashi, Shinji Takai. TMEM182 inhibits myocardial differentiation of human iPS cells by maintaining the activated state of Wnt/β-catenin signaling through an increase in ILK expression. FASEB BioAdvances. 2024. 6. 11. 565-579
  • Masanari Yoshimoto, Denan Jin, Hiroshi Sakonjo, Shinji Takai. Renoprotective Effects of Chymase Inhibition on Cisplatin-Induced Nephrotoxicity in Mice. Bulletin of Osaka Medical and Pharmaceutical University. 2024. 70. 1. 25-34
  • Tsunehiko Ikeda, Denan Jin, Shinji Takai, Kimitoshi Nakamura, Emika Nemoto, Shota Kojima, Hidehiro Oku. Blastocyst-like Structures in the Peripheral Retina of Young Adult Beagles. International Journal of Molecular Sciences. 2024. 25. 11. 6045-6045
  • Shimada K, Hirose M, Hamabe L, Takai S, Jin D, Yilmaz Z, Kocaturk M, Tanaka R. Evaluation of Alacepril Administration in Canine Patent Ductus Arteriosus According to Plasma Chymase Activity. Animals. 2024. 14. 7. 1078-1078
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MISC (280):
  • 渡瀬謙仁, 寺井健太郎, 金徳男, 金宮健翁, 中倉兵庫, 柴原伸久, 有馬秀二, 高井真司. ペリオスチンのAVGの狭窄への関与について. 奈良県医師会透析部会誌. 2023. 28. 1
  • 米山弘樹, 北村育子, 植村優希, 吉田彩葉, 豊田美唯, 細畑圭子, 金徳男, 葉山登, 宇佐美吉英, 高井真司. 腎疾患治療薬開発を指向した新規vanin-1阻害剤の創製. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2023. 28th
  • 飯田達也, 細畑圭子, 東悠輔, 林真白, 米山弘樹, 金徳男, 北村育子, 植村優希, 吉田彩葉, 豊田美唯, et al. 新規vanin-1阻害剤の急性腎障害軽減効果の検討. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2023. 28th
  • 寺井 健太郎, 金 徳男, 渡瀬 謙仁, 今川 彰久, 高井 真司. 糖尿病マウスにおけるキマーゼ阻害によるアルブミン尿の減少機序の解明. 糖尿病. 2021. 64. Suppl.1. I-5
  • Keiko Hosohata, Shinji Takai. 食塩感受性高血圧による尿細管障害と非侵襲性バイオマーカー. Precision Medicine. 2021. 4. 69-73
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Patents (15):
  • VANIN-1INHIBITOR
  • Vanin-1 inhibitor
  • Methods for measuring Vanin-1 protein in specimens by immunochromatography and its testing instruments
  • 人工血管、及び人工血管の製造方法
  • 癒着治療薬、癒着の治療方法、術後癒着マーカー、および術後癒着の罹患の可能性を試験する方法
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Books (15):
  • 生体吸収性外科材料の使い方と新しい材料の有用性
    技術情報協会 2024 ISBN:9784867980149
  • Hypertension
    2020
  • カラ-新しい薬理学(教科書)
    西村書店 2018
  • 生体吸収素材の開発と安全性評価
    技術情報協会 2017
  • 実はすごい!ACE阻害薬
    南江堂 2015
more...
Professional career (1):
  • Doctor (Osaka Medical College)
Work history (3):
  • 2023/07 - 現在 Osaka Medical and Pharmaceutical University Department of Pharmacology Professor
  • 2021/04 - 現在 Osaka Medical and Pharmaceutical University Graduate School of Medicine, Department of Innovative Medicine Professor
  • 2014/07 - 2021/03 Osaka Medical College Graduate School of Medicine, Department of Innovative Medicine Professor
Committee career (6):
  • 日本循環薬理学会 幹事
  • 日本病態プロテアーゼ学会 理事
  • 日本心脈管作動物質学会 評議員
  • 日本高血圧学会 評議員・顕彰委員会委員
  • 日本薬理学会 代議員・評議員・研究推進委員会委員・学術企画委員会委員
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Awards (7):
  • 2015 - 日本薬理学会JPS優秀論文賞
  • 2003 - 日本薬理学会学術奨励賞
  • 2003 - Young Investigator's Award fron Japanese Pharmacological Society
  • 2001 - 日本循環薬理学会 Young Investigator's Award
  • 2001 - 心血管病若手奨励賞
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Association Membership(s) (6):
日本病態プロテアーゼ学会 ,  Japanese Association of Cardiovascular Pharmacology ,  日本心脈管作動物質学会 ,  日本高血圧学会 ,  日本薬理学会 ,  American Heart Association
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