Ogawa Mikako

オガワミカコ | Ogawa Mikako

Affiliation and department：
Other affiliations (1)：

浜松医科大学メディカルフォトニクス研究センター訪問共同研究員

Research field (1)： Pharmaceuticals - analytical and physicochemistry

Research theme for competitive and other funds (31)：

2022 - 2026 エネルギー代謝に着目した核医学イメージングによるがん微小環境評価
2022 - 2025 がん特異的糖鎖抗原を用いた小児がんに対する近赤外光線免疫療法の確立:前臨床モデル
2021 - 2025 PET imaging for cancer treatment inducing ferrotosis
2021 - 2024 Development of photoimmunotherapy that not require external light irradiation
2021 - 2024 Ferroptosis imaging with PET: Challenge to assess vulnerability of atherosclerotic plaques

2021 - 2024 Development of photoimmunotherapy via O-glycans and siRNA delivery system using iRGD nanoparticles in lung cancer

2021 - 2024 Establishment of near-infrared photoimmunotherapy targeting CD73 using mouse lung cancer model

2021 - 2023 硬X線による化合物活性化を利用した新しいがん治療法の開拓

2019 - 2022 α線治療はなぜ効くのか?ーがん免疫から迫るー

2019 - 2022 Elucidation of the Mechanism of Photoimmunotherapy Using Molecular Imaging and Development of New Drugs

2018 - 2021 Assessment of unstable plaque by PET, CT, and MRI combination

2018 - 2020 自己会合型環境応答性光音響イメージング剤の開発

2016 - 2019 Cancer therapy by Cerenkov radiation

2016 - 2019 Theranostics by combination with nuclear and optical methods

2015 - 2018 Vulnerability Assessment of Atherosclerosis by PET

2014 - 2018 A potential role of lymphatic vessels in drug delivery system

2014 - 2017 Imaging and Drug Delivery to Sentinel Lymph Node by Using All-In-One Dendrimers

2013 - 2016 Cerenkov luminescence imaging using PET probes

2013 - 2016 development of a novel imaging probe for alteration of mitochondria function based on cancer therapy

2012 - 2016 PET imaging probes for detection and evaluation of atherosclerotic plaques

2011 - 2014 In vivo imaging of the activity of ganma-secretase for amyloid production in Alzheimer's disease

2010 - 2012 development of a novel imaging method for cancer therapy based on alteration of mitochondriafunction

2009 - 2011 Development of a molecular imaging probe for vulnerable plaque imaging

2009 - 2011 Development of novel CT contrast agents with long retention in the vessel

2009 - 2011 Elucidation of biological basis of autism as fatty acid metabolic disease

2007 - 2008 動脈硬化病変に生じる不安定プラークの検出に有用な核医学イメージング剤に関する検討

2005 - 2007 Development of novel evaluation system and radiopharmaceutical for prediction of tumor treatment effect ; especially oxygen effect of tumor therapy

2005 - 2007 Studies on radiopharmaceuticals with mitochondria membrane potential dependent tumor accumulation

2005 - 2006 神経細胞選択的なエネルギー代射活動イメージング法の開発

2005 - 2006 統合失調症の定量的評価を目的とする分子イメージング法の開発研究

2002 - 2004 神経細胞選択的なエネルギー代謝イメージング法の開発

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Papers (201)：

Koki Tsuchiya, Hideo Takakura, Kohei Nakajima, Naoya Ieda, Takashi Kaneko, Takeshi Hirasawa, Masato Kobayashi, Yoshihisa Yamaoka, Miya Ishihara, Tetsuya Taketsugu, et al. Piperazine based pH-responsive cyanine dyes for cancer cell photoacoustic imaging. Journal of Photochemistry and Photobiology A: Chemistry. 2024. 453. 115634-115634
Naoya Ieda, Hideo Takakura, Hirotaka Maeta, Takayuki Ohira, Koki Tsuchiya, Kohei Nakajima, Mikako Ogawa. Investigation of the substituent effect of indocyanine green derivatives for lymph imaging. Bioorganic & Medicinal Chemistry. 2024. 117824-117824
Chie Kojima, Junjie Yao, Kohei Nakajima, Motofumi Suzuki, Ayako Tsujimoto, Yuji Kuge, Mikako Ogawa, Akikazu Matsumoto. Attenuated polyethylene glycol immunogenicity and overcoming accelerated blood clearance of a fully PEGylated dendrimer. International Journal of Pharmaceutics. 2024. 659. 124193-124193
Takahiro Obara, Nanami Kawano, Kengo Tatsumi, Akira Katsuyama, Kohei Nakajima, Mikako Ogawa, Satoshi Ichikawa. Development of small molecule-drug conjugates based on derivatives of natural proteasome inhibitors that exhibit selectivity for PSMA-expressing cancer cells. Bioorganic & Medicinal Chemistry. 2024. 108. 117773-117773
Yuto Goto, Kanta Ando, Hideo Takakura, Kohei Nakajima, Masato Kobayashi, Osamu Inanami, Tetsuya Taketsugu, Mikako Ogawa. Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer. Journal of Photochemistry and Photobiology. 2024. 20. 100230-100230

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MISC (87)：

稲波修, 加藤千博, 安井博宣, 後藤悠人, 小川美香子. 放射線によるDNA損傷は遅延性のミトコンドリア由来の細胞内活性酸素種を上昇させるか?. 日本酸化ストレス学会学術集会プログラム・抄録集. 2023. 76th
山下柾, 松廣志乃, 高倉栄男, 中島孝平, 稲波修, 小川美香子. Analysis of X-ray responsiveness of phthalocyanine derivatives for development of caged compounds that can be used deep in vivo. 日本薬学会年会要旨集(Web). 2023. 143rd
後藤悠人, 高倉栄男, 中島孝平, 稲波修, 小川美香子. Investigation of a reaction mechanism of photoimmunotherapy using ESR. 日本薬学会年会要旨集(Web). 2023. 143rd
稲波修, 榎本将聖, 我喜屋祥, 中島孝平, 小川美香子. Analysis of radiation reaction mechanisms of hypervalent iodine compounds using ESR for the development of radiation-responsive caged compounds. 電子スピンサイエンス学会年会講演要旨集. 2023. 62nd (CD-ROM)
小河原浩輝, 高倉栄男, 中島孝平, 稲波修, 小川美香子. Analysis of azo cleavage reaction for development of X-ray induced caged compounds. 日本薬学会年会要旨集(Web). 2023. 143rd

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Professional career (1)：

博士(薬学) (京都大学)

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