Rchr
J-GLOBAL ID：200901046837018526   Update date: Jul. 16, 2024

Hosoya Ken'ichi

ホソヤ ケンイチ | Hosoya Ken'ichi
Affiliation and department：
University of Toyama Graduate School of Mediceine and Pharmaceutical Sciences

About University of Toyama Graduate School of Mediceine and Pharmaceutical Sciences


Homepage URL  (1)： http://www.pha.u-toyama.ac.jp/phaphzai/index-j.html
Research field  (1)： Clinical pharmacy
Research keywords  (5)： transporter ,  blood-brain barrier ,  blood-retinal barrier ,  Biopharmacy ,  Biopharmaceutics
Research theme for competitive and other funds  (28)：
  • 2022 - 2025 Transport mechanisms of cell-penetrating peptides at the blood-retinal barrier to establish strategies of macromolecular drug delivery
  • 2020 - 2023 血液精巣関門インフラックス輸送機構の解明と精巣内薬物送達への応用
  • 2020 - 2023 血液網膜関門カチオン性物質輸送に寄与する機構としてのMCT9・14の役割解明
  • 2019 - 2022 Establishing ex vivo methods to elucidate efflux transport of drugs at the blood-retinal barrier for retinal drug development
  • 2016 - 2019 Molecular mechanisms of transport function at the BBB in epilepsy for normalizing cerebral PGE2 level
Show all
Papers (214)：
  • Takeru Ito, Yoshiyuki Kubo, Yuma Tega, Shin-Ichi Akanuma, Ken-Ichi Hosoya. Blood-to-Testis Transport of Ribavirin Involves Carrier-Mediated Processes at the Blood-Testis Barrier. Journal of pharmaceutical sciences. 2024
  • Ryuta Jomura, Masaru Sawada, Yuma Tega, Shin-Ichi Akanuma, Masanori Tachikawa, Ken-Ichi Hosoya. Molecular Mechanism of SLC6A8 Dysfunction with c.1699T > C (p.S567P) Mutation in Cerebral Creatine Deficiency Syndromes. Biological & pharmaceutical bulletin. 2024. 47. 1. 187-191
  • Yuma Tega, Toshinari Takeuchi, Masatoshi Nagano, Reina Makino, Yoshiyuki Kubo, Shin-Ichi Akanuma, Ken-Ichi Hosoya. Characterization of LysoTracker Red uptake by in vitro model cells of the outer blood-retinal barrier: Implication of lysosomal trapping with cytoplasmic vacuolation and cytotoxicity. Drug metabolism and pharmacokinetics. 2023. 51. 100510-100510
  • Yuma Tega, Yoshiyuki Kubo, Hiroaki Miura, Kairi Ri, Ayaka Tomise, Shin-Ichi Akanuma, Ken-Ichi Hosoya. Carrier-Mediated Process of Putrescine Elimination at the Rat Blood-Retinal Barrier. International journal of molecular sciences. 2023. 24. 10
  • Yusuke Shinozaki, Yuma Tega, Shin-Ichi Akanuma, Ken-Ichi Hosoya. The Structural Characteristics of Compounds Interacting with the Amantadine-Sensitive Drug Transport System at the Inner Blood-Retinal Barrier. Pharmaceuticals (Basel, Switzerland). 2023. 16. 3
ｍore...
MISC (75)：
  • 久保 義行, 細谷 健一. 血液網膜関門における網膜への薬物輸送メカニズム. Pharm stage. 2017. 17. 1. 73-79
  • Yoshiyuki Kubo, Masakazu Yamamoto, Kensuke Matsunaga, Shin-Ichi Akanuma, Ken-Ichi Hosoya. INVOLVEMENT OF PLASMA MEMBRANE MONOAMINE TRANSPORTER (PMAT/SLC29A4) IN RETINA-TO-BLOOD TRANSPORT OF MPP plus ACROSS THE BLOOD-RETINAL BARRIER. DRUG METABOLISM AND PHARMACOKINETICS. 2017. 32. 1. S100-S101
  • 赤沼 伸乙, 久保 義行, 細谷 健一. タウリンの体内動態とその動態にトランスポーターが果たす役割 (特集 第1回国際タウリン研究会日本部会プロシーディングス). タウリンリサーチ = Japanese journal of taurine research. 2015. 1. 1. 44-46
  • Difference and Similarity between Organic Cation Transports at the Blood-Retinal and -Brain Barriers. 2013. 32. 9. 950-954
  • HOSOYA Ken-ichi. Biopharmaceutical Approach to the Blood-Retinal Barrier Transport. 2006. 66. 5. 332-337
ｍore...
Books (24)：
  • 血液網膜関門における網膜への薬物輸送メカニズム
    PHARM STAGE,17, 73-79 2017
  • クレアチン前駆体-グアニジノ酢酸(GAA)の体内動態と中枢GABA機能
    腎と透析 80, 773-778 2016
  • タウリンの体内動態とその動態にタウリントランスポーターが果たす役割
    タウリンリサーチ,1,44-46 2015
  • The blood-retinal barrier and carnosine, IN: Imidazole Dipeptides: Chemistry, Analysis, Function and Effects, V. R. Preedy (Ed) pp.528-547
    The Royal Society of Chemistry 2015
  • 吸収、わかりやすい生物薬剤学第5版 pp. 13-57
    廣川書店 2014
ｍore...
Education (2)：
  • 1983 - 1985 Josai University Graduate School of Pharmaceutical Sciences
  • 1979 - 1983 Josai University Faculty of Pharmaceutical Sciences Pharmacy
Professional career (2)：
  • (BLANK)
  • Ph.D.
Work history (13)：
  • 2019/04 - 現在 副学長
  • 2006/04 - 現在 University of Toyama Graduate School of Medicine and Pharmaceutical Sciences Professor
  • 2018/04 - 2019/03 学長補佐
  • 2013/10 - 2018/03 University of Toyama Faculty of Pharmaceutical Sciences Dean
  • 2009/10 - 2013/09 University of Toyama Faculty of Pharmaceutical Sciences Associate Dean
Show all
Committee career (12)：
  • 2008 - 現在 Journal of Pharmaceutical Sciences Editorial Advisory Board
  • 2006 - 現在 日本薬剤学会 評議委員/代議員
  • 2005 - 現在 日本薬物動態学会 評議委員/代議員
  • 2017/04 - 2021/03 日本薬学会 学術誌編集委員長
  • 2010/04 - 2020/03 Frontiers in Drug Metabolism and Transport Review Editor
Show all
Awards (3)：
  • 2021/11 - The Japanese Society for the Study of Xenobiotics JSSX Award
  • 2020/05 - The Academy of Pharmaceutical Science and Technology, Japan The APSTJ Award
  • 2009/11 - American Association of Pharmaceutical Scientists Fellow
Association Membership(s) (5)：
American Association of Pharmaceutical Scientists(AAPS) ,  Association for Research in Vision and Ophthalmology(ARVO) ,  日本薬剤学会 ,  日本薬物動態学会 ,  日本薬学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM