Rchr
J-GLOBAL ID：200901046873639472
Update date: Aug. 27, 2024
Kashiwakura Ikuo
カシワクラ イクオ | Kashiwakura Ikuo
Affiliation and department：
Job title：
Special Assistant to the President
Homepage URL (1)：
http://www.hs.hirosaki-u.ac.jp/~kashiwakura/home.html
Research field (2)：
Radiology
, Cell biology
Research keywords (7)：
サイトカイン
, 造血幹細胞
, 放射線
, Hematopoietic Progenitor Cells
, Cytokine
, Hematopoietic Stem Cell
, Radiation Biology
Research theme for competitive and other funds (29)：
- 2023 - 2027 人工知能を活用した津軽弁から共通語への音声・文字情報変換システムの基盤技術開発
- 2023 - 2026 Elucidating the connection between respiratory diseases among surrounding residents and the characterization of volcanic products from Mt. Etna
- 2021 - 2024 血清アルブミンの放射線による酸化修飾応答と線量・障害予測への応用
- 2018 - 2022 Investigation of dose assessments to the residents at an unique natural radiation area in Sulawesi Island, Indonesia
- 2016 - 2020 Development of the optimal medication for individuals exposed to lethal radiation
- 2016 - 2018 Elucidation of the mechanism of radiation-induced leukemia on human hematopoietic stem cells
- 2015 - 2017 Application of exosomal molecules as exposure dose assessment markers
- 2015 - 2016 母乳育児と母子の尿中に排泄される酸化ストレスマーカーの関連性
- 2013 - 2016 Life-saving effect and mechanism of action of thrombopoietin receptor agonist in radiation-exposed individuals
- 2013 - 2015 Enhancement of radiation therapy for cancer treatment by focusing on pattern recognition receptors
- 2012 - 2015 Relationship between 8-hydroxydeoxyguanosine levels in placental/umbilical cord blood and maternal/neonatal obstetric factors
- 2012 - 2014 Protective effects of a combination of multiple pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation
- 2011 - 2012 Effects of ionizing radiation on the pattern recognition receptors.
- 2010 - 2011 The development of multifunctional drug for magnetic resonance imaging diagnosis that uses metallic complex liquid crystal compound
- 2009 - 2011 The identification of factor (s) which regulate individual radiosensitivity of human hematopoietic stem/progenitor cells and its application
- 2007 - 2008 トリカブトアルカロイド由来新規合成誘導体の放射線増感剤への応用開発研究
- 2006 - 2008 Placental/Umbilical cord blood-derived mesenchymal stem cell-likestroma cells support the hematopoietic recovery of X-irradiated human CD34+ cells
- 2003 - 2005 The study of therapy for radiation-induced thrombocytopenia by using ex vivo expanded-megakaryocyte prepared from auto hematopoietic stem cell.
- 2004 - 2004 新規制癌剤エチニルシチジンによる放射線誘導性血管成長因子の発現抑制と放射線増感
- 2002 - 2004 Experimental study for the recovery from the radiation induced intestinall damage by transplantation of ES cells and stimulation of cytokines in mice.
- 2003 - 2003 NF-κBの関与する放射線抵抗性がんの感受性化機構
- 2003 - 2003 放射線誘発アポトーシスシグナルの低酸素による抑制と低酸素細胞増感剤の影響
- 2000 - 2001 Action of optimum cytokine for the recovery of X-irradiated human hematopoietic stem and progenitor cells
- 1997 - ヒト巨核球・血小板造血の分化増殖に関する研究
- 1997 - ヒト造血前駆細胞の放射線感受性とサイトカインの作用
- 1997 - Proliferation and differentiation of human megakaryopoiesis and thrombopoiesis
- 1997 - Radiosensitivities of human hematopoietic stem and progenitor cells and the function of cytokine
- 造血幹細胞、サイトカイン、放射線、巨核球、再生
- Heamtopoietic stem cells, cytokine, irradiation, megakaryocyte, regeneration
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Papers (174)：
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Yoshiaki Sato, Hironori Yoshino, Junya Ishikawa, Satoru Monzen, Masaru Yamaguchi, Ikuo Kashiwakura. Prediction of hub genes and key pathways associated with the radiation response of human hematopoietic stem/progenitor cells using integrated bioinformatics methods. Scientific reports. 2023. 13. 1. 10762-10762
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Masaru Yamaguchi, Ikuo Kashiwakura. The Acute Radiation Syndrome-Mitigator Romiplostim and Secreted Extracellular Vesicles Improved Survival in Mice Acutely Exposed to Myelosuppressive Doses of Ionizing Radiation. Biomolecules. 2023. 13. 5
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Naoyuki Sano, Hironori Yoshino, Yoshiaki Sato, Hideo Honma, Christopher E J Cordonier, Ikuo Kashiwakura. Cytotoxic activity of unique synthesized five-membered heterocyclic compounds coordinated with tiopronin monovalent. Current pharmaceutical design. 2023. 29. 12. 957-965
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Yoshiaki Sato, Hironori Yoshino, Kota Sato, Ikuo Kashiwakura, Eichi Tsuruga. DAP3-mediated cell cycle regulation and its association with radioresistance in human lung adenocarcinoma cell lines. Journal of radiation research. 2023
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Dwi Ramadhani, Sofiati Purnami, Devita Tetriana, Irawan Sugoro, Viria Agesti Suvifan, Nastiti Rahadjeng, Septelia Inawati Wanandi, Heri Wibowo, Ikuo Kashiwakura, Tomisato Miura, et al. Chromosome aberrations, micronucleus frequency, and catalase concentration in a population chronically exposed to high levels of radon. International journal of radiation biology. 2023. 99. 8. 1188-1203
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MISC (204)：
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Ryohei YAMADA, Osamu OSANAI, Naofumi AKATA, Hirofumi TAZOE, Takakiyo TSUJIGUCHI, Katsuhiro ITO, Hiroyuki HANADA, Shinji TOKONAMI, Ikuo KASHIWAKURA. Efforts to Bioassay for Internal Radiation Dose Assessment at Advanced Radiation Emergency Medical Support Center, Hirosaki University. Japanese Journal of Health Physics. 2023. 58. 1. 27-30
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Mehdi sohrabi, Ikuo Kashiwakura, Shinji Tokonami. NINTH INTERNATIONAL CONFERENCE ON HIGH LEVELS OF ENVIRONMENTAL RADIATION AREAS; FOR UNDERSTANDING CHRONIC LOW-DOSE-RATE RADIATION EXPOSURE HEALTH EFFECTS AND SOCIAL IMPACTS. Radiation Protection Dosimetry (2019). 2019. 184. 3-4. 275-276
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細田正洋, NUGRAHA Eka Djatnika, NUGRAHA Eka Djatnika, SAPUTRA Miki Arian, SAPUTRA Miki Arian, 赤田尚史, 山田涼平, 佐々木道也, 玉熊佑紀, 鈴木崇仁, et al. Influential factors affecting the enhancement of radon in Mamuju, Indonesia. 日本放射線安全管理学会学術大会講演予稿集. 2019. 18th (CD-ROM)
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木立るり子, 工藤幸清, 則包和也, 小山内 暢, 辻口貴清, 小倉巧也, 山田基矢, 清水真由美, 菊池和貴, 床次真司, et al. 放射線について住民と共考するありかたとは?福島県浪江町における支援活動から. 日本看護放射線看護学会第8回学術集会 抄録集. 2019
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松谷 秀哉, 門前 暁, 細田 正洋, 柏倉 幾郎, 加藤 博之. 放射線専攻学生を対象としたEGS5による放射線シミュレーションの教育的評価. 医療情報学連合大会論文集. 2017. 37回. 416-418
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Works (11)：
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都市エリア産学関連事業:「プロテオグリカン応用研究プロジェクト」 (代表・医学科 高垣啓一 教授)
2004 - 2005
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シーズ育成試験研究「自己血清を用いた造血幹・前駆細胞の生体外増幅法の開発」
2005 -
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科学技術振興機構 研究成果活用プラザ宮城 事業化可能性試験「新規ヒト血小板製剤産生システムの開発」
2005 -
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ヒト巨核球・血小板造血を促進する複素環化合物に関する研究
2004 -
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北海道技術士会研究会講師(2000年12月7日) ヒト臍帯血造血幹細胞の生体外増幅-巨核球系造血前駆結胞の特異的増幅をめざし-
2000 -
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Education (2)：
- - 1978 Hokkaido Pharmaceutical University School of Pharmacy Department of Pharmacy
- - 1978 Hokkaido Pharmaceutical University School of Pharmacy Faculty of Pharmaceutical Science
Professional career (1)：
Work history (7)：
- 2014/02 - 2016/01 Hirosaki University
- 2012/02 - 2014/01 弘前大学被ばく医療総合研究所 被ばく医療学部門(兼任)
- 2004 - 2006 弘前大学大学院医学系研究科保健学専攻修士課程 教授
- 2006 - - 弘前大学大学院保健学研究科 教授
- 2002 - 2004 Hirosaki University School of Medicine, School of Health Sciences
- 1978 - 2002 Hokkaido Pharmaceutical University School of Pharmacy
- 1978 - 2002 Hokkaido College of Pharmacy
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Committee career (3)：
- 2009/04 - 2012/03 日本学術振興会学術システム研究センター 専門研究員(医歯薬学班)
- 2004 - 2006 弘前大学大学院医学系研究科保健学専攻 学事委員長
- 2006 - - 弘前大学大学院保健学研究科 学事委員長
Awards (2)：
- 2007 - 日本放射線影響学会第50回大会優秀発表賞
- 1秋山記念生命科学研究助成 2放射線影響協会研究奨励助成 3学術国際振興基金助成
Association Membership(s) (11)：
国際実験血液学会
, 米国血液学会
, 日本医学放射線学会生物部会
, 日本生化学会
, 日本放射線影響学会
, 日本血液学会
, 日本薬学会
, The Japanese Society for Immunology
, The Japan Radiation Research Society
, The Pharmaceutical Society of Japan
, The Japanese Society of Hematology
