2019 - 2024 Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriers
Ayumi Sumino, Takashi Sumikama, Mikihiro Shibata, Katsumasa Irie. Voltage sensors of a Na+ channel dissociate from the pore domain and form inter-channel dimers in the resting state. Nature Communications. 2023
Katsumasa Irie, Yoshinori Oda, Takashi Sumikama, Atsunori Oshima, Yoshinori Fujiyoshi. The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel. Nature Communications. 2023. 14. 1
Ayumi Sumino, Takashi Sumikama, Leonardo Puppulin, Mikihiro Shibata, Katsumasa Irie. Dissociation and inter-channel dimerization of voltage-sensor domains (VSD) of voltage-gated Na+ channel in the resting state. The Journal of Physiological Sciences. 2023. 73. 95
入江克雅. 幅広い単細胞生物のイオンチャネルの構造と機能から根源的な情報伝達手段であるイオン透過の成り立ちに迫る. Institute for Fermentation, Osaka. Research Communications. 2023. 37
入江克雅. Analysis of the divalent cation blocking in ion channels by crystal structure and molecular dynamics simulations. 日本薬学会年会要旨集(Web). 2023. 143rd
入江 克雅. 細胞膜で躍動するタンパク質複合体の意外な素顔 細菌のカルシウムチャネルが示すカルシウム選択的なイオン透過機構(Unexpected operation mechanism of supramolecular machinery working in cell membrane Bacterial calcium channels indicate the universal mechanism of calcium-selective ion permeation). 日本細菌学雑誌. 2022. 77. 1. 37-37
Molecular dynamics simulation and structural analysis of the divalent cation blocking mechanism generated in prokaryotic cation channel
(The 10th Federation of Asian and Oceanian Physiological Societies (FAOPS) Congress 2023)
The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel
(Ion Channel Modulation Symposium - US 2023 in Irvine California 2023)
2022/09 - Biophysical Society of Japan 9th BPPB Editors’ Choice Award The insights into calcium ion selectivity provided by ancestral prokaryotic ion channels
Association Membership(s) (4):
日本薬学会
, 日本細菌学会
, THE PHYSIOLOGICAL SOCIETY OF JAPAN
, THE BIOPHYSICAL SOCIETY OF JAPAN