Yamazaki Kazuhisa

2015 - 2018 Vaccines against periodontitis using DNA ORIGAMI and imidazoquinolines

2015 - 2017 Exploring the alternative pathology of periodontal disease by using ERAI mouse

2013 - 2015 New hypothesis for the pathogenesis of periodontal medicine

2011 - 2014 Analysis of the pathway from periodontal disease to lipid metabolism perturbation

2011 - 2013 Mechanisms Linking Periodontitis to Atherosclerotic Diseases

2011 - 2012 Establishment of the new concept "pathogenic mechanism of periodontal disease by the induction of senescence of the tissues".

2009 - 2011 The effects of regulatory cells on periodontal destruction

2008 - 2010 Biologic pathways for the relationship between periodontitis and cardiovascular disease

2008 - 2009 小胞体ストレスと歯周疾患の関連-病因論の新たなパラダイム構築-

2007 - 2009 Clarification of the pathogenicity of periodontal disease involving exacerbation of metabolic syndrome ; an approach based on immunological characteristics.

2006 - 2008 Mail Medicine using Fingertip Plasma for Screening and Monitoring Periodontitis

2005 - 2007 歯周病原細菌の免疫監視からのエスケープ機構と慢性感染の成立

2004 - 2006 Clarification of the mechanisms for connective tissue destruction and alveolar bone resorption in periodontal disease by comprehensive analysis of infiltrating T cells using immunological and molecular biological techniques

2004 - 2006 The relationship between T-cell and antigen presenting cell associates pathogenesis of periodontitis.

2005 - 2005 歯周病細菌に対する血清抗体価測定法の標準化に関する調査研究

2003 - 2005 Clinical research for relationship between periodontal disease and systemic disease

2002 - 2003 新たな歯周疾患感受性遺伝子の同定

2001 - 2003 Molecular biological and immunological analysis for the relationship between periodontal disease and atherosclerosis

2001 - 2003 Bone homeostasis-related genes associated with susceptibility to periodicities

2001 - 2001 全身疾患と歯周病罹患に関する疫学調査

2000 - 2000 早期発症型歯周炎の病態解析と診断基準確立に向けた共同研究の企画調査

1998 - 2000 Analysis of antigen receptor genes of T cells specific for the periodontal disease

1998 - 2000 Identification of specific genes related to susceptibility to periodontitis

1998 - 2000 Cell adhesion molecules and cytokines in periodontal disease

1998 - 1999 The diversified research on. the genes related periodontal disease

1995 - 1997 Characteristic T cell receptor repertoire and cytokine profile of infiltrating T cells in chronic inflammatory periodontal disease

1993 - 1994 Detection of periodontal disease activity by T cell receptor repertoire and cytokine profile of infiltrating T cells

1991 - 1992 Establishment of Diagnostic Methods of Periodontal Disease Basing on the Alteration of Immunocompetent Cells

1991 - 1992 Expression of collagenase and collagenase inhibitors mRNA in periodontitisaffected human gingival tissue.

1987 - 1988 Relationship between disease activity and the change of lymphocyte subsets in gingival crevicular fluid and gingiva

1985 - 1986 The immune response to periodontopathic bacteria in experimental periodontitis of dogs

歯周炎における自然免疫機構の作用

歯周炎と全身疾患の関連についての研究

歯周炎における機能的T細胞サブセットの検索

歯周炎におけるT細胞レセプターレパートリー検索

Role of innate immune system in periodontal diseases

Studies on the reationship between periodontitis and systemic diseases

Analysis of functional T cell subsets in periodontitis

Analysis of TCR repertoire in periodontitis