Umemoto Eiji

ウメモトエイジ | Umemoto Eiji

Affiliation and department：
Job title： Professor

Research field (1)： Immunology

Research keywords (3)：粘膜免疫 , 白血球動態 , G-protein coupled receptor

Research theme for competitive and other funds (13)：

2022 - 2025 ピルビン酸、乳酸とその受容体GPR31によるパイエル板貪食細胞の抗原捕捉制御
2019 - 2022 Role of the microbial metabolite-macrophage axis in tumor immunity
2016 - 2019 Recognition of bacterial metabolites by GPCR expressed on intestinal phagocytes
2012 - 2017 Characteristics and functions of stromal cells in secondary lymphoid tissues
2012 - 2016 Role of membrane potential in phagocytes

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Papers (63)：

Eri Oguro-Igashira, Mari Murakami, Ryota Mori, Ryuichi Kuwahara, Takako Kihara, Masaharu Kohara, Makoto Fujiwara, Daisuke Motooka, Daisuke Okuzaki, Mitsuru Arase, et al. The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 44. e2318767121
Daichi Kobayashi, Eiji Umemoto, Masayuki Miyasaka. The role of extracellular ATP in homeostatic immune cell migration. Current opinion in pharmacology. 2022. 68. 102331-102331
Qizhi Liu, Eiji Umemoto, Naoki Morita, Hisako Kayama, Yoshihiro Baba, Tomohiro Kurosaki, Ryu Okumura, Kiyoshi Takeda. Pyruvate enhances oral tolerance via GPR31. International Immunology. 2022
Daichi Kobayashi, Yuki Sugiura, Eiji Umemoto, Akira Takeda, Hisashi Ueta, Haruko Hayasaka, Shinsuke Matsuzaki, Tomoya Katakai, Makoto Suematsu, Itaru Hamachi, et al. Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes. Frontiers in Immunology. 2021. 12
Daisuke Takahashi, Naomi Hoshina, Yuma Kabumoto, Yuichi Maeda, Akari Suzuki, Hiyori Tanabe, Junya Isobe, Takahiro Yamada, Kisara Muroi, Yuto Yanagisawa, et al. Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells. EBioMedicine. 2020. 58. 102913-102913

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MISC (14)：

S. Simmons, N. Sasaki, E. Umemoto, N. Yoshizumi, S. Fukuhara, Y. Kitazawa, M. Okudaira, A. Inoue, D. Motooka, S. Nakamura, et al. Implications of Spns2-deficiency on S1P-driven lymphocytes egress, HEV-integrity and immunity. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 267-267
Masayuki Miyasaka, Masayuki Miyasaka, Akira Takeda, Erina Hata, Naoko Sasaki, Eiji Umemoto. S1P and LPA: Regulators of Immune Cell Egress and Ingress in Lymphoid Tissues. Encyclopedia of Immunobiology. 2016. 3. 533-536
ISHIHARA Sayaka, NISHIKIMI Akihiko, UMEMOTO Eiji, MASAYUKI Miyasaka, KATAGIRI Koko. Regulation of adhesion cascades of naieve and offector T cells by Rap1 is critical for mucosal homeostasis. 日本免疫学会総会・学術集会記録. 2016. 45. Proceedings
Pia Rantakari, Kaisa Auvinen, Norma Jappinen, Maria Kapraali, Joona Valtonen, Marika Karikoski, Heidi Gerke, Imtiaz Iftakhar-E-Khuda, Johannes Keuschnigg, Eiji Umemoto, et al. The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes (vol 16, pg 386, 2015). NATURE IMMUNOLOGY. 2015. 16. 5. 544-544
Generation of colonic IgA-secreting cells in the caecal patch. 2014. 251. 1. 29-34

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Books (2)：

Education (3)：

Professional career (2)：

Work history (5)：

2020/04 - 現在 Shizuoka University Laboratory of Microbiology and Immunology, School of Pharmaceutical Sciences Professor
2012/04 - 2020/03 Osaka University Graduate School of Medicine Associate professor
2012/04 - 2020/03 Osaka University WPI Immunology Frontier Research Center
2007/12 - 2012/03 Osaka University Graduate School of Medicine
2005/04 - 2007/11 Osaka University Graduate School of Medicine

Association Membership(s) (3)：

日本薬学会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 日本免疫学会

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