Kobayashi Tadaharu

Affiliation and department：
Job title： Professor

Research field (1)： Surgical dentistry

Research keywords (1)： oral and maxillofacial surgery

Research theme for competitive and other funds (24)：

2023 - 2026 がん薬物療法を受ける患者の口腔環境,口腔細菌叢とQOLの関連性の解明
2021 - 2024 低酸素微小環境を標的としたコルジセピン誘導体による口腔がん治療の検討
2021 - 2024 外科的矯正治療の適応判断に有用な顎顔面形態指標を組み入れた日本版IOFTNの策定
2020 - 2023 The construction of a simulation model to explain the nasopharyngeal airway morphologies in patients with jaw deformity
2019 - 2023 Construction of new occlusal evaluation system using 3D images in cleft palate patients

2019 - 2023 Subjective and objective evaluation of community development that facilitates citizens participation

2018 - 2021 Effect of deteriorated bone quality associated with vitamin C deficiency on the development of progressive condylar resorption and development of preventive methods

2016 - 2019 Rebuilding Identity in Patients with Oral Cancer; Changes in quality of life and clarification of associated factors

2015 - 2018 Analysis of the effect on nasal cavity morphology and nasal air resistance by maxillo-mandibular orthognathic surgery

2014 - 2017 Histological examination of bone regeneration and cell kinetics induced by mesenchymal stem cells: comparison of bone marrow cells with adipose tissue cells

2013 - 2016 Clarification of risk factors for progressive condylar resorption and development of prevention method with intermittent PTH(1-34) treatment

2010 - 2012 Clarification of pathogenic mechanism of PCR and development of the prevention method -a study with rat mandibular distraction model-

2009 - 2012 Establishment of application criteria of maxillomandibular advancement surgery in Japanese patients with sleep apnea syndrome

2008 - 2010 The investigation of skeletal risk factor for Japanese patients with Obstructive Sleep Apnea Syndrome (OSAS)

2007 - 2009 Therapeutic new trial to OSAS : Effectiveness of EMS

2006 - 2008 Acceleration of bone formation on mandibular distraction osteogenesis

2005 - 2007 Investigation of safety standards in orthognathic surgery-effects of mandibular setback surgery on oropharyngeal airway and respiratory function during sleep-

2001 - 2004 Accelerates bone maturation with the synthetic 3-benzothiepin derivative in distraction osteogenesis in rats.

2001 - 2003 The establishment of functional-morphological and respiration-physiologic diagnosis of the upper respiratory tract failure in the postoperative

2001 - 2002 The effect of materials and shapes to the biomechanics in transmandibular implants

2000 - 2000 国際規格による唇顎口蓋裂患者顎顔面発育の多施設比較研究のための企画調査

1996 - 1998 睡眠時無呼吸症候群の歯科における集学的治療法の確立

1993 - 1994 Study for the etiological diagnosis of obstructive sleep apnea and survey in oral and maxillofacial diseases.

1991 - 1993 Masticatory function in patients with jaw deformity before and after orthognathic surgery

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Papers (331)：

Zhuoyang Zheng, Daichi Hasebe, Daisuke Suda, Naoaki Saito, Daisuke Saito, Jun Nihara, Kaname Nohno, Isao Saito, Tadaharu Kobayashi. Investigation of orthognathic surgery indicators-combination with index of orthognathic functional treatment needs (IOFTN) and maxillofacial morphometric analysis. Oral and maxillofacial surgery. 2024
Mai Nozawa-Kobayashi, Hidenobu Sakuma, Hiroko Kanemaru, Akira Kurokawa, Marie Soga, Moe Yamashita, Kanae Niimi, Tadaharu Kobayashi. Survey of the association between tooth extraction and development of medication-related osteonecrosis of the jaw in patients undergoing cancer treatment with bone-modifying agents. Oral and maxillofacial surgery. 2024
寺田愛希, 市川佳弥, 丹原惇, 児玉泰光, 小林正治, 齋藤功. 新潟大学医歯学総合病院においてPNAM治療を行った片側性口唇口蓋裂児における外鼻形態変化の長期的評価と治療効果に影響を与える因子. 新潟歯学会雑誌. 2024. 53. 2. 91-92
山田貴大, 丹原惇, 西山秀昌, 小林正治, 齋藤功. 下顎偏位を伴う骨格性下顎前突症の顎矯正手術後における顎関節形態と顔面形態との関連. 新潟歯学会雑誌. 2024. 53. 2. 100-101
橋爪孝介, 片桐渉, 竹内涼子, 須田大亮, 小林正治. 骨髄由来間葉系幹細胞培養上清に含まれるMCP-1はマクロファージ極性転換により骨形成を促進する. 新潟歯学会雑誌. 2024. 53. 2. 90-91

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MISC (374)：

羽賀健太, 船山昭典, 長谷部大地, 佐久間英伸, 齋藤大輔, 新美奏恵, 曽束洋平, 山崎学, 田沼順一, 林孝文, et al. Extensive ameloblastic fibroma of the mandible in a middle-aged female. 日本口腔腫瘍学会総会・学術大会プログラム・抄録集. 2023. 41st
笠原公輝, 長谷部大地, 原太一, 須田大亮, 佐久間英伸, 齋藤直朗, 齋藤大輔, 齋藤功, 小林正治. 多分割Le Fort I型骨切り術の術後安定性の検討. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
大湊麗, 大湊麗, 大湊麗, 小野和宏, 小野和宏, 児玉泰光, 結城龍太郎, 永井孝宏, 小林亮太, 市川佳弥, et al. The relationship between preoperative posterior cleft width and postoperative primary occlusion. 日本口蓋裂学会雑誌. 2023. 48. 2
船山昭典, 三上俊彦, 三上俊彦, 新美奏恵, 新美奏恵, 芳澤享子, 羽賀健太, 齋藤大輔, 長谷部大地, 佐久間英伸, et al. Trends and pathogenesis of patients diagnosed with malignant tumors in the oral and maxillofacial region in our department during the past 20 years. 新潟歯学会雑誌. 2023. 53. 1
齋藤大輔, 原太一, 須田大亮, 齋藤直朗, 佐久間英伸, 長谷部大地, 片桐渉, 小林正治. 顎矯正手術における3DシミュレーションとCAD/CAMサージカルガイドプレートならびに超音波切削機器の応用. 日本顎変形症学会雑誌. 2022. 32. 2. 158-158

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Books (5)：

Swiching between M1 and M2 macrophage phenotypes by the conditioned media of bone marrow derived mesenchymal stem cells promotes bone regeneration.
2019
口腔の病気と全身の健康
福岡歯科大学 2011
口腔解剖学
医歯薬出版 2009
切開と縫合の基本と臨床
ヒョーロン・パブリッシャーズ 2003
口と歯の病気マップ
医歯薬出版 2003

Lectures and oral presentations (11)：

22-7-O44-31 歯科領域における周術期患者の抗菌薬使用実態調査 : 経口スイッチ療法の評価(感染制御,口頭発表,一般演題,医療薬学の進歩と未来-次の四半世紀に向けて-)
(日本医療薬学会年会講演要旨集 2015)
4 頭頸部腺様嚢胞癌の転移様相(I.一般演題,第66回新潟癌治療研究会)
(新潟医学会雑誌 2008)
4 外科療法を行った舌扁平上皮がんの治療成績(一般演題,第63回新潟癌治療研究会)
(新潟医学会雑誌 2003)
<学会記事>2 口腔扁平上皮癌における両側頚部郭清術施行例の臨床的検討(I. 一般演題)(第 61 回新潟癌治療研究会)
(新潟医学会雑誌 2002)
顎裂骨移植部における永久歯咬合再建に関する臨床的検討
(日本口蓋裂学会雑誌 2001)

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Work history (6)：

2013/04/01 - 現在 Niigata University Faculty of Dentistry School of Dentistry Professor
2013/04 - 現在 Niigata University Graduate School of Medical and Dental Sciences Division of Reconstructive Surgery for Oral and Maxillofacial Region Professor
2003/10 - 2013/03 Niigata University University Medical and Dental Hospital Oral Surgery,Radiology and Anesthesia Oral Reconstructive Surgery Lecturer
2003/01 - 2003/09 Niigata University University Dental Hospital Lecturer
2001/04 - 2002/12 新潟大学大学院医歯学総合研究科組織再建口腔外科学分野助手

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