Iwata Makoto

イワタマコト | Iwata Makoto

Affiliation and department：
Homepage URL (1)： https://eito.w.waseda.jp/main-en/member-en.html

Research field (6)： Hygiene and public health (non-laboratory) , Hygiene and public health (laboratory) , Healthcare management, medical sociology , Immunology , Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (16)： retinoic acid , 樹状細胞 , レチノイド , ホルモン , ステロイド , ビタミン , 細胞分化 , ホーミング , 免疫 , retinoid , hormone , steroid , vitamin , cell differentiation , homing , Immunity

Research theme for competitive and other funds (21)：

2019 - 2022 濾胞性ヘルパーT細胞の分化における生理的低酸素の役割
2014 - 2017 IL-13を高生産する新規炎症性ヘルパーT細胞のアレルギー炎症性疾患における役割
2013 - 2015 免疫空間における腸型樹状細胞の誘導とその攪乱
2011 - 2014 樹状細胞の分化系列とレチノイン酸産生能のエピジェネティック制御の関係解明
2013 - 2014 レチノイン酸による炎症性疾患の制御

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Papers (72)：

Makoto Iwata, Ayumi Takada, Rei Sakamoto, Si-Young Song, Etsuro Ito. The active form of vitamin D (calcitriol) promotes CXCR5 expression during follicular helper T cell differentiation. International Immunology. 2024
Rei Sakamoto, Ayumi Takada, Shinnosuke Yamakado, Haruki Tsuge, Etsuro Ito, Makoto Iwata. Release from persistent T cell receptor engagement and blockade of aryl hydrocarbon receptor activity enhance IL-6-dependent mouse follicular helper T-like cell differentiation in vitro. PLoS ONE. 2023. 18. 6. e0287746
Aya Yokota-Nakatsuma, Yoshiharu Ohoka, Hajime Takeuchi, Si-Young Song, Makoto Iwata. Beta1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. SCIENTIFIC REPORTS. 2016. 6
Isao Okayasu, Kiyomi Hana, Noriko Nemoto, Tsutomu Yoshida, Makoto Saegusa, Aya Yokota-Nakatsuma, Si-Young Song, Makoto Iwata. Vitamin A Inhibits Development of Dextran Sulfate Sodium-Induced Colitis and Colon Cancer in a Mouse Model. BIOMED RESEARCH INTERNATIONAL. 2016. 2016
A Yokota-Nakatsuma, H Takeuchi, Y Ohoka, C Kato, S-Y Song, T Hoshino, H Yagita, T Ohteki, M Iwata. Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells. Mucosal Immunol. 2014. 7. 4. 786-801

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MISC (33)：

J. Rodrigo Mora, Makoto Iwata. Retinoids and the Immune System. The Retinoids: Biology, Biochemistry, and Disease. 2015. 465-483
佐藤貴之, 北脇年雄, 藤田晴之, 岩田誠, 伊豫田智典, 稲葉カヨ, 樗木俊聡, 坂井義治, 高折晃史, 門脇則光. ビタミンD刺激によってレチノイン酸を高産生するヒト樹状細胞の同定. 日本がん免疫学会総会プログラム・抄録集. 2013. 17回. 144-144
Factors responsible for retinoic acid-producing ability in intestinal dendritic cells. Clinical immunology & allergology. 2010. 54. 4. 492-498
Makoto Iwata. Retinoic acid production by intestinal dendritic cells and its role in T-cell trafficking. SEMINARS IN IMMUNOLOGY. 2009. 21. 1. 8-13
Makoto Iwata. The roles of retinoic acid in lymphocyte differentiation. SEMINARS IN IMMUNOLOGY. 2009. 21. 1. 1-1

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Patents (4)：

T細胞の腸組織へのホーミング誘導剤
新規蛋白質およびこれをコードするDNA
新規DNAおよびその利用
新規タンパク質およびこれをコードする遺伝子

Books (16)：

Retinoids and the immune system
Wiley-Blackwell 2015 ISBN:9781118627983
機能性食品の作用と安全性百科
丸善出版 2012
食品免疫・アレルギーの事典
朝倉書店 2011
Retinoic acid production by intestinal dendritic cells
Elsevier 2011
臨床粘膜免疫学
シナジー 2010

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Lectures and oral presentations (57)：

腸管免疫系の発達と機能制御 - その鍵を握るレチノイン酸
(早稲田大学先端生命医科学センター(TWIns)セミナー 2018)
Regulation of immunity and allergy by retinoic acid
(Frontier of Genomic Medicine“Retinoid (Am80, Tamibarotene) as therapeutics for intractable diseases” 2018)
リンパ球の動態と分化について
(日本歯科大学第27回発生・再生医科学セミナー 2017)
ステロイドとレチノイン酸による免疫機能の制御
(徳島大学大学院医科学教育部・栄養生命科学教育部・口腔科学教育部、大学院特別講義&クラスターコアセミナー(感染・免疫) 2016)
腸管免疫系の発達と機能制御 -その鍵を握るレチノイン酸-
(第52回日本小児アレルギー学会・教育講演 2015)

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Education (4)：

- 1980 The University of Tokyo
- 1980 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
- 1975 The University of Tokyo Faculty of Science Department of Chemistry
- 1975 The University of Tokyo Faculty of Science Department of Chemistry

Professional career (1)：

Ph.D. (The University of Tokyo)

Committee career (4)：

2008/10 - 2020/09 The Japanese Society for Immunology Councilor
2008/10 - 2020/09 日本免疫学会評議員
2013/02 - 2018/01 Pharmaceutical Society of Japan Representative
2013/02 - 2018/01 日本薬学会代議員

Awards (8)：

2013/10 - Japanese Association for Food Immunology Award
2013 - The Uehara Memorial Foundation Research Grant
2010 - ダノン学術研究助成金
2010 - The Danone Institute of Japan Foundation Research Grant
2008 - 上原記念生命科学財団研究助成金

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Association Membership(s) (5)：

American Association of Immunologists , Japanese Association for Food Immunology , 日本レチノイド研究会 , 日本薬学会 , 日本免疫学会

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